5mei	1	3149	3.5	RF02540,RF02543	URS000061F377_559292	28457705		0003735		0005840	559292	uugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaauaagcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagcggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaauuuggagagggcaacuuuggggccguuccuugucuauguuccuuggaacaggacgucauagagggugagaaucccguguggcgaggagugcgguucuuuguaaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugggugguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgugaaauuguugaaagggaagggcauuugaucagacaggccagcaucaguuuugguggcaggauaaauccauaggaauguagcuugccucgguaaguauuauagccugugggaauacugccagcugggacugaggacugcgacguaagucaaggaugcuggcauaaugguuauaugccgcccgucuugaaacacggaccaaggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcguaaugaaagugaacguagguuggggccucgcaagaggugcacaaucgaccgauccugaugucuucggauggauuugaguaagagcauagcuguugggacccgaaagauggugaacuaugccugaauagggugaagccagaggaaacucugguggaggcucguagcgguucugacgugcaaaucgaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucuaguagcugguuccugccgaaguuucccucaggauagcagaagcucguaucaguuuuaugagguaaagcgaaugauuagagguuccggggucgaaaugaccuugaccuauucucaaacuuuaaauauguaagaaguccuuguuacuuaauugaacguggacauuugaaugaagagcuuuuagugggccauuuuugguaagcagaacuggcgaugcgggaugaaccgaacguagaguuaaggugccggaauacacgcucaucagacaccacaaaagguguuaguucaucuagacagccggacgguggccauggaagucggaauccgcuaaggaguguguaacaacucaccggccgaaugaacuagcccugaaaauggauggcgcucaagcguguuaccuauacucuaccgucaggguugauaugaugcccugacgaguaggcaggcguggaggucagugacgaagccuagaccguaaggucgggucgaacggccucuagugcagaucuuggugguaguagcaaauauucaaaugagaacuuugaagacugaaguggggaaagguuccacgucaacagcaguuggacguggguuagucgauccuaagagauggggaagcuccguuucaaaggccugauuuuaugcaggccaccaucgaaagggaauccgguuaagauuccggaaccuggauauggauucuucacgguaacguaacugaauguggagacgucggcgcgagcccugggaggaguuaucuuuucuucuuaacagcuuaucaccccggaauugguuuauccggagauggggucuuauggcuggaagaggccagcaccuuugcuggcuccggugcgcuugugacggcccgugaaaauccacaggaaggaauaguuuucaugccaggucguacugauaaccgcagcaggucuccaaggugaacagccucuaguugauagaauaauguagauaagggaagucggcaaaauagauccguaacuucgggauaaggauuggcucuaagggucggguacgaucaacuuagaacugguacggacaaggggaaucugacugucuaauuaaaacauagcauugcgauggucagaaagugauguugacgcaaugugauuucugcccagugcucugaaugucaaagugaagaaauucaaccaagcgcggguaaacggcgggaguaacuaugacucucuuaagguagccaaaugccucgucaucuaauuagugacgcgcaugaauggauuaacgagauucccacugucccuaucuacuaucuagcgaaaccacagccaagggaacgggcuuggcagaaucagcggggaaagaagacccuguugagcuugacucuaguuugacauugugaagagacauaguuucuuuacuuauucaaugaagcggagcuggaauucauuuuccacguucuagcauucaaggucccauucggggcugauccggguugaagacauugucagguggggaguuuggcuggggcggcacaucuguuaaacgauaacgcagauguccuaaggggggcucauggagaacagaaaucuccaguagaacaaaaggguaaaagcccccuugauuuugauuuucagugugaauacaaaccaugaaaguguggccuaucgauccuuuagucccucggaauuugaggcuagaggugccagaaaaguuaccacagggauaacuggcuuguggcagucaagcguucauagcgacauugcuuuuugauucuucgaugucggcucuuccuaucauaccgaagcagaauucgguaagcguuggauuguucacccacuaauagggaacgugagcuggguuuagaccgucgugagacagguuaguuuuacccuacugaugaauguuaccgcaauaguaauugaacuuaguacgagaggaacaguucauucggauaauugguuuuugcggcugucugaucaggcauugccgcgaagcuaccauccgcuggauuauggcugaacgccucuaagucagaauccaugcuagaacgcggugauuucuuugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucgcugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggugcuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuuguauacgacuuagauguacaacgggguauuguaagcaguagaguagccuuguuguuacgaucugcugagauuaagccuuuguugucugauuugu	........................