StarFunc result for job id Q9UII2

User Input

>input (106 residues)
MAVTALAARTWLGVWGVRTMQARGFGSDQSENVDRGAGSIREAGGAFGKREQAEEERYFR
AQSREQLAALKKHHEEEIVHHKKEIERLQKEIERHKQKIKMLKHDD

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q9UII2	1.000	1.000	2.495E-15	106	1.000	1.000	Q9UII2.pdb.gz	ATIF1_HUMAN ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1
2	AFDB:Q03344	0.719	0.714	6.677E-11	107	0.745	0.738	Q03344.pdb.gz	ATIF1_RAT ATPase inhibitor, mitochondrial OS=Rattus norvegicus OX=10116 GN=Atp5if1 PE=3 SV=2
3	AFDB:O35143	0.723	0.723	1.256E-10	106	0.679	0.679	O35143.pdb.gz	ATIF1_MOUSE ATPase inhibitor, mitochondrial OS=Mus musculus OX=10090 GN=Atp5if1 PE=1 SV=2
4	AFDB:P01096	0.706	0.687	2.314E-8	109	0.745	0.725	P01096.pdb.gz	ATIF1_BOVIN ATPase inhibitor, mitochondrial OS=Bos taurus OX=9913 GN=ATP5IF1 PE=1 SV=2
5	AFDB:P01098	0.302	0.354	1.140E-1	86	0.302	0.372	P01098.pdb.gz	STF1_YEAST F(1)-ATPase inhibitor STF1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=STF1 PE=1 SV=2
6	AFDB:O74523	0.321	0.370	3.448E-1	90	0.208	0.244	O74523.pdb.gz	ATIF_SCHPO Putative ATPase inhibitor, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=inh1 PE=3 SV=1
7	AFDB:Q22835	0.293	0.189	1.961	165	0.217	0.139	Q22835.pdb.gz	ZIP10_CAEEL Transcription factor zip-10 OS=Caenorhabditis elegans OX=6239 GN=zip-10 PE=1 SV=1
8	AFDB:Q925I1	0.476	0.104	1.961	591	0.217	0.039	Q925I1.pdb.gz	ATAD3_MOUSE ATPase family AAA domain-containing protein 3 OS=Mus musculus OX=10090 GN=Atad3 PE=1 SV=1
9	AFDB:O01395	0.242	0.110	2.691	275	0.264	0.102	O01395.pdb.gz	MST3_DROHY Axoneme-associated protein mst101(3) OS=Drosophila hydei OX=7224 GN=mst101(3) PE=2 SV=1
10	AFDB:Q7XJ96	0.477	0.121	3.691	471	0.179	0.040	Q7XJ96.pdb.gz	DRC4_CHLRE Dynein regulatory complex subunit 4 OS=Chlamydomonas reinhardtii OX=3055 GN=DRC4 PE=1 SV=1
11	PDB:7wtwt	0.327	0.321	5.862	108	0.104	0.102	7wtwt.pdb.gz	The nucleoplasmic phase of pre-40S formation prior to nuclear export.
12	PDB:7abgv	0.312	0.280	7.430	119	0.113	0.101	7abgv.pdb.gz	Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q9UII2	1.67e-72	212	106	1.000	1.000	ATIF1_HUMAN ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1
2	Q03344	4.42e-52	160	107	0.745	0.738	ATIF1_RAT ATPase inhibitor, mitochondrial OS=Rattus norvegicus OX=10116 GN=Atp5if1 PE=3 SV=2
