StarFunc result for job id Q9Y3T9

User Input

>input (749 residues)
MAAAGSRKRRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSAS
RRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEA
SEEEDGAEEGEDGDRVPRGLKGKKNSVPVTVAMVERWKQAAKQRLTPKLFHEVVQAFRAA
VATTRGDQESAEANKFQVTDSAAFNALVTFCIRDLIGCLQKLLFGKVAKDSSRMLQPSSS
PLWGKLRVDIKAYLGSAIQLVSCLSETTVLAAVLRHISVLVPCFLTFPKQCRMLLKRMVI
VWSTGEESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPGALPFISFMQW
TLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKKETYQSVYNWQYVHCLFLWCRVLS
TAGPSEALQPLVYPLAQVIIGCIKLIPTARFYPLRMHCIRALTLLSGSSGAFIPVLPFIL
EMFQQVDFNRKPGRMSSKPINFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHC
IGFPELVLPVVLQLKSFLRECKVANYCRQVQQLLGKVQENSAYICSRRQRVSFGVSEQQA
VEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDED
RKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDA
EAGLAPGELQQLAQGPEDELEDLQLSEDD

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q9Y3T9	1.000	1.000	5.439E-87	749	1.000	1.000	Q9Y3T9.pdb.gz	NOC2L_HUMAN Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4
2	AFDB:Q9P7G0	0.637	0.673	4.097E-28	707	0.250	0.264	Q9P7G0.pdb.gz	YKY4_SCHPO Uncharacterized NOC2 family protein C1142.04 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC1142.04 PE=1 SV=1
3	AFDB:P39744	0.633	0.665	4.989E-28	710	0.255	0.269	P39744.pdb.gz	NOC2_YEAST Nucleolar complex protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=NOC2 PE=1 SV=2
4	AFDB:Q9ZPV5	0.614	0.602	1.692E-27	764	0.247	0.242	Q9ZPV5.pdb.gz	NOC2_ARATH Nucleolar complex-associated protein 2 OS=Arabidopsis thaliana OX=3702 GN=NOC2 PE=1 SV=2
5	AFDB:Q389A0	0.591	0.676	4.319E-22	649	0.200	0.231	Q389A0.pdb.gz	Q389A0_TRYB2 Nucleolar complex protein 2 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.389.1290 PE=3 SV=1
6	AFDB:Q0WVH0	0.586	0.730	2.052E-20	594	0.170	0.214	Q0WVH0.pdb.gz	RBLOT_ARATH Protein REBELOTE OS=Arabidopsis thaliana OX=3702 GN=RBL PE=1 SV=1
7	AFDB:O13874	0.427	0.587	3.532E-15	528	0.148	0.210	O13874.pdb.gz	YE19_SCHPO Uncharacterized NOC2 family protein C1B3.09c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC1B3.09c PE=3 SV=1
8	PDB:7r6k8	0.471	0.750	4.242E-15	458	0.182	0.297	7r6k8.pdb.gz	Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
9	PDB:6q82A	0.199	0.159	1.187E-3	1027	0.092	0.067	6q82A.pdb.gz	Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
10	PDB:3w3uA	0.268	0.209	2.509E-3	1030	0.089	0.065	3w3uA.pdb.gz
11	PDB:6l4oA	0.242	0.358	2.610E-3	429	0.065	0.114	6l4oA.pdb.gz
12	AFDB:Q9S791	0.122	0.142	2.978E-3	610	0.111	0.136	Q9S791.pdb.gz	Q9S791_ARATH AT1G70770 protein OS=Arabidopsis thaliana OX=3702 GN=F15H11.2 PE=1 SV=1
13	AFDB:F4I4N4	0.130	0.148	3.352E-3	615	0.108	0.132	F4I4N4.pdb.gz	F4I4N4_ARATH Uncharacterized protein OS=Arabidopsis thaliana OX=3702 GN=At1g23170 PE=1 SV=1
14	PDB:7cunG	0.161	0.142	3.870E-3	895	0.096	0.080	7cunG.pdb.gz	Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
15	PDB:1qgkA	0.148	0.131	5.099E-3	876	0.107	0.091	1qgkA.pdb.gz
16	PDB:3gniA	0.222	0.412	6.459E-3	335	0.067	0.149	3gniA.pdb.gz	ATP and MO25alpha regulate the conformational state of the STRADalpha pseudokinase and activation of the LKB1 tumour suppressor
17	AFDB:B5X0I6	0.101	0.082	7.086E-3	1091	0.120	0.082	B5X0I6.pdb.gz	VIP6_ARATH Protein CTR9 homolog OS=Arabidopsis thaliana OX=3702 GN=VIP6 PE=1 SV=1
18	PDB:5wlcST	0.283	0.343	8.182E-3	599	0.092	0.115	5wlcST.pdb.gz	The complete structure of the small-subunit processome.
19	PDB:4r0zA	0.187	0.230	1.121E-2	557	0.080	0.108	4r0zA.pdb.gz
20	PDB:7unkA	0.205	0.160	1.121E-2	1047	0.104	0.074	7unkA.pdb.gz