<<<<<<.....<......>......>>>>>.>.........<<....>>..<<<<<......<<.....>>.....>>>>>..[[[..<<.......<<.<<<<<<...>>>>>>.>>.......>>....<<<<<<<.<<<<<<<<<<<<<<<<<<<<.....<<<<......>>>>.(.......<<<......)>>>....>>>>>>>>..>>>>>>>>....>>>>>>>>>>>........<<<<<<<........>>>>>>>.....(((((..<<<<<<)))))..]]]..................................<<....>>...............<<<<....>>>>..................................<<<<<.<<<<<.<....<<<<<<<.<<<<<<<<<<<<<<<.....<<<<<<<<<......<<<<<<....>>>>>>.......>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<....>>>.....>>>>>>>....>>>>>>.>>>>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>...<<....>>.......<<<<<..<<<<<....>>>>>...>>>>>.<<<<<<<<....<....>....>>>.>>>.>>....>>>>>>.>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<..<<.<<........>>>>.>>>....>>>>>>>>>...<<.......>>......>>>>>>......>.>>..<<<<<<....<.<<<....>>>.><<<<<<<<<<...<<<.<<<<<<<.....<<<....<<<....<<<<...<<<<<<.....>>>>>>.>>>>....>>>..>.>>.....>>>>>...<<<<.<<<<.<......>>>>>.>>>>.....>>>>>.>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<..<<<<(((.....<<<<<<......<..........<<<.<<<<<<<<<<.......<<<<<.<<....<<.........>>....>>.........<<......>>...>>>>>...>>>>>>>>>>>>>..........))).>....>>>>>>.>>>>..>>>>>>><<<<<<<<<.........>>>>>>>>>....>>>>>><.<<<<<<<<.<<......<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<.....<<.....<<<<<<.......>>>>>><<<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<....<<<....>>>........<<<<<<........>>>>>>....>>....>>...<<<<<........>>>>>))<<<<.<<<<<<<.....<<<....>>>.......<<<<<<...<<<<.<<<<<<<.<<<<<<<<<<..{{{..>>>>>><...<<<<<....<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....><<<<<<<<....>>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>..........>>>..>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.....>>>>.>>>>>..<<<<.....<<<<<<<.<<...............<<<<<...............>>>>><<.<<<<<<<<<<......>>>>..>>>>>>.>>............<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.<...<<.....<<<<....>>>>.....>>.>>>>>..>>>>><<<<<<.......>>>>>>........<...........<<<<<.......>>>>>.....>.....>>....>>.>>>>>>>.....>>.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>....[[[[[..{{{.{{......[[[[.{{[[[[..<<<<<.<<<<<<<<..<<<<<<<<<.....>>>>>>>>>...<<<<<.....<<<<..<<<<<......>>>>>...............<<<<<<....>>>>>>..>>>>..>>>>>.....>>>>>>>>..>>>>>...<<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...<<<.<<<<<.......>>>>.>>>>.<<<....>>>.>>))).......((((((..((((.>>>>>>))))))))))..........]]]]..}}]]]].......<<.<...<<<<<<...<<.......>>...>>>>>>....>.>.>.........<<<..<<<<<..<.<<<<<<<......>>>>>>>...>.<<<.........>>>.....>>>>>......>>>.......<<<<<<<....>>>.>>>>....}}..}}}.]]]]]....<<<<<<<<..<<<<...<<<<<<...............>>>>>>..<<<<<...<<<<....<<<<<<<<<<}}}.>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>>.......<<<<<..<<<.<<....<<..........<<<<<<.....>>>>>>......>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>>>>.>>>>>>.............>>.>>>..>>>>>..<<<<<.....................<<<<<<<<<.<<<....<<<<....<<<<........>>>>...>>>>...>>>....>>>>.>>>>>..>>>>>..	