Alignment based on pLDDT

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antonia.feilden
Posts: 3
Joined: Wed Feb 21, 2024 10:12 am

Alignment based on pLDDT

Post by antonia.feilden »

To whom it may concern,

I have read: viewtopic.php?f=3&t=652&p=1220&hilit=pl ... fe7c#p1220

Does US-Align take into account pLDDT and BAT scores for AlphaFold and PDB crystal structures? Both are residue location confidence metrics. I believe this could enhance the tool and be implemented using the summation of relative weights of the aligned residues.

Best wishes,
Antonia