3	O35143	6.89e-48	150	106	0.679	0.679	ATIF1_MOUSE ATPase inhibitor, mitochondrial OS=Mus musculus OX=10090 GN=Atp5if1 PE=1 SV=2
4	P01096	2.11e-42	136	109	0.642	0.624	ATIF1_BOVIN ATPase inhibitor, mitochondrial OS=Bos taurus OX=9913 GN=ATP5IF1 PE=1 SV=2
5	A3KNL5	5.51e-26	94.7	105	0.453	0.457	ATF1A_DANRE ATPase inhibitor A, mitochondrial OS=Danio rerio OX=7955 GN=atp5if1a PE=3 SV=1
6	Q1LYB6	4.47e-21	82.4	107	0.387	0.383	ATF1B_DANRE ATPase inhibitor B, mitochondrial OS=Danio rerio OX=7955 GN=atp5if1b PE=3 SV=1
7	O44441	5.02e-12	59.3	109	0.283	0.275	ATIF2_CAEEL ATPase inhibitor mai-2, mitochondrial OS=Caenorhabditis elegans OX=6239 GN=mai-2 PE=3 SV=1
8	P37209	1.19e-07	47.8	88	0.245	0.295	ATIF1_CAEEL ATPase inhibitor mai-1, mitochondrial OS=Caenorhabditis elegans OX=6239 GN=mai-1 PE=3 SV=1
9	Q0E8X8	1.20e-07	48.1	107	0.274	0.271	Q0E8X8_DROME FI01416p OS=Drosophila melanogaster OX=7227 GN=BcDNA:RE33866 PE=1 SV=1
10	Q8SYU1	2.74e-05	42.0	109	0.245	0.239	Q8SYU1_DROME RE33866p OS=Drosophila melanogaster OX=7227 GN=CG13551 PE=2 SV=1
11	P01098	4.55e-04	38.1	86	0.208	0.256	STF1_YEAST F(1)-ATPase inhibitor STF1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=STF1 PE=1 SV=2
12	P01097	0.016	34.3	85	0.217	0.271	ATIF_YEAST F(1)-ATPase inhibitor IF(1), mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=INH1 PE=1 SV=2
13	Q558Z2	0.063	33.9	905	0.189	0.022	SUN1_DICDI Sun domain-containing protein 1 OS=Dictyostelium discoideum OX=44689 GN=sun1 PE=1 SV=1
14	Q99K90	0.11	33.1	693	0.123	0.019	TAB2_MOUSE TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 OS=Mus musculus OX=10090 GN=Tab2 PE=1 SV=1
15	Q5U303	0.12	33.1	693	0.123	0.019	TAB2_RAT TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 OS=Rattus norvegicus OX=10116 GN=Tab2 PE=2 SV=2
16	Q9NYJ8	0.18	32.7	693	0.123	0.019	TAB2_HUMAN TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 OS=Homo sapiens OX=9606 GN=TAB2 PE=1 SV=1
17	Q9DGG9	0.34	32.0	2179	0.264	0.013	Q9DGG9_DANRE Myosin VIIA OS=Danio rerio OX=7955 GN=myo7A PE=2 SV=1
18	A0A0R4IAH0	0.55	31.2	1052	0.160	0.016	A0A0R4IAH0_DANRE Histone deacetylase OS=Danio rerio OX=7955 GN=wu:fa96d08 PE=1 SV=1
19	B4LLX1	0.76	30.0	107	0.217	0.215	B4LLX1_DROVI ATPase inhibitor mai-2, mitochondrial OS=Drosophila virilis OX=7244 GN=Dvir\GJ19999 PE=3 SV=1
20	Q99P99	0.90	30.8	1077	0.189	0.019	HDAC4_RAT Histone deacetylase 4 OS=Rattus norvegicus OX=10116 GN=Hdac4 PE=1 SV=2

