SEQ2FUN

FURNA

FURNA (Functions of RNAs) is a database of ligand-RNA interactions and Gene Ontology annotations for RNAs in the Protein Data Bank (PDB). Each entry in FURNA contains a comprehensive list of annotations on:

  • Ligand-binding sites;
  • Gene Ontology (GO) terms and Enzyme Commission (EC) numbers;
  • Rfam families;
  • Motifs for protein binding from the ATtRACT database;
  • Secondary structure assignments from CSSR and DSSR;
  • Cross reference to external databases, including RCSB PDB, PDBe, PDBj, PDBsum, NAKB, DNATCO, BGSU RNA, QuickGO, ChEMBL, DrugBank, ZINC, UniProt, PubMed, RNAcentral.

    Search name

    PDB ID
    PDB Chain ID
    Ligand ID
    Ligand name
    RNA name
    RNAcentral accession
    Rfam family
    Taxon
    EC number
    GO term
    ATtRACT motif
    PubMed ID
      

    Search sequence (quick search by BLAST)

    Paste your sequence here:     [Sample rna input] [Sample protein input] [Sample dna input]

    Select Sequence type:     RNA     Protein     DNA
      

    Search RNA sequence (sensitive search by Infernal)

    Paste your sequence here:     [Sample rna input]

      

    Search RNA structure (by US-align)

    Paste your structure here:     [Example file]

    Or upload PDB or mmCIF format file from your computer: (do not upload compressed file).
      

    • Reference:
  • Chengxin Zhang, Lydia Freddolino (2024) "FURNA: a database for function annotations of RNA structures," PLOS Biology 22(7): e3002476.