4www	RA	2854	3.1	RF02541	URS00004B0F34_511145	20855725		0003735		0005840	511145	gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgaugaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguuauaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuaucauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacaucuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcgagcgaacggggagcagcccagagccugaaucaguguguguguuaguggaagcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaugcacaugcugugagcucgaugaguagggcgggacacgugguauccugucugaauauggggggaccauccuccaaggcuaaauacuccugacugaccgauagugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagugaaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggcgugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguagcaagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggcguuaaguugcaggguauagacccgaaacccggugaucuagccaugggcagguugaagguuggguaacacuaacuggaggaccgaaccgacuaauguugaaaaauuagcggaugacuuguggcugggggugaaaggccaaucaaaccgggagauagcugguucuccccgaaagcuauuuagguagcgccucgugaauucaucuccggggguagagcacuguuucggcaagggggucacuuaccaacccgaugcaaacugcgaauaccggagaauguuaucacgggagacacacggcgggugcuaacguccgucgugaagagggaaacaacccagaccgccagcuaaggucccaaagucaugguuaagugggaaacgaugugggaaggcccagacagccaggauguuggcuuagaagcagccaucauuuaaagaaagcguaauagcucacuggucgagucggccugcgcggaagauguaacggggcuaaaccaugcaccgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguucuguaagccugcgaaggugugcugugaggcaugcuggagguaucagaagugcgaaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccggaagaccaaggguuccuguccaacguuaaucggggcagggugagucgaccccuaaggcgaggccgaaaggcguagucgaugggaaacagguuaauauuccuguacuugguguuacugcgaaggggggacggagaaggcuauguuggccgggcgacgguugucccgguuuaagcguguaggcugguuuuccaggcaaauccggaaaaucaaggcugaggcgugaugacgaggcacuacggugcugaagcaacaaaugcccugcuuccaggaaaagccucuaagcaucagguaacaucaaaucguaccccaaaccgacacagguggucagguagagaauaccaaggcgcuugagagaacucgggugaaggaacuaggcaaaauggugccguaacuucgggagaaggcacgcugauauguaggugaggucccucgcggauggagcugaaaucagucgaagauaccagcuggcugcaacuguuuauuaaaaacacagcacugugcaaacacgaaaguggacguauacggugugacgccugcccggugccggaagguuaauugaugggguuagcgcaagcgaagcucuugaucgaagccccgguaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugucggguaaguuccgaccugcacgaauggcguaaugauggccaggcugucuccacccgagacucagugaaauugaacucgcugugaagaugcaguguacccgcggcaagacggaaagaccccgugaaccuuuacuauagcuugacacugaacauugagccuugauggaaguguggacgccagucugcauggcuuuaauguuugauguucuaacguugacccguaauccggguugcggacagugucugguggguaguuugacuggggcggucuccuccuaaagaguaacggaggagcacgaagguuggcuaauccuggucggacaucaggagguuagugcaauggcauaagccagcuugacugcgagcgugacggcgcgagcaggugcgaaagcaggucauagugauccggugguucugaauggaagggccaucgcucaacggauaaaagguacuccggggauaacaggcugauaccgcccaagaguucauaucgacggcgguguuuggcaccucgaugucggcucaucacauccuggggcugaaguaggucccaaggguauggcuguucgccauuuaaagugguacgcgagcuggguuuagaacgucgugagacaguucggucccuaucugccgugggcgcuggagaacugaggggggcugcuccuaguacgagaggaccggaguggacgcaucacugguguucggguugucaugccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaagcaucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaaggguccugaaggaacguugaagacgacgacguugauaggccggguguguaagcgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaaccu	<<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<......<<<<<<....(((.>>>.....<<<<<<<..<<<)))....>>>......>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>>......>>>>>.>.........<<....>>..<<<<<<.....<<.....>>....>>>>>>..(((..<<<<......<<<<<<<<<<<<<.<<<...<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]...............<<....>>....]].........<<<<.....>>>>..................>>>>>>>>>>>.......<<<<..<<<<<......>>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<<<...<<<<<<<<<.....<<<...<<<.<<<<...<<<<<<.>>>>.>>...>>>>.>>>..>>.>.....>>>>>>.>>>...>>>>>>>.>...<<<<<<<<<<......>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<<..<<........<<<<<.<<<..<<<.........>>>..>>>........<<<......>>>..>>>>>....