........................(((((......(...[..).......)))).).........((....))...((((......((.]...)).....))))...((((.........(((.((((((...)))))).))....)........((((((.(((((((.(((((((((((((...({((((......)))))[[(...).(((....}]])))....))))))))..))))).))....)))))))))))...)....(((((((........))))))).....(((((..[[[[[[)))))..)))..................................((....))............(..((((....))))............).....................(((((.((((((.....(((((((((((((((((((((((.......(((((((......((((........)))).......))))))).....))))).))))))))))........(((....)))....))))))))....)))))).))))).[((((........))))((((((....((((((.((((((..(((...(((.......)))...)))...((....)).......(((((..(((((....)))))...))))).((((((((....(....)....))).))).))....)))))).))))))..((.(...((((((.....(((((((((..((((...(((((((....)))))))...)[)))...(((..((.((.......<)))).)))....))))))))).(.((.......))...)..))))))......).))..((((((....(.(((....))).)((((((((((...(((.(((((((.....(((....(((..(.((((...((.(((.....))).)).)))).)..)))..)).).....)))))...((((.((((.(......))))).)))).....))))).)))))))).))..((((.(((((.....))))).))))....(((......)))...(((((((...((([[[...(.((((((......(..........(((.((((((((((.....{.(((((..((....(.........)....))......(...(........).).)))))...)))))))))))))..........]]].)....))))))))))...)))))))(((((((((.........)))))))))....))))))(.((((((((.((......((((.((((....))))))))...))))))))))..).....))))))((.....((.....((((((.......))))))((((.....((((..((...(((((....((.....))..)))))....[[(((.((...((....(((....)))........(..................)....))....))...(((((........)))))]]((((.((((((((...((((....)))...(.<.((((((...((((.((((((((((((((((((...{{..))))))(...(((((....(((((.....(((.....))).....))))).....)))))....)(((((((......))))))))))).).))))))).))))(...)....))))))...))....))))..)))))))).)))..)).....((......)).)))).((((.....))))..))))..((((.....(((((((.((..(....(.......(((((....(.{..).....)))))((.((((((((((.(...)))))..)))))).))(...).......(((((((((.].((.........))...(((((((....((((.....))))......))))))).}.(((.(((..((((((.(...((.....((((....)))).....)).)))))..)))))(((((.........)))))........((..........(((((.......)))))..)..)....)))....)).))))))).)..))).)))))))..))))))....)).{..(((((.....]}.)))))....(((((..(((.((......((((.((((((..(((((.((((((((..(((((((.........)))))))....((((.....((((..((((........))))...........>...((((((....))))))..))))..))))......))))))))..)))))..(((......[)).)((((((..........]))))))([((...(((((((.(.((((((.......))))))...).((][.[[[))....)))))))...(((..((((....{..))))..))).(((....))).))]]].].....((((((..((((.]]]]]]))))))))))....)}....))))..)))))).......((.(.(.((((((...((.......))...))))))...)).).)........((((.((((((..(.(((((((......))))))..).).(((.(.....).))).....)))))..)...))).).....(((((((....))).))))..>.))..))).)))))....((((((((..((((.(.(((((......(....).....))))).)(((((...((((....((((((((((}}..)))))..)))))...))))..))))).((((...((((.....}.......))))...)))).))))....)))))))).......((((...(((.((....((.(........(((((((..).)))))).....))).......((((((...(((((.(..(((......)))..).))))).)))))).............)).)))...))))..(((((.(..(.......)..).....(((((((((.(((....((((.(..(...((..)..)...)..)))))...)))....)))).)))))..)))))..	Crystal structure of Agelastatin A bound to the 80S ribosome; 25S ribosomal RNA