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q9Y3T9	0.0	1541	749	1.000	1.000	NOC2L_HUMAN Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4
2	Q59M49	2.86e-96	316	714	0.270	0.283	Q59M49_CANAL mRNA-binding ribosome synthesis protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=NOC2 PE=3 SV=1
3	P39744	2.23e-94	311	710	0.243	0.256	NOC2_YEAST Nucleolar complex protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=NOC2 PE=1 SV=2
4	Q9ZPV5	3.78e-86	290	764	0.218	0.213	NOC2_ARATH Nucleolar complex-associated protein 2 OS=Arabidopsis thaliana OX=3702 GN=NOC2 PE=1 SV=2
5	Q9P7G0	8.59e-86	288	707	0.254	0.269	YKY4_SCHPO Uncharacterized NOC2 family protein C1142.04 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC1142.04 PE=1 SV=1
6	Q0WVH0	2.53e-43	167	594	0.155	0.195	RBLOT_ARATH Protein REBELOTE OS=Arabidopsis thaliana OX=3702 GN=RBL PE=1 SV=1
7	Q389A0	2.30e-38	154	649	0.134	0.154	Q389A0_TRYB2 Nucleolar complex protein 2 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.389.1290 PE=3 SV=1
8	O13874	1.59e-28	122	528	0.107	0.152	YE19_SCHPO Uncharacterized NOC2 family protein C1B3.09c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC1B3.09c PE=3 SV=1
9	Q9BHK7	2.1	34.3	1591	0.049	0.023	Q9BHK7_CAEEL 5'-3' exoribonuclease 1 OS=Caenorhabditis elegans OX=6239 GN=xrn-1 PE=1 SV=3
10	P13834	5.8	32.7	735	0.045	0.046	GYS1_RABIT Glycogen [starch] synthase, muscle OS=Oryctolagus cuniculus OX=9986 GN=GYS1 PE=1 SV=4
11	Q12019	8.9	32.3	4910	0.048	0.007	MDN1_YEAST Midasin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MDN1 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF15677 CEND1	19	17.2	Cell cycle exit and neuronal differentiation protein 1
2	PF03715 Noc2	1.3e-115	397.3	Noc2p family

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000317992

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000234170	0.999	CCAAT/enhancer-binding protein zeta
2	9606.ENSP00000346725	0.995	Pescadillo homolog
3	9606.ENSP00000455106	0.995	Ribosome biogenesis protein BOP1
4	9606.ENSP00000297990	0.994	Nucleolar protein 6
5	9606.ENSP00000285814	0.992	Nucleolar protein interacting with the FHA domain of MKI67
6	9606.ENSP00000402338	0.992	Ribosome production factor 2 homolog
7	9606.ENSP00000407323	0.992	Probable rRNA-processing protein EBP2
8	9606.ENSP00000253237	0.990	Glutamate-rich WD repeat-containing protein 1
9	9606.ENSP00000483484	0.990	Ribosome biogenesis protein NSA2 homolog
10	9606.ENSP00000360412	0.989	Nucleolar complex protein 3 homolog
11	9606.ENSP00000454836	0.989	Transducin beta-like protein 3
12	9606.ENSP00000358812	0.988	Protein RRP5 homolog
13	9606.ENSP00000364320	0.988	mRNA turnover protein 4 homolog
14	9606.ENSP00000396673	0.987	pre-rRNA processing protein FTSJ3
15	9606.ENSP00000322396	0.986	Ribosome biogenesis regulatory protein homolog
16	9606.ENSP00000354040	0.986	Nucleolar GTP-binding protein 1
17	9606.ENSP00000423067	0.985	WD repeat-containing protein 36
18	9606.ENSP00000371858	0.983	Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase
19	9606.ENSP00000348596	0.981	Protein SDA1 homolog
20	9606.ENSP00000221801	0.979	rRNA 2'-O-methyltransferase fibrillarin

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0042393	1.000	histone binding
GO:0003714	1.000	transcription corepressor activity
GO:0140297	1.000	DNA-binding transcription factor binding
GO:0031491	1.000	nucleosome binding
GO:0003723	1.000	RNA binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.986	cellular process
GO:0050794	0.986	regulation of cellular process
GO:0080090	0.966	regulation of primary metabolic process
GO:0060255	0.961	regulation of macromolecule metabolic process
GO:0051171	0.956	regulation of nitrogen compound metabolic process
GO:0031323	0.956	regulation of cellular metabolic process
GO:0010468	0.954	regulation of gene expression
GO:0010556	0.949	regulation of macromolecule biosynthetic process
GO:0048523	0.948	negative regulation of cellular process
GO:0031326	0.948	regulation of cellular biosynthetic process
GO:0051252	0.945	regulation of RNA metabolic process
GO:0071840	0.937	cellular component organization or biogenesis
GO:0009892	0.933	negative regulation of metabolic process
GO:0050896	0.932	response to stimulus
GO:0048518	0.925	positive regulation of biological process
GO:0006355	0.917	regulation of DNA-templated transcription
GO:0010941	0.906	regulation of cell death
GO:0042981	0.874	regulation of apoptotic process
GO:0009893	0.763	positive regulation of metabolic process
GO:0010604	0.686	positive regulation of macromolecule metabolic process
GO:0010605	0.636	negative regulation of macromolecule metabolic process
GO:0051172	0.630	negative regulation of nitrogen compound metabolic process
GO:0016043	0.503	cellular component organization
GO:0031324	0.469	negative regulation of cellular metabolic process
GO:0051246	0.449	regulation of protein metabolic process
GO:0048583	0.427	regulation of response to stimulus
GO:0010646	0.422	regulation of cell communication
GO:0051716	0.412	cellular response to stimulus
GO:0009890	0.385	negative regulation of biosynthetic process
GO:0031327	0.378	negative regulation of cellular biosynthetic process
GO:0010558	0.374	negative regulation of macromolecule biosynthetic process
GO:0045934	0.332	negative regulation of nucleobase-containing compound metabolic process
GO:0048522	0.317	positive regulation of cellular process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005654	1.000	nucleoplasm
GO:0005730	1.000	nucleolus
GO:0005829	0.998	cytosol
GO:0005694	0.920	chromosome

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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