>>..>>>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<..<<....>>..>>>>>....>>>>>>..<<<<<...<<<......<<<<<<<<....>>>>>>>>...>>>..>>>>>........>>>>>>.......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<.<<<...<<<...<<<....>>>...>>>...>>>..<<<<<........>>>>>))<<<<<<<<<<<<<...<<<<....<<<<..<<<..<<<<<<<<<<<....(((...>>>>>><<..<<<<...<<<<<<<<<<<<.<<.....>>>>>>>>>>..>>>>...>>>>...>><..<<<<<....>>>>>...>>>>>>...>>>...>>>>.........>>>>...>>....>>>>>>>>>>>.>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<...............<<<<<...............>>>>><<<<<<.....<<<...<<<<.....>>>>...>>>...>>>>>>............<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<....<...<<<<<..<<....>>...>>>>>..>.....>>>>>>>>..>>>>><<<<<<.......>>>>>>........<...........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>...........<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<<<.<<<<.....<<<<<<<......>>>>>>>....>>>>.>>>>>>>>>>>...<<<.<<<<<<.....>>>>>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>.......<<<<...<<<<<<...<<.......>>...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<))).>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>>>>....>>>.>>>>.......>>>>>>>..<<<<<.....>>>>><....<<..<<<<<.......>>>>>....<<<<<<<<..<<....<<<<<....>>>>>...>>...>>>>>.>>>.....>>..>..>>>>>>>>.	((((((((......((((((((((.....(((..(((((((((((((......((((((.[..[[[.))).....((((((...(((]]]..].))).......))))))...)))....(((....)))(((((((....))))))).(((((((((.........))))))))).))...((((((.....(...[..)......))))).).........((....))...(((((.....((.]...))....)))))...((((.((((......(((((((((((((.(((...(((((......)))))[[(...).(((.....]])))...)))...)))))))))))))...))))...)....((((((((..[......))))))))......(((((].[[[[)))))..)))......)).))))))).))...............((....))....))......(..((((.....))))............)).....)))))))))).....(.((((..(((((......)))))..)))).[.(.(........).).((((((....(((((((((((((..(((...((.....))...)))...((....))..((((.....)))).....)))))))))))))..((.(...((((((.....((((((((((.((((...((((((......))))))...)[)))...(((.(((((.......<))))))))..).))))))))).(.(((.....)))...)..))))))......).))..((((((....(((((....))))).((((((((..((((((((((.....(((...(((.((((...((((((.)))).))...)))).)))..)).).....)))))).)))..)))))))).)...((((((((((......))))))))))....(((......)))...((((.(((...((([[[...(.((((((.....(.....((..(((((..(((.....{.(((((.(((..(((.........)))..))).....(..(((......)))).)))))...)))..))))).))...........]]].)...))))))))))...)))))))(((((((((....)))))))))....))))))(.(((((...(((......((((((((....))))))))...)))..)))))..).....))))))(......((.....((((((.......))))))((((....((((..((..(((((((...((.....)).))))))....[[(((.(((.(.(((...(((....)))...)))..))))..(((((........)))))]]((((((((((.((...((((....((((..(((..((((((((((((...{{{.).))))))((..((((...((((((((((((.((.....))))))))))..))))..[))))...))(..(((((....)))))...))))))...)))...))))(..).....))))...)).....)))))))))).))).))).....((......)).)))).((((.....))))..))))..((((....((((((((.((..(....(.......(((((....(.{..).....)))))((((((.....(((...(((((..)]))))...)))...))))))(...).......(((((((((.].((.........))...(((((((.....(((....))).......))))))).}((((.(((..(((((((..(((........(((((..((....))...)))))........))))))))..)))))(((((.........)))))........((..........(((((.......)))))..)..)....))))...)).))))))).)..))).)))))))).)))))).....)).{..(((((.....]}.)))))..((((((((.(((.((......((((.((((((..(((((.(((.(((((.(((((((((((.((((.....(((((((......)))))))....)))).)))))))))))...(((.((((((.....)))))))))....))))).)))..)))))..(((......[)))((((((..........]))))))([((...(((((((...(((((.........))))).....((][.[[[))....)))))))...((((..((((..{.))))..)))).(((....))).))]]].].....(((((((.((..]]]]..))))))))).....)}......))))..))))))......(((((.(.((((((...((.......))...))))))...)))).).).....(((((.((((((..(((((((((......))))))..))).(((((.....))))).....)))))..)...))).))....(((((((....))).))))..>.))..)))))))))))[...(((((((...((((..(((((((.....(....)....))))))).(((((...((((...(((((((((((}}}.))))))..)))))...)))).)))))...(((....((((.....}.......))))....))).))))..]....)))))))(.(((((.....)))))(....((..(((((.......)))))....((((((((..((....(((((....)))))...))...))))).))).....))..).))))))))).	Crystal structure of the E. coli ribosome bound to CEM-101; 23S rRNA
