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by zcx@umich.edu
Sun Nov 28, 2021 11:56 am
Forum: Main Forum
Topic: parsing TM-align output to report protein domain PAV and coords
Replies: 3
Views: 2841

Re: parsing TM-align output to report protein domain PAV and coords

[1] Pfam is not defined based on tertiary structures. To check if a protein sequence contains a pfam domain, you should use hmmsearch or hmmscan from HMMER to align the sequence and the HMM of the pfam family. TM-align can tell you whether your protein structure model is structurally similar to the ...