3jq4	A	2765	3.52	RF02540,RF02541	URS000080DEF1_243230	20080686		0003735		0005840	243230	ggucaagauaguaaggguccacgguggaugcccuggcgcuggagccgaugaaggacgcgauuaccugcgaaaagccccgacgagcuggagauacgcuuugacucggggauguccgaauggggaaacccaccucguaagagguauccgcaaggaugggaacucagggaacugaaacaucucaguaccugaaggagaagaaagagaauucgauuccguuaguagcggcgagcgaacccggaucagcccaaauucaaccccucaagccgaaguggcuggaaagcuacaccucagaaggugagaguccuguaggcgaacgagcgguugacuguaaggucguuguucgugaaacgaugacugaauccgcgcggaccaccgcgcaaggcuaaauacucccagugaccgauagcgcauaguaccgugagggaaaggugaaaagaaccccgggaggggagugaaagagaaccugaaaccguggacuuacaagcagucauggcaccuuaugcguguuauggcgugccuauugaagcaugagccggcgacuuagaccugacgugcgagcuuaaguugaaaaacggaggcggagcgaaagcgaguccgaauagggcggcauuaguacgucgggcuagacucgaaaccaggugagcuaagcaugaccagguugaaacccccgugacagggggcggaggaccgaaccggugccugcugaaacagucucggaugaguuguguuuagagugaaaagcuaaccgaaccuggagauagcuaguucuccccgaaauguauugagguacagccucggauguugaccauguccuguagagcacucacaaggcuaaaaccuuaugaaacuccgaaggggcacgcguuuaguccgggagugaggcugcgagagcuaacuuccguagccgagagggaaacaacccagaccaucagcuaaggucccuaaaugaucgcucagugguuaaggaugugucgucgcauagacagccaggagguuggcuuagaagcagccacccuucaaagagugcguaauagcucacuggucgagugacgaugcgccgaaaaugaucggggcucaagugaucuaccgaagcuauggauucaacucgcgaagcgaguugucugguaggggagcguucaguccgcggagaagccauaccggaaggagugguggagccgacugaagugcggaugccggcaugaguaacgauaaaagaagugagaaucuucuucgccguaaggacaaggguuccuggggaagggucguccgcccagggaaagucgggaccuaaggugaggccgaacggcgcagccgauggacagcaggucaagauuccugcaccgaucauguggagugauggagggacgcauuacgcuauccaaugccaagcuauggcuaugcugguugguacgcucaagggcgaucgggucagaaaaucuaccggucacaugccucagacguaucgggagcuuccucggaagcgaaguuggaaacgcgacggugccaagaaaagcuucuaaacguugaaacaugauugcccguaccgcaaaccgacacagguguccgagugucaaugcacuaaggcgcgcgagagaacccucguuaaggaacuuugcaaucucaccccguaacuucggaagaagggguccccacgcuucgcguggggcgcagugaauaggcccaggcgacuguuuaccaaaaucacagcacucugccaacacgaacaguggacguauagggugugacgccugcccggugccggaaggucaaguggagcggugcaagcugcgaaaugaagccccggugaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugucggguaaguuccgaccugcacgaaaggcguaacgaucugggcgcugucucaacgagggacucggugaaauugaauuggcuguaaagaugcggccuacccguagcaggacgaaaagaccccguggagcuuuacuauagucuggcauugggauucggguuucucugcguaggugggagaaacuggccggucgguggccacccugagaaacuuggauuucuaaccugaaaaaucacuuucggggaccgugcuuggcggguaguuugacuggggcggucgccucccaaaauguaacggaggcgcccaaaggucaccucaagacgguuggaaaucgucuguagagcgcaaagguagaagguggcuugacugcgagacugacacgucgagcagggaggaaacucgggcuuagugaaccggugguaccguguggaagggccaucgaucaacggauaaaaguuaccccggggauaacaggcugaucucccccgagaguccauaucggcggggagguuuggcaccucgaugucggcucgucgcauccuggggcugaagaaggucccaaggguugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgugagacaguucggucucuauccgcuacgggcgcaggagaauugaggggaguugcuccuaguacgagaggaccggagugaacggaccgcuggucucccugcugucguaccaacggcacaugcaggguagcuauguccggaacggauaaccgcugaaagcaucuaagcgggaagccagccccaagaugaguucucccacuguucagguaagacucccggaagaccaccggguuaagaggccaggcgugcacgcauagcaauguguucagcggacuggugcucaucagucgaggucuugacca	<<<<<<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<<<<<<....((>>>>.....