StarFunc result for job id Q9Y520

User Input

>input (1400 residues)
MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTARHGLQSLGKVGISRRMPPPANL
PSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPPAQPKPGVAAPPEVAPAPKS
WASNKQGGQGDGIQVNSQFQQEFPSLQAAGDQEKKEKETNDDNYGPGPSLRPPNVACWRD
GGKAAGSPSSSDQDEKLPGQDESTAGTSEQNDILKVVEKRIACGPPQAKLNGQQAALASQ
YRAMMPPYMFQQYPRMTYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSAS
ELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASEN
NENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPP
DRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAA
CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQE
KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI
EPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVL
SGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQP
MQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSP
NSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQ
EQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPD
QKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPI
ERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPV
LRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPI
QPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEK
VISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSY
RGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQ
RGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEK
PYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQS
EVPKPEDGEPPRRHEQFIPI

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q7TPM1	0.050	0.048	1.815E-25	1486	0.266	0.250	Q7TPM1.pdb.gz	PRC2B_MOUSE Protein PRRC2B OS=Mus musculus OX=10090 GN=Prrc2b PE=1 SV=1
2	AFDB:P48634	0.069	0.048	1.343E-24	2157	0.325	0.211	P48634.pdb.gz	PRC2A_HUMAN Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3
3	AFDB:Q5JSZ5	0.049	0.036	2.555E-24	2229	0.286	0.180	Q5JSZ5.pdb.gz	PRC2B_HUMAN Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2
4	AFDB:P21263	0.054	0.042	2.115E-7	1893	0.163	0.120	P21263.pdb.gz	NEST_RAT Nestin OS=Rattus norvegicus OX=10116 GN=Nes PE=1 SV=2
5	AFDB:E2QD16	0.050	0.047	3.023E-7	1570	0.164	0.146	E2QD16.pdb.gz	E2QD16_DROME Non-specific lethal 1, isoform M OS=Drosophila melanogaster OX=7227 GN=nsl1 PE=1 SV=1
6	AFDB:Q1G7G9	0.043	0.042	2.580E-6	1523	0.150	0.138	Q1G7G9.pdb.gz	TALD3_CHICK TALPID3 protein OS=Gallus gallus OX=9031 GN=TALPID3 PE=2 SV=2
7	AFDB:Q9R0I7	0.061	0.062	8.698E-6	1386	0.146	0.147	Q9R0I7.pdb.gz	YLPM1_MOUSE YLP motif-containing protein 1 OS=Mus musculus OX=10090 GN=Ylpm1 PE=2 SV=2
8	AFDB:P48681	0.043	0.038	1.909E-5	1621	0.151	0.131	P48681.pdb.gz	NEST_HUMAN Nestin OS=Homo sapiens OX=9606 GN=NES PE=1 SV=2
9	AFDB:F1R405	0.038	0.035	5.991E-5	1573	0.159	0.142	F1R405.pdb.gz	F1R405_DANRE B-cell CLL/lymphoma 9 protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch73-15j19.1 PE=1 SV=1
10	AFDB:A0A0B4K682	0.062	0.065	1.413E-4	1315	0.124	0.132	A0A0B4K682.pdb.gz	A0A0B4K682_DROME Javelin-like, isoform D OS=Drosophila melanogaster OX=7227 GN=jvl PE=4 SV=1
11	PDB:5wlcST	0.045	0.092	9.077	599	0.014	0.032	5wlcST.pdb.gz	The complete structure of the small-subunit processome.
12	PDB:2k8pA	0.022	0.073	9.750	189	0.020	0.148	2k8pA.pdb.gz
13	PDB:6elzm	0.030	0.056	9.750	645	0.009	0.019	6elzm.pdb.gz	Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	E7EPN9	0.0	2841	2819	1.000	0.497	E7EPN9_HUMAN Proline rich coiled-coil 2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=1
2	Q3TLH4	0.0	1974	2846	0.824	0.405	PRC2C_MOUSE Protein PRRC2C OS=Mus musculus OX=10090 GN=Prrc2c PE=1 SV=3
3	Q9Y520	0.0	2847	2896	1.000	0.483	PRC2C_HUMAN Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4
4	A0A1U9X974	2.76e-82	301	2157	0.175	0.114	A0A1U9X974_HUMAN PRRC2A OS=Homo sapiens OX=9606 PE=4 SV=1
5	P48634	2.76e-82	301	2157	0.175	0.114	PRC2A_HUMAN Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3
6	Q5JSZ5	5.49e-50	197	2229	0.155	0.097	PRC2B_HUMAN Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2
7	Q7TPM1	7.24e-46	184	1486	0.079	0.074	PRC2B_MOUSE Protein PRRC2B OS=Mus musculus OX=10090 GN=Prrc2b PE=1 SV=1
8	F1QBY1	9.74e-10	66.2	2876	0.038	0.018	NIPLB_DANRE Nipped-B-like protein B OS=Danio rerio OX=7955 GN=nipblb PE=2 SV=1
9	A8T6P4	2.53e-06	54.7	838	0.035	0.058	MYRIP_DANRE Rab effector MyRIP OS=Danio rerio OX=7955 GN=myrip PE=1 SV=1
10	Q9LFE0	4.81e-05	50.4	820	0.032	0.055	DOT2_ARATH SART-1 family protein DOT2 OS=Arabidopsis thaliana OX=3702 GN=DOT2 PE=1 SV=1
11	Q4QRG7	1.90e-04	48.1	434	0.022	0.071	Q4QRG7_DANRE RNA-binding motif protein, X-linked 2 OS=Danio rerio OX=7955 GN=zgc:113884 PE=2 SV=1
12	Q15811	5.64e-04	47.0	1721	0.042	0.034	ITSN1_HUMAN Intersectin-1 OS=Homo sapiens OX=9606 GN=ITSN1 PE=1 SV=3
13	Q1WWC9	6.34e-04	47.0	1096	0.021	0.027	Q1WWC9_DROME Dynamin associated protein 160, isoform C OS=Drosophila melanogaster OX=7227 GN=Dap160 PE=1 SV=1
14	F8W7U0	6.96e-04	46.6	1149	0.042	0.051	F8W7U0_HUMAN Intersectin 1 OS=Homo sapiens OX=9606 GN=ITSN1 PE=1 SV=1
15	M9PBF6	7.37e-04	46.6	1088	0.021	0.028	M9PBF6_DROME Dynamin associated protein 160, isoform G OS=Drosophila melanogaster OX=7227 GN=Dap160 PE=1 SV=1
16	O61618	7.51e-04	46.6	1094	0.021	0.027	O61618_DROME Dynamin associated protein isoform Dap160-1 OS=Drosophila melanogaster OX=7227 GN=Dap160 PE=2 SV=1
17	Q9VIF7	7.51e-04	46.6	1097	0.021	0.027	Q9VIF7_DROME Dynamin associated protein 160, isoform A OS=Drosophila melanogaster OX=7227 GN=Dap160 PE=1 SV=1
18	M9ND00	7.76e-04	46.6	1190	0.021	0.025	M9ND00_DROME Dynamin associated protein 160, isoform D OS=Drosophila melanogaster OX=7227 GN=Dap160 PE=1 SV=1
19	M9PDC7	8.10e-04	46.6	1005	0.021	0.030	M9PDC7_DROME Dynamin associated protein 160, isoform H OS=Drosophila melanogaster OX=7227 GN=Dap160 PE=1 SV=1
20	Q8INU2	8.39e-04	46.6	1014	0.021	0.030	Q8INU2_DROME Dynamin associated protein 160, isoform B OS=Drosophila melanogaster OX=7227 GN=Dap160 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF07001 BAT2_N	1.6e-46	170.7	BAT2 N-terminus