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF05262 Borrelia_P83	3.6e+02	11.0	Borrelia P83/100 protein
2	PF06657 Cep57_MT_bd	42	16.0	Centrosome microtubule-binding domain of Cep57
3	PF04977 DivIC	71	14.6	Septum formation initiator
4	PF14362 DUF4407	1.9e+02	12.7	Domain of unknown function (DUF4407)
5	PF17253 DUF5320	1e+02	15.5	Family of unknown function (DUF5320)
6	PF08702 Fib_alpha	9.4	17.8	Fibrinogen alpha/beta chain family
7	PF04568 IATP	3.9e-13	61.0	Mitochondrial ATPase inhibitor, IATP
8	PF03245 Phage_lysis	32	16.1	Bacteriophage Rz lysis protein

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000335203

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000215375	0.948	ATP synthase subunit delta, mitochondrial
2	9606.ENSP00000243997	0.880	ATP synthase subunit epsilon, mitochondrial
3	9606.ENSP00000262030	0.855	ATP synthase subunit beta, mitochondrial
4	9606.ENSP00000358737	0.816	ATP synthase F(0) complex subunit B1, mitochondrial
5	9606.ENSP00000349142	0.815	ATP synthase subunit gamma, mitochondrial
6	9606.ENSP00000381736	0.815	ATP synthase subunit alpha, mitochondrial
7	9606.ENSP00000290299	0.768	ATP synthase subunit O, mitochondrial
8	9606.ENSP00000258424	0.755	Cytochrome c oxidase subunit 5B, mitochondrial
9	9606.ENSP00000355265	0.748	ATP synthase protein 8
10	9606.ENSP00000467262	0.745	Cytochrome b-c1 complex subunit 10
11	9606.ENSP00000306003	0.744	ATP synthase subunit e, mitochondrial
12	9606.ENSP00000367939	0.736	Cytochrome b-c1 complex subunit 8
13	9606.ENSP00000301587	0.721	ATP synthase subunit d, mitochondrial
14	9606.ENSP00000251453	0.707	Ribosomal protein S16
15	9606.ENSP00000299166	0.704	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
16	9606.ENSP00000358840	0.702	Up-regulated during skeletal muscle growth protein 5
17	9606.ENSP00000418842	0.701	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
18	9606.ENSP00000389649	0.696	ATP synthase-coupling factor 6, mitochondrial
19	9606.ENSP00000411788	0.684	G-protein coupled receptor 35
20	9606.ENSP00000305692	0.681	Lysosomal alpha-glucosidase

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0051117	0.999	ATPase binding
GO:0042030	0.999	ATPase inhibitor activity
GO:0042803	0.997	protein homodimerization activity
GO:0044877	0.960	protein-containing complex binding
GO:0004857	0.951	enzyme inhibitor activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.988	cellular process
GO:0044237	0.980	cellular metabolic process
GO:0065007	0.956	biological regulation
GO:0071704	0.948	organic substance metabolic process
GO:0006807	0.932	nitrogen compound metabolic process
GO:1901564	0.912	organonitrogen compound metabolic process
GO:1901566	0.871	organonitrogen compound biosynthetic process
GO:0044271	0.868	cellular nitrogen compound biosynthetic process
GO:1901360	0.806	organic cyclic compound metabolic process
GO:0006725	0.719	cellular aromatic compound metabolic process
GO:0046483	0.716	heterocycle metabolic process
GO:0050789	0.695	regulation of biological process
GO:0019438	0.662	aromatic compound biosynthetic process
GO:0018130	0.662	heterocycle biosynthetic process
GO:1901362	0.644	organic cyclic compound biosynthetic process
GO:0032501	0.584	multicellular organismal process
GO:0050794	0.560	regulation of cellular process
GO:0071840	0.538	cellular component organization or biogenesis
GO:0016043	0.489	cellular component organization
GO:0065009	0.429	regulation of molecular function
GO:0032502	0.410	developmental process
GO:0048856	0.381	anatomical structure development
GO:0048518	0.301	positive regulation of biological process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005739	1.000	mitochondrion
GO:0016020	0.971	membrane
GO:0032991	0.967	protein-containing complex
GO:0031090	0.907	organelle membrane
GO:0031967	0.905	organelle envelope
GO:0005740	0.883	mitochondrial envelope
GO:0031966	0.855	mitochondrial membrane
GO:0005743	0.844	mitochondrial inner membrane
GO:0098798	0.835	mitochondrial protein-containing complex
GO:0098800	0.832	inner mitochondrial membrane protein complex
GO:1902494	0.826	catalytic complex
GO:0005753	0.640	mitochondrial proton-transporting ATP synthase complex
GO:0009986	0.600	cell surface

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

[back to server]