StarFunc result for job id Q9UGU0

User Input

>input (1960 residues)
MQSFREQSSYHGNQQSYPQEVHGSSRLEEFSPRQAQMFQNFGGTGGSSGSSGSGSGGGRR
GAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSGPVQSYGP
PQGSSFGNQYGSEGHVGQFQAQHSGLGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQV
QQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQLRVGQFGQHYQSSAS
SSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNF
EQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQF
HQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSP
TPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALT
PQKKTSKRPSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQ
STSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVN
EKTVGVIVSREAMTGRVEKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPGG
GGSKGNKNGDNNSNHNGEGNGQSGHSAAGPGFTSRTEPSKSPGSLRYSYKDSFGSAVPRN
VSGFPQYPTGQEKGDFTGHGERKGRNEKFPSLLQEVLQGYHHHPDRRYSRSTQEHQGMAG
SLEGTTRPNVLVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLTDYP
IPRKFEIEPQSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMSADTRIGRNDRL
NPTLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNNKKSGDHCHPPSIKHES
YRGNASPGAATHDSLSDYGPQDSRPTPMRRVPGRVGGREGMRGRSPSQYHDFAEKLKMSP
GRSRGPGGDPHHMNPHMTFSERANRSSLHTPFSPNSETLASAYHANTRAHAYGDPNAGLN
SQLHYKRQMYQQQPEEYKDWSSGSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDK
DGMMYGPPVGTYHDPSAQEAGRCLMSSDGLPNKGMELKHGSQKLQESCWDLSRQTSPAKS
SGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLPGQEDHSSQNPLIMRRRVRSF
ISPIPSKRQSQDVKNSSTEDKGRLLHSSKEGADKAFNSYAHLSHSQDIKSIPKRDSSKDL
PSPDSRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASSNSAEAGGDTV
TLDDILSLKSGPPEGGSVAVQDADIEKRKGEVASDLVSPANQELHVEKPLPRSSEEWRGS
VDDKVKTETHAETVTAGKEPPGAMTSTTSQKPGSNQGRPDGSLGGTAPLIFPDSKNVPPV
GILAPEANPKAEEKENDTVTISPKQEGFPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPP
PQPPQIPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQP
LDKTDAKNKSFYPYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESK
ALPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPK
RATEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCGGGPR
SLSRGLPCKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCIL
WANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLL
HEENFSVRCPKHKPPLPCPLPPLQNKTAKGSLSTEQSERG

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q9EPQ8	0.200	0.199	0.000	1987	0.926	0.913	Q9EPQ8.pdb.gz	TCF20_MOUSE Transcription factor 20 OS=Mus musculus OX=10090 GN=Tcf20 PE=1 SV=3
2	AFDB:Q9UGU0	1.000	1.000	0.000	1960	1.000	1.000	Q9UGU0.pdb.gz	TCF20_HUMAN Transcription factor 20 OS=Homo sapiens OX=9606 GN=TCF20 PE=1 SV=3
3	AFDB:Q61818	0.093	0.095	4.764E-39	1889	0.239	0.248	Q61818.pdb.gz	RAI1_MOUSE Retinoic acid-induced protein 1 OS=Mus musculus OX=10090 GN=Rai1 PE=1 SV=3
4	AFDB:Q7Z5J4	0.076	0.077	1.328E-38	1906	0.236	0.243	Q7Z5J4.pdb.gz	RAI1_HUMAN Retinoic acid-induced protein 1 OS=Homo sapiens OX=9606 GN=RAI1 PE=1 SV=2
5	AFDB:Q8IRW8	0.054	0.045	5.081E-11	2431	0.164	0.132	Q8IRW8.pdb.gz	TRR_DROME Histone-lysine N-methyltransferase trr OS=Drosophila melanogaster OX=7227 GN=trr PE=1 SV=2
6	AFDB:Q12888	0.031	0.031	3.351E-4	1972	0.140	0.139	Q12888.pdb.gz	TP53B_HUMAN TP53-binding protein 1 OS=Homo sapiens OX=9606 GN=TP53BP1 PE=1 SV=2
7	AFDB:F1M842	0.028	0.028	1.001E-2	1972	0.146	0.145	F1M842.pdb.gz	F1M842_RAT Tumor protein p53 binding protein 1 OS=Rattus norvegicus OX=10116 GN=Tp53bp1 PE=1 SV=3
8	AFDB:Q9UPS6	0.030	0.030	2.617E-2	1966	0.122	0.122	Q9UPS6.pdb.gz	SET1B_HUMAN Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens OX=9606 GN=SETD1B PE=1 SV=3
9	AFDB:Q9VQI9	0.029	0.033	3.605E-2	1673	0.112	0.131	Q9VQI9.pdb.gz	AFFL_DROME AF4/FMR2 family member lilli OS=Drosophila melanogaster OX=7227 GN=lilli PE=1 SV=2
10	AFDB:C4XZ24	0.036	0.034	6.020E-2	2164	0.125	0.113	C4XZ24.pdb.gz	FLO11_CLAL4 Flocculation protein FLO11 OS=Clavispora lusitaniae (strain ATCC 42720) OX=306902 GN=FLO11 PE=3 SV=1
11	PDB:3k1lA	0.018	0.077	1.883	376	0.006	0.032	3k1lA.pdb.gz	The structure of the catalytic subunit FANCL of the Fanconi anemia core complex
12	PDB:7qsoC	0.015	0.074	2.433	210	0.003	0.029	7qsoC.pdb.gz	Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
13	PDB:1dw9A	0.011	0.118	4.332	156	0.003	0.032	1dw9A.pdb.gz
14	PDB:7dvqC	0.014	0.024	4.618	902	0.006	0.013	7dvqC.pdb.gz	Structure of the activated human minor spliceosome.
15	PDB:4mqwB	0.016	0.136	5.597	109	0.006	0.110	4mqwB.pdb.gz
16	PDB:4v6iBl	0.012	0.155	6.363	88	0.004	0.091	4v6iBl.pdb.gz	Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
17	PDB:7peqAJ	0.011	0.020	6.363	996	0.005	0.009	7peqAJ.pdb.gz
18	PDB:2af6G	0.009	0.066	6.784	246	0.002	0.016	2af6G.pdb.gz	Structure of the Mycobacterium tuberculosis Flavin Dependent Thymidylate Synthase (MtbThyX) at 2.0A Resolution.
19	PDB:7oyaE1	0.018	0.104	6.784	206	0.003	0.024	7oyaE1.pdb.gz	A molecular network of conserved factors keeps ribosomes dormant in the egg.
20	PDB:1hcnB	0.016	0.127	7.233	110	0.006	0.109	1hcnB.pdb.gz