5mei	AR	3149	3.5	RF02540,RF02543	URS000061F377_559292	28457705		0003735		0005840	559292	uugaccucaaaucagguaggaguacccgcugaacuuaagcauaucaauaagcggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagcggcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaauuuggagagggcaacuuuggggccguuccuugucuauguuccuuggaacaggacgucauagagggugagaaucccguguggcgaggagugcgguucuuuguaaagugccuucgaagagucgaguuguuugggaaugcagcucuaagugggugguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgugaaauuguugaaagggaagggcauuugaucagacaggccagcaucaguuuugguggcaggauaaauccauaggaauguagcuugccucgguaaguauuauagccugugggaauacugccagcugggacugaggacugcgacguaagucaaggaugcuggcauaaugguuauaugccgcccgucuugaaacacggaccaaggagucuaacgucuaugcgaguguuuggguguaaaacccauacgcguaaugaaagugaacguagguuggggccucgcaagaggugcacaaucgaccgauccugaugucuucggauggauuugaguaagagcauagcuguugggacccgaaagauggugaacuaugccugaauagggugaagccagaggaaacucugguggaggcucguagcgguucugacgugcaaaucgaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucuaguagcugguuccugccgaaguuucccucaggauagcagaagcucguaucaguuuuaugagguaaagcgaaugauuagagguuccggggucgaaaugaccuugaccuauucucaaacuuuaaauauguaagaaguccuuguuacuuaauugaacguggacauuugaaugaagagcuuuuagugggccauuuuugguaagcagaacuggcgaugcgggaugaaccgaacguagaguuaaggugccggaauacacgcucaucagacaccacaaaagguguuaguucaucuagacagccggacgguggccauggaagucggaauccgcuaaggaguguguaacaacucaccggccgaaugaacuagcccugaaaauggauggcgcucaagcguguuaccuauacucuaccgucaggguugauaugaugcccugacgaguaggcaggcguggaggucagugacgaagccuagaccguaaggucgggucgaacggccucuagugcagaucuuggugguaguagcaaauauucaaaugagaacuuugaagacugaaguggggaaagguuccacgucaacagcaguuggacguggguuagucgauccuaagagauggggaagcuccguuucaaaggccugauuuuaugcaggccaccaucgaaagggaauccgguuaagauuccggaaccuggauauggauucuucacgguaacguaacugaauguggagacgucggcgcgagcccugggaggaguuaucuuuucuucuuaacagcuuaucaccccggaauugguuuauccggagauggggucuuauggcuggaagaggccagcaccuuugcuggcuccggugcgcuugugacggcccgugaaaauccacaggaaggaauaguuuucaugccaggucguacugauaaccgcagcaggucuccaaggugaacagccucuaguugauagaauaauguagauaagggaagucggcaaaauagauccguaacuucgggauaaggauuggcucuaagggucggguacgaucaacuuagaacugguacggacaaggggaaucugacugucuaauuaaaacauagcauugcgauggucagaaagugauguugacgcaaugugauuucugcccagugcucugaaugucaaagugaagaaauucaaccaagcgcggguaaacggcgggaguaacuaugacucucuuaagguagccaaaugccucgucaucuaauuagugacgcgcaugaauggauuaacgagauucccacugucccuaucuacuaucuagcgaaaccacagccaagggaacgggcuuggcagaaucagcggggaaagaagacccuguugagcuugacucuaguuugacauugugaagagacauaguuucuuuacuuauucaaugaagcggagcuggaauucauuuuccacguucuagcauucaaggucccauucggggcugauccggguugaagacauugucagguggggaguuuggcuggggcggcacaucuguuaaacgauaacgcagauguccuaaggggggcucauggagaacagaaaucuccaguagaacaaaaggguaaaagcccccuugauuuugauuuucagugugaauacaaaccaugaaaguguggccuaucgauccuuuagucccucggaauuugaggcuagaggugccagaaaaguuaccacagggauaacuggcuuguggcagucaagcguucauagcgacauugcuuuuugauucuucgaugucggcucuuccuaucauaccgaagcagaauucgguaagcguuggauuguucacccacuaauagggaacgugagcuggguuuagaccgucgugagacagguuaguuuuacccuacugaugaauguuaccgcaauaguaauugaacuuaguacgagaggaacaguucauucggauaauugguuuuugcggcugucugaucaggcauugccgcgaagcuaccauccgcuggauuauggcugaacgccucuaagucagaauccaugcuagaacgcggugauuucuuugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucgcugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggugcuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuuguauacgacuuagauguacaacgggguauuguaagcaguagaguagccuuguuguuacgaucugcugagauuaagccuuuguugucugauuugu	.........................