8e3o	I	2897	1.99	RF02541	URS00004B0F34_562			0003735		0005840	562	gguuaagcgacuaagcguacacgguggaugcccuggcagucagaggcgaugaaggacgugcuaaucugcgauaagcgucgguaaggugauaugaaccguuauaaccggcgauuuccgaauggggaaacccaguguguuucgacacacuaucauuaacugaauccauagguuaaugaggcgaaccgggggaacugaaacaucuaaguaccccgaggaaaagaaaucaaccgagauucccccaguagcggcgagcgaacggggagcagcccagagccugaaucaguguguguguuaguggaagcgucuggaaaggcgcgcgauacagggugacagccccguacacaaaaaugcacaugcugugagcucgaugaguagggcgggacacgugguauccugucugaauauggggggaccauccuccaaggcuaaauacuccugacugaccgauagugaaccaguaccgugagggaaaggcgaaaagaaccccggcgaggggagugaaaaagaaccugaaaccguguacguacaagcagugggagcacgcuuaggcgugugacugcguaccuuuuguauaaugggucagcgacuuauauucuguagcaagguuaaccgaauaggggagccgaagggaaaccgagucuuaacugggcguuaaguugcaggguauagacccgaaacccggugaucuagccaugggcagguugaagguuggguaacacuaacuggaggaccgaaccgacuaaunungaaaaauuagcggaugacuuguggcugggggugaaaggccaaucaaaccgggagauagcugguucuccccgaaagcuauuuagguagcgccucgugaauucaucuccggggguagagcacuguuucggcaagggggucacuuaccaacccgaugcaaacugcgaauaccggagaauguuaucacgggagacacacggcgggugcuaacguccgucgugaagagggaaacaacccagaccgccagcuaaggucccaaagucaugguuaagugggaaacgaugugggaaggcccagacagccaggauguuggcuuagaagcagccaucauuuaaagaaagcguaauagcucacuggucgagucggccugcgcggaagauguaacggggcuaaaccaugcaccgaagcugcggcagcgacgcuuaugcguuguuggguaggggagcguucuguaagccugcgaaggugugcugugaggcaugcuggagguaucagaagugcgaaugcugacauaaguaacgauaaagcgggugaaaagcccgcucgccggaagaccaaggguuccuguccaacguuaaucggggcagggugagucgaccccuaaggcgaggccgaaaggcguagucgaugggaaacagguuaauauuccuguacuugguguuacugcgaaggggggacggagaaggcuauguuggccgggcgacgguugucccgguuuaagcguguaggcugguuuuccaggcaaauccggaaaaucaaggcugaggcgugaugacgaggcacuacggugcugaagcaacaaaugcccugcuuccaggaaaagccucuaagcaucagguaacaucaaaucguaccccaaaccgacacngguggucagguagagaauaccaaggcgcuugagagaacucgggugaaggaacuaggcaaaauggugccguaacuucgggagaaggcacgcugauauguaggugaggucccucgcggauggagcugaaaucagucgaagauaccagcuggcugcaacuguuuauuaaaaacacagcacugugcaaacacgaaaguggacguauacggugugacgccuncccggugccggaagguuaauugaugggguuagcgcaagcgaagcucuugaucgaagccccgguaaacggcggccguaacnauaacgguccuaagguagcgaaanuccuugucggguaaguuccgacnugcacgaauggcguaaugauggccaggcugucuccacccgagacucagugaaauugaacucgcugugagaugcaguguacccgcggcaagacggaaagaccccgunaaccuuuacuauagcuugacacugaacauugagccuugauguguaggauaggugggaggcuuugaaguguggacgccagucugcauggagccgaccuugaaauaccacccuuuaauguuugauguucuaacguugacccguaauccggguugcggacagugucugguggguaguuugacugnggcggucuccuccuaaagaguaacggaggagcacgaagguuggcuaauccuggucggacaucaggagguuagugcaauggcauaagccagcuugacugcgagcgugacggcgcgagcaggugcgaaagcaggucauagugauccggugguucugaauggaagggccaucgcucaacggauaaaagguacuccgnggauaacaggcugauaccgcccaagaguucauaucgacggcgguguuuggcancucgnugucggcucaucacauccuggggcugaaguaggucccaaggguauggcnguucgccauuuaaagugguacgcgagcuggguuuagaacgucgugagacaguucggucccuaucugccgugggcgcuggagaacugaggggggcugcuccuaguacgagaggaccggaguggacgcaucacugguguucggguugucaugccaauggcacugcccgguagcuaaaugcggaagagauaagugcugaaagcaucuaagcacgaaacuugccccgagaugaguucucccugacccuuuaaggguccugaaggaacguugaagacgacgacguugauaggccggguguguaagcgcagcgaugcguugagcuaaccgguacuaaugaaccgugaggcuuaaccuu	<<<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<......<<<<<<.[..(((.>>>.....<<<<<<<..<<<)))..].>>>......>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<<<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>>......>>>>>.>.........<<....>>..<<<<<<.....<<.....>>....>>>>>>..(((..<<<<......<<<<<<<<<<<<<.<<<...<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>>>>>>>>>>...>>>>........