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q66JM6	0.0	1938	1068	0.504	0.924	Q66JM6_MOUSE Tcf20 protein (Fragment) OS=Mus musculus OX=10090 GN=Tcf20 PE=2 SV=1
2	Q9EPQ8	0.0	3299	1987	0.915	0.902	TCF20_MOUSE Transcription factor 20 OS=Mus musculus OX=10090 GN=Tcf20 PE=1 SV=3
3	Q9UGU0	0.0	4006	1960	1.000	1.000	TCF20_HUMAN Transcription factor 20 OS=Homo sapiens OX=9606 GN=TCF20 PE=1 SV=3
4	W5ZR30	0.0	4006	1960	1.000	1.000	W5ZR30_HUMAN Transcription factor 20 OS=Homo sapiens OX=9606 GN=TCF20 PE=2 SV=1
5	Q61818	5.11e-29	130	1889	0.024	0.025	RAI1_MOUSE Retinoic acid-induced protein 1 OS=Mus musculus OX=10090 GN=Rai1 PE=1 SV=3
6	Q8IRW8	4.07e-15	84.3	2431	0.018	0.014	TRR_DROME Histone-lysine N-methyltransferase trr OS=Drosophila melanogaster OX=7227 GN=trr PE=1 SV=2
7	A8MXE8	1.04e-14	82.8	942	0.044	0.091	A8MXE8_HUMAN Retinoic acid induced 1 (Fragment) OS=Homo sapiens OX=9606 GN=RAI1 PE=1 SV=1
8	Q7Z5J4	2.89e-14	81.6	1906	0.044	0.045	RAI1_HUMAN Retinoic acid-induced protein 1 OS=Homo sapiens OX=9606 GN=RAI1 PE=1 SV=2
9	Q8NEZ4	3.70e-14	81.3	4911	0.017	0.007	KMT2C_HUMAN Histone-lysine N-methyltransferase 2C OS=Homo sapiens OX=9606 GN=KMT2C PE=1 SV=3
10	A0A8I6A4Z1	2.14e-13	79.0	5003	0.016	0.006	A0A8I6A4Z1_RAT [histone H3]-lysine(4) N-methyltransferase OS=Rattus norvegicus OX=10116 GN=Kmt2c PE=1 SV=1
11	A0A8I6A900	2.18e-13	79.0	4946	0.016	0.006	A0A8I6A900_RAT [histone H3]-lysine(4) N-methyltransferase OS=Rattus norvegicus OX=10116 GN=Kmt2c PE=1 SV=1
12	A0A8I6A825	2.21e-13	79.0	4952	0.016	0.006	A0A8I6A825_RAT [histone H3]-lysine(4) N-methyltransferase OS=Rattus norvegicus OX=10116 GN=Kmt2c PE=1 SV=1
13	A0A8I6G4C0	2.21e-13	79.0	4986	0.016	0.006	A0A8I6G4C0_RAT [histone H3]-lysine(4) N-methyltransferase OS=Rattus norvegicus OX=10116 GN=Kmt2c PE=1 SV=1
14	Q8BRH4	2.31e-13	79.0	4903	0.016	0.007	KMT2C_MOUSE Histone-lysine N-methyltransferase 2C OS=Mus musculus OX=10090 GN=Kmt2c PE=1 SV=2
15	O14686	8.65e-12	73.6	5537	0.017	0.006	KMT2D_HUMAN Histone-lysine N-methyltransferase 2D OS=Homo sapiens OX=9606 GN=KMT2D PE=1 SV=2
16	Q6PDK2	9.03e-12	73.6	5588	0.017	0.006	KMT2D_MOUSE Histone-lysine N-methyltransferase 2D OS=Mus musculus OX=10090 GN=Kmt2d PE=1 SV=2
17	P20659	3.72e-11	71.6	3726	0.015	0.008	TRX_DROME Histone-lysine N-methyltransferase trithorax OS=Drosophila melanogaster OX=7227 GN=trx PE=1 SV=4
18	F4I443	1.38e-09	65.9	714	0.016	0.045	BARD1_ARATH BRCA1-associated RING domain protein 1 OS=Arabidopsis thaliana OX=3702 GN=BARD1 PE=1 SV=1
19	A8VKP8	8.64e-09	63.5	4218	0.015	0.007	A8VKP8_DANRE Histone-lysine N-methyltransferase OS=Danio rerio OX=7955 GN=im:7148357 PE=1 SV=1
20	F1QL52	9.97e-09	63.5	4219	0.015	0.007	F1QL52_DANRE Histone-lysine N-methyltransferase OS=Danio rerio OX=7955 GN=im:7148357 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF13771 zf-HC5HC2H	5.8e-05	34.6	PHD-like zinc-binding domain
2	PF13832 zf-HC5HC2H_2	0.00065	31.2	PHD-zinc-finger like domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000352463

