StarFunc result for job id Q9H3H5

User Input

>input (408 residues)
MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGV
ISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL
RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFC
TNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLY
HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP
RHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNN
MTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:P42867	0.988	0.983	3.880E-58	410	0.941	0.937	P42867.pdb.gz	GPT_MOUSE UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Mus musculus OX=10090 GN=Dpagt1 PE=1 SV=2
2	PDB:5o5eA	0.923	0.988	6.275E-51	381	0.929	0.995	5o5eA.pdb.gz	Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
3	PDB:6bw5D	0.878	0.989	1.651E-45	362	0.877	0.989	6bw5D.pdb.gz	GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation.
4	AFDB:P42881	0.929	0.852	5.770E-33	446	0.436	0.399	P42881.pdb.gz	GPT_SCHPO UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gpt2 PE=3 SV=1
5	AFDB:P07286	0.923	0.843	6.074E-32	448	0.419	0.382	P07286.pdb.gz	GPT_YEAST UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=ALG7 PE=3 SV=1
6	AFDB:Q9M2M5	0.795	0.762	2.828E-27	426	0.417	0.399	Q9M2M5.pdb.gz	Q9M2M5_ARATH UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Arabidopsis thaliana OX=3702 GN=F28O9.70 PE=1 SV=1
7	AFDB:Q383N4	0.809	0.840	2.182E-26	393	0.360	0.374	Q383N4.pdb.gz	Q383N4_TRYB2 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.01.2220 PE=3 SV=1
8	AFDB:O34753	0.624	0.705	1.004E-10	358	0.172	0.196	O34753.pdb.gz	TAGO_BACSU Probable undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase OS=Bacillus subtilis (strain 168) OX=224308 GN=tagO PE=1 SV=1
9	AFDB:G3XD50	0.543	0.641	7.743E-10	339	0.167	0.201	G3XD50.pdb.gz	G3XD50_PSEAE Glycosyltransferase WbpL OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=wbpL PE=4 SV=1
10	AFDB:P9WMW5	0.621	0.627	8.846E-10	404	0.181	0.183	P9WMW5.pdb.gz	WECA_MYCTU Decaprenyl-phosphate N-acetylglucosaminephosphotransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=wecA PE=1 SV=1
11	PDB:6oyhD	0.627	0.748	9.550E-10	337	0.157	0.190	6oyhD.pdb.gz	Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
12	AFDB:O66465	0.570	0.640	5.973E-9	359	0.174	0.198	O66465.pdb.gz	MRAY_AQUAE Phospho-N-acetylmuramoyl-pentapeptide-transferase OS=Aquifex aeolicus (strain VF5) OX=224324 GN=mraY PE=1 SV=1
13	AFDB:P0A6W3	0.618	0.693	1.389E-8	360	0.152	0.172	P0A6W3.pdb.gz	MRAY_ECOLI Phospho-N-acetylmuramoyl-pentapeptide-transferase OS=Escherichia coli (strain K12) OX=83333 GN=mraY PE=1 SV=1
14	PDB:6oz6D	0.541	0.745	2.371E-6	288	0.142	0.201	6oz6D.pdb.gz	Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
15	PDB:7wnxA	0.108	0.072	1.646E-1	734	0.125	0.069	7wnxA.pdb.gz	Cryo-EM structure of Mycobacterium smegmatis MmpL3 complexed with ST004 in lipid nanodiscs
16	PDB:3nogA	0.141	0.069	4.002E-1	1012	0.074	0.030	3nogA.pdb.gz
17	PDB:7yziA	0.145	0.152	4.780E-1	378	0.100	0.108	7yziA.pdb.gz	Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases.
18	PDB:8b8mB	0.140	0.101	5.461E-1	682	0.140	0.084	8b8mB.pdb.gz	Structural basis for the activation of the lipid scramblase TMEM16F.
19	PDB:2b6pA	0.155	0.212	7.453E-1	261	0.105	0.165	2b6pA.pdb.gz
20	PDB:4gbyA	0.162	0.144	7.453E-1	475	0.076	0.065	4gbyA.pdb.gz	Crystal structure of a bacterial homologue of glucose transporters GLUT1-4.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	A0A8I6GKZ9	0.0	581	385	0.723	0.766	A0A8I6GKZ9_RAT UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Rattus norvegicus OX=10116 GN=Dpagt1 PE=1 SV=1
2	F7EMK2	0.0	709	397	0.870	0.894	F7EMK2_RAT UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Rattus norvegicus OX=10116 GN=Dpagt1 PE=1 SV=1
3	P24140	0.0	753	408	0.939	0.939	GPT_CRIGR UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Cricetulus griseus OX=10029 GN=DPAGT1 PE=1 SV=1
4	P42867	0.0	743	410	0.939	0.934	GPT_MOUSE UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Mus musculus OX=10090 GN=Dpagt1 PE=1 SV=2
5	Q6P4Z8	0.0	741	410	0.934	0.929	Q6P4Z8_RAT UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Rattus norvegicus OX=10116 GN=Dpagt1 PE=2 SV=1
6	Q9H3H5	0.0	825	408	1.000	1.000	GPT_HUMAN UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Homo sapiens OX=9606 GN=DPAGT1 PE=1 SV=2
7	P42881	6.42e-100	306	446	0.446	0.408	GPT_SCHPO UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=gpt2 PE=3 SV=1
8	P07286	2.21e-98	302	448	0.414	0.377	GPT_YEAST UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=ALG7 PE=3 SV=1
9	Q9M2M5	1.38e-95	294	426	0.431	0.413	Q9M2M5_ARATH UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Arabidopsis thaliana OX=3702 GN=F28O9.70 PE=1 SV=1
10	Q383N4	7.45e-76	243	393	0.360	0.374	Q383N4_TRYB2 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.01.2220 PE=3 SV=1
11	O34753	2.53e-09	60.8	358	0.125	0.142	TAGO_BACSU Probable undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase OS=Bacillus subtilis (strain 168) OX=224308 GN=tagO PE=1 SV=1
12	O66465	2.58e-04	45.1	359	0.108	0.123	MRAY_AQUAE Phospho-N-acetylmuramoyl-pentapeptide-transferase OS=Aquifex aeolicus (strain VF5) OX=224324 GN=mraY PE=1 SV=1
13	P9WMW5	0.005	41.2	404	0.066	0.067	WECA_MYCTU Decaprenyl-phosphate N-acetylglucosaminephosphotransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=wecA PE=1 SV=1
14	P0A6W3	0.088	37.4	360	0.105	0.119	MRAY_ECOLI Phospho-N-acetylmuramoyl-pentapeptide-transferase OS=Escherichia coli (strain K12) OX=83333 GN=mraY PE=1 SV=1
15	G3XD50	0.12	36.6	339	0.157	0.189	G3XD50_PSEAE Glycosyltransferase WbpL OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=wbpL PE=4 SV=1
16	Q7B798	0.12	36.6	339	0.157	0.189	Q7B798_PSEAI Glycosyl transferase OS=Pseudomonas aeruginosa OX=287 GN=GUL26_04445 PE=4 SV=1
17	Q9R273	0.64	34.3	248	0.066	0.109	Q9R273_RAT Ryanodine receptor type 3 (Fragment) OS=Rattus norvegicus OX=10116 GN=Ryr3 PE=2 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00953 Glycos_transf_4	6e-35	132.1	Glycosyl transferase family 4