<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]...............<<....>>....]].........<<<<.....>>>>..................>>>>>>>>>>>.......<<<<..<<<<<......>>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<<<...<<<<<<<<<.....<<<...<<<.<<<<...<.<.........>>...>>>>.>>>..>>.>.....>>>>>>.>>>...>>>>>>>.>...<<<<<<<<<<......>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<<..<<........<<<<<.<.....<<.........>>.....>........<<<......>>>..>>>>>....>>..>>>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<<<<......>>>>>>>>....>>>>>><.<<<<<...<<<......<<<<<<<<....>>>>>>>>...>>>..>>>>>..>.....>>>>>><......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<.<<<...<<<...<<<....>>>...>>>...>>>..<<<<<........>>>>>))<<<<<<<<<<<<<...<<<<....<<<<..<<<..<<<<<<<<<<<....(((...>>>>>><<..<<<<...<<<<<<<<<<<<.<<.....>>>>>>>>>>..>>>>...>>>>...>><..<<<<<....>>>>>...>>>>>>...>>>...>>>>.........>>>>...>>....>>>>>>>>>>>.>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<...............<<<<<.....<..>......>>>>><<<<<<.....<<<...<<<<.....>>>>...>>>...>>>>>>............<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<....<...<<<<<..<<....>>...>>>>>..>.....>>>>>>>>..>>>>><<<<<.........>>>>>........<...........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<.......>>>>>..<<<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<.<<<<<.<<<<<<<<.<<.................<<<<.................................................>>>>........>>.>>>>>>>>...<<<.<<<<<<.....>>>>>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<...(((>>....>>>>>>>...<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>.......<<<<...<<<<<<...<<.......>>...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<))).>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>>>>....>>>.>>>>.......>>>>>>>..<<<<<.....>>>>><....<<..<<<<<.......>>>>>....<<<<<<<<..<<....<<<<<....>>>>>...>>...>>>>>.>>>.....>>..>..>>>>>>>>..	((((((((......((((((((((.....(((..(((((((((((((......((((((.[..[[[.))).....((((((...(((]]]..].))).......))))))...)))....(((....)))(((((((....))))))).(((((((((.........))))))))).))...((((((.....(...[..)......))))).).........((....))...(((((.....((.]...))....)))))...((((.((((......(((((((((((((.(((...(((((......)))))[[(...).(((.....]])))...)))...)))))))))))))...))))...)....((((((((..[......))))))))......(((((].[[[[)))))..)))......)).))))))).))...............((....))....))......(..((((.....))))............)).....)))))))))).....(.((((..(((((......)))))..)))).[.(.(........).).((((((....(((((((((((((..(((...((.....))...)))...((....))..((((.....)))).....)))))))))))))..((.(...((((((.....((((((((((.((((...((((.(......).))))...)[)))...(((.(((((........))))))))..).))))))))).(.(((.....)))...)..))))))......).))..((((((....(((((....))))).((((((((..((((((((((.....(((...(((.((((...(............)...)))).)))..)).).....)))))).)))..)))))))).)...(((((((((........)))))))))....(((......)))...((((.(((...((([[[...(.((((((.....(.....((..(((((..(((.....{.((((.(......((.........))...............(........)...)))))...)))..))))).))...........]]].)...))))))))))...)))))))((((((.(......).))))))....))))))(.(((((...(((......((((((((....))))))))...)))..)))))..).....))))))(......((.....((((((.......))))))((((....((((..((..(((((((...((.....)).))))))....[[(((.(((.(.(((...(((....)))...)))..))))..(((((........)))))]](((((((((((((...((((....((((..(((..((((((((((((...{{{.).))))))((..((((....(((((((((((.((.....))))))))))..)))...[))))...))(..(((((....)))))...))))))...)))...))))(..).....))))...))....))))))))))).))).))).....((......)).)))).((((.....))))..))))..((((....((((((((.((..(....(.......(((((....(.{..).....)))))((((((.....(((...((((....]))))...)))...))))))(...).......(((((((((.].((.........))...(((((((.....(((....))).......))))))).}((((.(((..(((((((..(((........(((((..((....))...)))))........))))))))..)))))((((...........))))