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000426503	0.851	E3 ubiquitin-protein ligase RNF4
2	9606.ENSP00000363822	0.841	Androgen receptor
3	9606.ENSP00000385795	0.760	PHD finger protein 14
4	9606.ENSP00000323074	0.746	Retinoic acid-induced protein 1
5	9606.ENSP00000357644	0.716	Transcriptional repressor p66-beta
6	9606.ENSP00000378830	0.711	Glutamine-rich protein 1
7	9606.ENSP00000365588	0.704	Mediator of DNA damage checkpoint protein 1
8	9606.ENSP00000369666	0.698	F-box/LRR-repeat protein 19
9	9606.ENSP00000362354	0.648	Phosphatidate phosphatase LPIN3
10	9606.ENSP00000378402	0.631	Paired amphipathic helix protein Sin3a
11	9606.ENSP00000353463	0.622	Transcriptional repressor p66-alpha
12	9606.ENSP00000277540	0.616	Diphthine methyltransferase
13	9606.ENSP00000221973	0.610	Lens intrinsic membrane protein 2
14	9606.ENSP00000302327	0.588	Pygopus homolog 1
15	9606.ENSP00000244537	0.572	Histone cluster 1 H4 family member f
16	9606.ENSP00000261883	0.566	Cartilage intermediate layer protein 1
17	9606.ENSP00000371133	0.557	High mobility group protein 20A
18	9606.ENSP00000299855	0.554	Stromelysin-1
19	9606.ENSP00000344546	0.543	AT-rich interactive domain-containing protein 1B
20	9606.ENSP00000268712	0.534	Nuclear receptor corepressor 1

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0003723	0.997	RNA binding
GO:0003677	0.691	DNA binding
GO:0003824	0.616	catalytic activity
GO:0140110	0.407	transcription regulator activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0050789	0.986	regulation of biological process
GO:0050794	0.983	regulation of cellular process
GO:0006357	0.972	regulation of transcription by RNA polymerase II
GO:0048518	0.952	positive regulation of biological process
GO:0031325	0.939	positive regulation of cellular metabolic process
GO:0051173	0.934	positive regulation of nitrogen compound metabolic process
GO:0010604	0.931	positive regulation of macromolecule metabolic process
GO:0045935	0.881	positive regulation of nucleobase-containing compound metabolic process
GO:0010557	0.848	positive regulation of macromolecule biosynthetic process
GO:0045893	0.838	positive regulation of DNA-templated transcription
GO:0009987	0.809	cellular process
GO:0045944	0.541	positive regulation of transcription by RNA polymerase II
GO:0008152	0.489	metabolic process
GO:0071704	0.422	organic substance metabolic process
GO:0050896	0.339	response to stimulus
GO:0044238	0.315	primary metabolic process
GO:0006807	0.301	nitrogen compound metabolic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0016604	0.996	nuclear body
GO:0005737	0.731	cytoplasm
GO:0032991	0.593	protein-containing complex

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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