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000386597

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000378260	0.999	Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13
2	9606.ENSP00000359224	0.996	UDP-N-acetylglucosamine transferase subunit ALG14 homolog
3	9606.ENSP00000360644	0.987	Dolichol-phosphate mannosyltransferase subunit 1
4	9606.ENSP00000239891	0.983	ALG5, dolichyl-phosphate beta-glucosyltransferase
5	9606.ENSP00000361667	0.976	Dolichol kinase
6	9606.ENSP00000361625	0.969	Dolichyldiphosphatase 1
7	9606.ENSP00000357384	0.953	Dolichol-phosphate mannosyltransferase subunit 3
8	9606.ENSP00000322181	0.949	Dolichol phosphate-mannose biosynthesis regulatory protein
9	9606.ENSP00000430236	0.872	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
10	9606.ENSP00000360149	0.853	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
11	9606.ENSP00000299626	0.848	Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
12	9606.ENSP00000262374	0.842	Chitobiosyldiphosphodolichol beta-mannosyltransferase
13	9606.ENSP00000268261	0.819	Phosphomannomutase 2
14	9606.ENSP00000333813	0.814	Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase
15	9606.ENSP00000417764	0.808	Alpha-1,3/1,6-mannosyltransferase ALG2
16	9606.ENSP00000250498	0.783	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
17	9606.ENSP00000349860	0.766	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
18	9606.ENSP00000309092	0.755	Mannose-1-phosphate guanyltransferase beta
19	9606.ENSP00000353104	0.751	Dehydrodolichyl diphosphate synthase complex subunit DHDDS
20	9606.ENSP00000376472	0.743	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0003975	1.000	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
GO:0005515	0.981	protein binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0071704	0.997	organic substance metabolic process
GO:0044237	0.997	cellular metabolic process
GO:0044238	0.995	primary metabolic process
GO:0006807	0.994	nitrogen compound metabolic process
GO:0044249	0.990	cellular biosynthetic process
GO:0044255	0.987	cellular lipid metabolic process
GO:0009059	0.985	macromolecule biosynthetic process
GO:1901564	0.979	organonitrogen compound metabolic process
GO:0006486	0.965	protein glycosylation
GO:0044281	0.962	small molecule metabolic process
GO:0006487	0.954	protein N-linked glycosylation
GO:0006490	0.941	oligosaccharide-lipid intermediate biosynthetic process
GO:0006720	0.817	isoprenoid metabolic process
GO:1901615	0.360	organic hydroxy compound metabolic process
GO:0006488	0.333	dolichol-linked oligosaccharide biosynthetic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005737	1.000	cytoplasm
GO:0043231	1.000	intracellular membrane-bounded organelle
GO:0012505	0.999	endomembrane system
GO:0031090	0.995	organelle membrane
GO:0005789	0.987	endoplasmic reticulum membrane

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name
RHEA:13289	1.000	a dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-diphosphodolichol + UMP
EC:2.7.8.15	1.000	N-acetylglucosaminephosphotransferase.

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