........((.(......).(((((.......)))))..)..)....))))...)).))))))).)..))).)))))))).)))))).....)).{..(((((....]}.)))))..((((((((.(((.((......((((.((((((..(((((.(((.(((((.(((((((((.....(..(..........(.......(.......................(..)..).................).)..).....)))))))))...(((.((((((.....)))))))))....))))).)))..)))))..(((......[)))((((((..........]))))))([((...(((((((...(((((.........))))).....((][.[[[))....)))))))...((((..((((..{.))))..)))).(((....))).))]]].].....(((((((.((..]]]]..))))))))).....)}......))))..))))))......((((..(.((((((...((.......))...))))))...).)).).)......(.((.((((((..(((((((((......))))))..))).(((((.....))))).....)))))..)...))..).....(.(((((....))).)).)....))..)))))))))))[...(((((((...((((..(((((((.....(....)....))))))).(((((...((((...(((((((((((}}}.))))))..)))))...)))).)))))...(((....((((.....}.......))))....))).))))..]....)))))))(.(((((.....)))))(....((..(((((.......)))))....((((((((..((....(((((....)))))...))...))))).))).....))..).)))))))))..	E. coli 50S ribosome bound to solithromycin and VM1; 23S ribosomal RNA
9qeg	A	2586	2.21	RF02541		40490363		0003735		0005840	367830	uuaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgaugaaggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuugauccagagauuuccgaauggggaaacccagcaugaguuaugucauguuaucgauaugugaauacauagcauaucagaaggcacacccggagaacugaaacaucuuaguacccggaggaagagaaagaaaaucgauucccuuaguagcggcgagcgaaacgggaagagcccaaaccaacguugggguugaggacagaguuacaaaggacgacauuagacgaaucaucuggaaagaugaaucaaagaagguaauaauccuguagucgaaaauguugucucucuuauccugaguacgacggagcacgugaaauuccgucggaaucugggaggaccaucuccuaaggcuaaauacucucuagugaccgauagugaaccaguaccgugagggaaaggugaaaagcaccccggaaggggagugaaauagaaccugaaaccgugugcuuacaaguagucagagcccguuaaugggugauggcgugccuuuuguagaaugaaccggcgaguuacgauuugaugcaagguuaagcaguaaauguggagccguagcgaaagcgagucugaauagggcguuuaguauuuggucguagacccgaaaccaggugaucuacccuuggucagguugaaguucagguaacacugaauggaggaccgaaccgacuuacgungaaaagugagcggaugaacugaggguagcggagaaauuccaaucgaaccuggagauagcugguucucuccgaaauagcuuuagggcuagccucaagugaugauuauuggagguagagcacuguuuggacgauucagacaaacuccgaaugccaauaauuuaacuugggagucagaacaugggugauaagguccguguucgaaagggaaacagcccagaccaccagcuaaggucccaaaauauauguuaaguggaaaaggauguggcguugccgugacacugcgccgaaaauguaccggggcuaaacauauuaccgaagcuguggauuguccggacaaugguaggagagcguucuaagggcguugaagcaugaucguaaggacauguggagcgcuuagaagugagaaugccggugugaguagcgaaagacgggugagaaucccguccaccgauugacuaagguuuccagaggaaggcucguccgcucuggguuagucggguccuaagcugaggccgacaggcguaggcgauggauaacagguugauauuccuguaccaccuauauggggggacgcaguaggauaggcgaagcgugcgauuggaugcacgucuaagcaguaaggcugcugagcugugauggggagaauucgagucguugauuucacacugccgagaaaagccucuauaggugcccguaccgcaaaccgacacagguagucaagaugagaauucuaaggugagcgagcgaacucucguuaaggaacucggcaaaaugaccccguaacuucgggagaaggggugcucuuagagccgcagugaauaggcccaagcgacuguuuaucaaaaacacaggucucugcuaaaccguaaggugauguauaggggcugacgccugcccggugcuggaagguuaagaggagugguugaagcuacgaaucgaagccccaguaaacggcgguccuaagguagcgaaanuccuugucggguaaguuccgacccgcacgaaaggcguaacgauuugggcacugucucaacgagagacucggugaaaucauaguaccugugaagaugcagguuacccgcgacaggacggaaagaccccguggagcuuuacuguagccugauauugaaauuuucuaacccgcaccacuuaucguggugggagacagugucaggcgggcaguuugacugnggcggucgccuccuaaaagguaacggaggcgcucaaagguucccucagaaugguucauucauagaguguaaaggcauaagggagcuugacugcgagaccuacaagucgagcagggucgaaagacggacuuagugauccggugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccgngganaacaggcuuaucucccccaagaguucacaucgacggggagguuuggcaccucgnugucggcucaucgcauccuggggcuguagucggucccaaggguugggcuguucgcccauuaaagcgguacncgagcuggguucagaacgucgugagacaguucggucccuauccgucgugggcguaggaaauuugagaggagcuguccuuaguacgagaggaccgggauggacauaccucugguguaccaguugucgugccaacggcauagcuggguagcuauguguggacgggauaagugcugaaagcaucuaagcaugaagccccccucaagaugagauuucccaacguuauaagaucccucaaagaugaugagguuaauagguucgagguggaagcauggugacauguggagcugacgaauacuaaucgaucgaagacuuaau	<<<<<<......<<<<<<<<<<<.....[[.(((<<<<<<<[[.<......