<<<<<.....<......>......>>>>>...........<<....>>..<<<<<......<<.....>>.....>>>>>..[[[..<<.......<<.<<<<<<...>>>>>>.>>.......>>....<<<<<<<.<<<<<.<<<<<<<<<<<<<<.....<<<<......>>>>.(.......<<<......)>>>....>>>>>>>>..>>>>>>.>....>>>>>>>>>>>........<<<<<<<........>>>>>>>.....(((((..<<<<<<)))))..]]]..................................<<....>>...............<<<<....>>>>..................................<<<<<.<<<<<<.....<<<<<<<.<<<<<<<<<<<<<<<.....<<<<<<<<<......<<<<<......>>>>>.......>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<....>>>.....>>>>>>>....>>>>>>.>>>>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<...<<<<.....>>>>...>>>...<<....>>.......<<<<<..<<<<<....>>>>>...>>>>>.<<<<<<<<...<<....>>...>>>.>>>.>>....>>>>>>.>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<..<<.<<........>>>>.>>>....>>>>>>>>>...<<.......>>......>>>>>>......>.>>..<<<<<<....<.<<<....>>>(><<<<<<<<<<...<<<.<<<<<<<.....<<<....<<<....<<<<...<<<<<.......>>>>>.>>>>....>>>..>.>>.....>>>>>...<<<<.<<<<.........>>>>.>>>>.....>>>>>.>>>>>>>>.>>).<<<<.<<<<<.....>>>>>.>>>>....<<<..[...>>>...<<<<<<<..<<<<(((.....<<<<<<......<.....]....<<<.<<<<<<<<<<.......<<<<<.<<<...<<.........>>...>>>.........<<......>>...>>>>>...>>>>>>>>>>>>>..........))).>....>>>>>>.>>>>..>>>>>>><<<<<<<<<.........>>>>>>>>>....>>>>>><.<<<<<<<..<<......<<<<.<<<<....>>>>>>>>...>>.>>>>>>>..>.....>>>>>><<.....<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<....<<<....>>>........<<<<<<........>>>>>>....>>....>>...<<<<<........>>>>>))<<<<.<<<<<<<.....<<<....>>>.......<<<<<<...<<<<.<<<<<<<.<<<<<<<<<<..{{{..>>>>>><...<<<<<....<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....><<<<<<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>>>>>..........>>>..>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<...............<<<<<...............>>>>><<.<<<<<<<<<<......>>>>..>>>>>>.>>............<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.<..<<<.....<<<<....>>>>.....>>>>>>>>..>>>>><<<<<<.......>>>>>>........<...........<<<<<.......>>>>>.....>.....>>....>>.>>>>>>>.....>>.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>....[[[[[..{{{.{{......[[[[.{{[[[[..<<<<<.<<<<<<<<..<<<<<<<<.......>>>>>>>>...<<<<<.....<<<<..<<............>>...............<<<<<<....>>>>>>..>>>>..>>>>>.....>>>>>>>>..>>>>>...<<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...<<<.<<<<<.......>>>>.>>>>.<<<....>>>.>>))).......((((((..((((.>>>>>>))))))))))..........]]]]..}}]]]].......<<.<...<<<<<<...<<.......>>...>>>>>>....>.>.>.......<<<<<.<<<<<<..<.<<<<<<<......>>>>>>>...>.<<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....}}..}}}.]]]]]....<<<<<<<<..<<<<...<<<<<<...............>>>>>>..<<<<<...<<<<....<<<<<<<<<<}}}.>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>>.......<<<<<<.<<<.<<....<<..........<<<<<<.....>>>>>>......>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>>>>.>>>>>>.............>>.>>>.>>>>>>..<<<<<.<.............>.....<<<<<<<<<.<<<....<<<<....<<<<<......>>>>>...>>>>...>>>....>>>>.>>>>>..>>>>>..	........................(((((......(...