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000343629

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000307208	0.860	Nucleosome-remodeling factor subunit BPTF
2	9606.ENSP00000282516	0.847	Nipped-B-like protein
3	9606.ENSP00000436786	0.832	Histone-lysine N-methyltransferase 2A
4	9606.ENSP00000371307	0.772	Phospholipid phosphatase 6
5	9606.ENSP00000354920	0.733	Methyltransferase-like protein 13
6	9606.ENSP00000356702	0.726	Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
7	9606.ENSP00000037502	0.713	Myocilin
8	9606.ENSP00000454903	0.713	Uncharacterized protein C3orf84
9	9606.ENSP00000402515	0.682	Serine/threonine-protein kinase SMG1
10	9606.ENSP00000236192	0.666	Vesicle-associated membrane protein 4
11	9606.ENSP00000340648	0.666	E3 ubiquitin-protein ligase HUWE1
12	9606.ENSP00000386759	0.662	Histone-lysine N-methyltransferase SETD2
13	9606.ENSP00000282007	0.661	Zinc finger CCCH domain-containing protein 13
14	9606.ENSP00000275034	0.651	PH-interacting protein
15	9606.ENSP00000371393	0.649	Phosphoglucomutase-2
16	9606.ENSP00000438527	0.644	Zinc finger CCCH domain-containing protein 11A
17	9606.ENSP00000458075	0.643	BOLA2-SMG1P6 readthrough
18	9606.ENSP00000377681	0.619	Ras GTPase-activating protein-binding protein 1
19	9606.ENSP00000348984	0.615	Protein SON
20	9606.ENSP00000252998	0.600	RBBP8 N-terminal-like protein

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0003723	1.000	RNA binding
GO:0005515	0.997	protein binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

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[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.959	cellular process
GO:0034063	0.760	stress granule assembly
GO:0048856	0.540	anatomical structure development
GO:0065007	0.311	biological regulation

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005829	1.000	cytosol
GO:0016020	0.959	membrane

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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