<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<<<<<<<<.........>>>>>>>.>>.>.....<<<<<......<<....>>.......>>>>.>.........<<...>>..<<<<<......<<.....>>.....>>>>>..(((....<<<<..>>>>.....<<<<..<<<.......<<<<<<<<<<.<<<...<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>>>>>>>>>>...>>>>.....<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..)))......]].>>>>>>>.)))..............<<....>>....]].........<<<<....>>>>..................>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<.<<<<<..<<<...<<<.....>>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<<<<<<.....<<<...<<<<<<<<...>>>>>>>>..>>.>.....>>>>>>>>>..>>>>>>>.>>..<<<<<<<<<<......>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<.<<<<<.>>>>>.>>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<<<>>>>>>>....>>>>>>..<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>........>>>>>><......<<....<<<<<<.......>>>>>><<<<....<<<<<.<<<..<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<..<<<<....<<<<..<<<..<<<<<.<<<<<<...(((..>>>>>><<..<<<<<..<<<.>>>..>>>>>...>>...<<..>>...>>>>>...>>>...>>>>.........>>>>.>>>>>>>>>>>.>>>.....<<......>>>>>>>.<<<<....>.>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<...............>>>>><<<<<.>>>>>............<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<..<<...<<<<<....>>>>>...>>..>>>>>>>>>..>>>>><..>........<...........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<.>>>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>>>>....>>>.>>>>.......>>>>>>>.<<..>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>>>>.	((((((......((((((((((.....(((..(((((((((((.(......((((((.[[..[[[)))...].((((((...(((]]..]].)))......))))))...)))....(((....)))((((((........)))))).(((((((((.........))))))).)).).....(((((......(...[..).......)))).).........((...))...((((......((.]...)).....))))...((((...((((()))))....[((((..(((.......((((((((((.(((...(((((......)))))[[(...).(((.....]])))...)))...)))))))))))))...)))))....(((((((...{.......)))))))....].(((((}.[[[[)))))..)))......)).))))))).))...............((....))....))......(..((((....))))............)).....)))))))))).....(.((((..((((..[...))))..)))).<.(.(........).).((((((..(.(((((((.(((((..(((...(((.....)))...)))...((....))..((((.....)))).....))))).)))))))..((.(...((((((.....((((((((((.((((...((((((......))))))...)<)))...(((.(((((.......A))))))))..).))))))))).(.(((....[)))...).]))))))......).))).((((((....(((((....)))))(((((((((..((((((((((.....(((...((((((((...))))))))..)).).....))))))))).)))))))).))..((((((((((......))))))))))....(((......)))...((((.(((...((([[[...(.((((((.....(.....((..((((.(((((.))))).)))).))...........]]].)...))))))))))...)))))))((((((()))))))....))))))(.(((((((.((......(((((.((....))])))))...)).)))))))..).....))))))(......((....((((((.......))))))((((....((((..((..(((((((...((.....)).))))))....[[((((.((.(.(((...(((....)))...)))..)))...(((((........)))))]](((((((..((((....(((((.(((..(((((.((((((....{{..))))))((..(((((..(((.)))..)))))...))...((()))...)))))...)))..)))))(..).....)))).))))))))))).))).....((......)).)))).(((.......)))..))))..((((....((((((((.((..(....(.......(((((....(.[..).....)))))(((((.)))))(...).......(((((((((.>.((.........))...(((((((.....(((....))).......))))))).]((((.(((..(((((((..(((...((...(((((....)))))...))...))))))))..)))))(..)........((..........(((((.......)))))..)..)....))))...)).))))))).)..))).)))))))).)))))).....)).[..(((((.....>].)))))..((((((((.(((.((......((((.((((((..(((((.(((((((((.((((.))))....((.((((((.....)))))))).....)))))))))..)))))..(((......[)))((((((..........]))))))([((...(((((((.(.(((((...)))))...).((][.[[[))....)))))))...((((..(((...{..)))..)))).(((....))).))]]].].....(((((((.((..]]]]..))))))))).....)}......))))..))))))......((((..(.((((((...((.......))...))))))...).)).).)......(.((.((((((..(((((((((......))))))..))).(((((.....))))).....)))))..)...))..).....(.(((((....))).)).)..a.))..)))))))))))[...(((((((...((((..(((((((.....(....)....))))))).(((((...((((...(((((((((((.}}.))))))..)))))...)))).)))))...(((....((((.............))))....))).))))..]....)))))))(((()))....(((((((((.......)))))....((((((((.(((....(((((....)))))...)))..))))).)))...))))...))))))).	Cryo-EM structure of the 70S ribosome of a MLSb sensitive S. aureus strain ""KES34"" in complex with solithromycin; 23S ribosomal RNA