[..).......)))).).........((....))...((((......((.]...)).....))))...((((.........(((.((((((...)))))).))....)........((((((.(((((.(.(((..((((((((...({((((......)))))[[(...).(((....}]])))....))))))))....)))..)....)))))))))))...)....(((((((........))))))).....(((((..[[[[[[)))))..)))..................................((....))............(..((((....))))............).....................(((((.((((((.....(((((((((((((((((((((((.......(((((((......((((........)))).......))))))).....))))).))))))))))........(((....)))....))))))))....)))))).))))).[((((........))))((((((....((((((.((((((..(((...(((.......)))...)))...((....)).......(((((..(((((....)))))...))))).((((((((....(....)....))).))).))....)))))).))))))..((.(...((((((.....(((((((((..((((...(((((((....)))))))...)[)))...(((..((.((.......<)))).)))....))))))))).(.((.......))...)..))))))......).))..((((((....(.(((....))).)((((((((((...(((.(((((((.....(((....(((..(.((((...(.((((.....)))).).)))).)..)))..)).).....)))))...((((.((((.(......))))).)))).....))))).)))))))).))..((((.(((((.....))))).))))....(((......)))...(((((((...((([[[...(.((((((......(..........(((.((((((((((.......(((((.(((...((.........))...))).....(...((......)).).)))))...)))))))))))))..........]]].)....))))))))))...)))))))(((((((((.........)))))))))....))))))(.((((((((.((......((((.((((....))))))))...))))))))))..).....))))))((.....((.....((((((.......))))))((((.....((((..((...(((((....((.....))..)))))....[[(((.((...((....(((....)))........(..................)....))....))...(((((........)))))]]((((.((((((((...((((....)))...(.<.((((((...((((.((((((((((((((((((...{{..))))))(...(((((....(((((.....(((.....))).....))))).....)))))....)(((((((......))))))))))).).))))))).))))(...)....))))))...))....))))..)))))))).)))..)).....((......)).)))).((((.....))))..))))..((((.....(((((((.((..(....(.......(((((....(.{..).....)))))((.((((((((((.(...)))))..)))))).))(...).......(((((((((.].((.........))...(((((((....((((.....))))......))))))).}.(((.(((..((((((.(...((.....((((....)))).....)).)))))..)))))(((((.........)))))........((..........(((((.......)))))..)..)....)))....)).))))))).)..))).)))))))..))))))....)).{..(((((.....]}.)))))....(((((..(((.((......((((.((((((..(((((.((((((((..(((((((.........)))))))....((((.....((((..(((..........)))...........>...(((((......)))))..))))..))))......))))))))..)))))..(((......[)).)((((((..........]))))))([((...(((((((.(.((((((.......))))))...).((][.[[[))....)))))))...(((..((((....{..))))..))).(((....))).))]]].].....((((((..((((.]]]]]]))))))))))....)}....))))..)))))).......((.(.(.((((((...((.......))...))))))...)).).)........((((.((((((..(.(((((((......))))))..).).(((.(.....).))).....)))))..)...))).).....(((((((....))).))))..>.))..))).)))))....((((((((..((((.(.(((((......(....).....))))).)(((((...((((....((((((((((}}..)))))..)))))...))))..))))).((((...((((.............))))...)))).))))....)))))))).......((((.(.(((.((....((.(........(((((((..).)))))).....))).......((((((...(((((.(..(((......)))..).))))).)))))).............)).))).).))))..(((((.(..(.......)..)...(.(((((((((.(((....((((.(..(.(..(..)....).)..)))))...)))....)))).)))))).)))))..	Crystal structure of Agelastatin A bound to the 80S ribosome; 25S ribosomal RNA