9qeh	A	2616	2.08	RF02541		40490363		0003735		0005840	367830	uuaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgaugaaggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuugauccagagauuuccgaauggggaaacccagcaugaguuaugucauguuaucgauaugugaauacauagcauaucagaaggcacacccggagaacugaaacaucuuaguacccggaggaagagaaagaaaaucgauucccuuaguagcggcgagcgaaacgggaagagcccaaaccaacguugggguugaggacaggaguuacaaaggacgacauuagacgaaucaucuggaaagaugaaucaaagaagguaauaauccuguagucgaaaauguugucucucuuauccugaguacgacggagcacgugaaauuccgucggaaucugggaggaccaucuccuaaggcuaaauacucucuagugaccgauagugaaccaguaccgugagggaaaggugaaaagcaccccggaaggggagugaaauagaaccugaaaccgugugcuuacaaguagucagagcccguuaaugggugauggcgugccuuuuguagaaugaaccggcgaguuacgauuugaugcaagguuaagcaguaaauguggagccguagcgaaagcgagucugaauagggcguuuaguauuuggucguagacccgaaaccaggugaucuacccuuggucagguugaaguucagguaacacugaauggaggaccgaaccgacuuacgungaaaagugagcggaugaacugaggguagcggagaaauuccaaucgaaccuggagauagcugguucucuccgaaauagcuuuagggcuagccucaagugaugauuauuggagguagagcacuguuuggacgauucagacaaacuccgaaugccaauaauuuaacuugggagucagaacaugggugauaagguccguguucgaaagggaaacagcccagaccaccagcuaaggucccaaaauauauguuaaguggaaaaggauguggcguugccgugacacugcgccgaaaauguaccggggcuaaacauauuaccgaagcuguggauuguccggacaaugguaggagagcguucuaagggcguugaagcaugaucguaaggacauguggagcgcuuagaagugagaaugccggugugaguagcgaaagacgggugagaaucccguccaccgauugacuaagguuuccagaggaaggcucguccgcucuggguuagucggguccuaagcugaggccgacaggcguaggcgauggauaacagguugauauuccuguaccaccuauaucgauggggggacgcaguaggauaggcgaagcgugcgauuggaugcacgucuaagcaguaaggcuuauuggcaaauccgguagcugagcugugauggggagaauucgagucguugauuucacacugccgagaaaagccucuagaaauaggugcccguaccgcaaaccgacacagguagucaagaugagaauucuaaggugagcgagcgaacucucguuaaggaacucggcaaaaugaccccguaacuucgggagaaggggugcucuuagagccgcagugaauaggcccaagcgacuguuuaucaaaaacacaggucucugcuaaaccguaaggugauguauaggggcugacgccugcccggugcuggaagguuaagaggagugguugaagcuacgaaucgaagccccaguaaacggcggccuaagguagcgaaanuccuugucggguaaguuccgacccgcacgaaaggcguaacgauuugggcacugucucaacgagagacucggugaaaucauaguaccugugaagaugcagguuacccgcgacaggacggnaagaccccguggagcuuuacuguagccugauauugaaauucggcuuucuaacccgcaccacuuaucguggugggagacagugucaggcgggcaguuugacugnggcggucgccuccuaaaagguaacggaggcgcucaaagguucccucagaaugguucauucauagaguguaaaggcauaagggagcuugacugcgagaccuacaagucgagcagggucgaaagacggacuuagugauccggugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccgngganaacaggcuuaucucccccaagaguucacaucgacggggagguuuggcaccucgnugucggcucaucgcauccuggggcuguagucggucccaaggguugggcuguucgcccauuaaagcgguacncgagcuggguucagaacgucgugagacaguucggucccuauccgucgugggcguaggaaauuugagaggagcuguccuuaguacgagaggaccgggauggacauaccucugguguaccaguugucgugccaacggcauagcuggguagcuauguguggacgggauaagugcugaaagcaucuaagcaugaagccccccucaagaugagauuucccaacguuauaagaucccucaaagaugaugagguuaauagguucgagguggaagcauggugacauguggagcugacgaauacuaaucgaucgaagacuuaau	<<<<<<......<<<<<<<<<<<.....[[.(((<<<<<<<[[.<......<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<<<<<<<<.........>>>>>>>.>>.>.....<<<<<......<<....>>.......>>>>.>.........<<...>>..<<<<<......<<.....>>.....>>>>>..(((....<<<<..>>>>.....<<<<..<<<<.......<<<<<<<<<<.<<<...<<<<<......>>>>>((......<<<.....))>>>...>>>...>>>>>>>>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..)))......]].>>>>>>>.)))..............<<....>>....]].........<<<<....>>>>..................>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>>...<.<........>.>.<<<<<<....<<<<<<<.<<<<<..<<<...<<<.....>>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<<<<<<.....<<<...<<<<<<<<...>>>>>>>>..>>.>.....>>>>>>>>>..>>>>>>>.>>..<<<<<<<<<<......>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<.<<<<<.>>>>>.>>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<<..>>>>>>....>>>>>>..<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>........>>>>>><......<<....<<<<<<.......>>>>>><<<<....<<<<<.<<<..<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<.<<...<<<<....<<<<..<<<..<<<<<.<<<<<<...(((..>>>>>><<..<<<<<..<<<.<<<<<<.....>>>>>>>>>..>>>>>...>>...<<..>>...>>>>>...>>>...>>>>.........>>>>..>>.>>>>>>>>>>>.>>>.....<<......>>>>>>>.<<<<....>.>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<...............>>>>><<<<<.>>>>>............<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<..<<...<<<<<....>>>>>...>>..>>>>>>>>>..>>>>>...........<...........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<.<..>.>>>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>>>>....>>>.>>>>.......>>>>>>>.<<..>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>>>>.	((((((......((((((((((.....(((..(((((((((((.(......((((((.[[..[[[)))...].((((((...(((]]..]].)))......))))))...)))....(((....)))(((((((......))))))).(((((((((.........))))))).)).).....(((((......(...[..).......)))).).........((...))...((((......((.]...)).....))))...((((...((((()))))....[((((..((((........(((((((((.(((...(((((......)))))[[(...).(((.....]])))...)))...))))))))).))))..)))))....(((((((...{.......)))))))....].(((((}.[[[[)))))..)))......)).))))))).))...............((....))....))......(..((((....))))............)).....)))))))))).....(.((((..((((..[...))))..)))).<.(.(........).).((((((....(((((((.(((((..(((...(((.....)))...)))...((....))..((((.....)))).....))))).)))))))..((.(...((((((.....((((((((((.((((...((((((......))))))...)<)))...(((.(((((.......A))))))))..).))))))))).(.(((....[)))...).]))))))......).))..((((((....(((((....)))))(((((((((..((((((((((.....(((...((((((((...))))))))..)).).....))))))))).)))))))).))..((((((((((......))))))))))....(((......)))...((((.(((...((([[[...(.((((((.....(.....((..((((.(((((.))))).)))).))...........]]].)...))))))))))...)))))))((((((()))))))....))))))(.(((((((.((......(((((.((....))])))))...)).)))))))..).....))))))(......((....((((((.......))))))((((....((((..((..(((((((...((.....)).))))))....[[((((.((.(.(((...(((....)))...)))..)))...(((((........)))))]](((((((.((...((((....(((((.(((..(((((.((((((....{{..))))))((..(((((..(((.((((((.....)))))))))..)))))...))...((()))...)))))...)))..)))))(..).....))))..)).))))))))))).))).....((......)).)))).(((.......)))..))))..((((....((((((((.((..(....(.......(((((....(.[..).....)))))(((((.)))))(...).......(((((((((.>.((.........))...(((((((.....(((....))).......))))))).]((((.(((..(((((((..(((...((...(((((....)))))...))...))))))))..)))))(.)........((..........(((((.......)))))..)..)....))))...)).))))))).)..))).)))))))).)))))).....)).[..(((((.....>].)))))..((((((((.(((.((......((((.((((((..(((((.(((((((((.((((.(()).))))....((.((((((.....)))))))).....)))))))))..)))))..(((......[)))((((((..........]))))))([((...(((((((.(.(((((...)))))...).((][.[[[))....)))))))...((((..(((...{..)))..)))).(((....))).))]]].].....(((((((.((..]]]]..))))))))).....)}......))))..))))))......((((..(.((((((...((.......))...))))))...).)).).).....((.((.((((((..(((((((((......))))))..))).(((((.....))))).....)))))..)...))..))....(.(((((....))).)).)..a.))..)))))))))))[...(((((((...((((..(((((((.....(....)....))))))).(((((...((((...(((((((((((.}}.))))))..)))))...)))).)))))...(((....((((.............))))....))).))))..]....)))))))(((()))....(((((((((.......)))))....((((((((.(((....(((((....)))))...)))..))))).)))...))))...))))))).	Cryo-EM structure of the A2085-methylated 50S ribosome of a MLSb resistant S. aureus strain ""MNY196"" in complex with solithromycin; 23S rRNA