<<<<<<...<<.))......>>......>>>>>>...>>>....<<<....>>><<<<<....>>>>><<<<....>>>>>>...<<<<<<.....<<....>>......>>>>>.>.........<<....>>...<<<<......<<.....>>.....>>>>...<<<...<.<<<<<<..<<..<<<...<<<<<......>>>>>((......<<<.....))>>>...>>>....>>..>>>>>>.>....<<<<<<<<.........>>>>>>>>......<<<<<..((((>>>>>..>>>......>>.>>>>>>.>>..............<<....>>....>>.........<<<<....>>>>..................>>>>>>>>>>>.......<<<<<<<<<<.......>>>>>>>>>>...<.<........>.>.<<<<<<....<<<.<<<<<<<<<....<.....<.....>.....>.....<<....>>...<<......>>..........>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<.....<<<<<......>>>>>......>>>...<<<<.<.<<<......>>>.>>>>>....>>>>>>>>>..<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<.<<<<<<...<<<...<<<.<<<<......>>>>.>>>..>>.>...>>>>>>.>.>>>..>>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<<<<<.<.......<<<<<.<<<...................>>>.........<<......>>...>>>>>...>.>>>>>>>>.>>..........)))......>>>>>>.>>>...>>>>>>>..<..<<<<.......>>>>.>.......>>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<<..>>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<<<...<<....<<<....<<<<..<<<..<<<<<.<<<<.<<...[[....>>>>>>.<....<.<..<<<..<<<<<<.............>>>>>>.....>>>..>.>...>.......<<.....>.>......>>>>>...>>>...>>>>.........>>>....>>......>>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<<....>>>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<...............>>>>><<<<<<<<...>>>>>>>>............<<<<<<<<<..<<...........>>..<<<<<<<.....<<<.....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<...<....<<<<<....>>>>>....>...>>>>>>>>..>>>>>.<<<<<.......>>>>>.........<...........<<<<<.......>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.<<<.........<<<<.<<<<<<..<<<<<.<<<.<<<<<.<<<<<<...<<.<<<<......<.<.......<<.<.<..>>..>>....>.>..>>>>.>>...>>>>>>...<<<.<<.......>>..>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<....(((.>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.<<..))))..>>>>>>>>>.............>>>>..>>>>>>.......<<<<...<<<<<<...<<.......>>...>>>>>>....>>>.>.......<<<<<..<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>......>>>.>>....<<<<<<<....>>>.>>>>........>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.]].>>>>>>...>>>>>...>>>>.>>>>>....<<....<<<<<...........>>>>>....>>..>>>>.......>>>>>>>..............<<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>>>>>>.	((((((((......((((((((((.....(((..(((.((((((((......((((((.[[..[[.))).....((((((...((.]]..]]..))......))))))...)))....(((....)))(((((....))))).(((....))).))...((((((.....(...[..)......))))).).........((....))...((((......((.]...)).....))))...(((.....((((((..((..(((...(((((......)))))[[(...).(((.....]])))...)))....))..))))))......(((((((((.......)))))))))......(((((..[[[[)))))..)))......)).)))).).))..............((....))....))......(..((((....))))............)).....)))))))))).......((((((((((.......)))))))))).[.(.(........).).((((((....(((.((((((((((...(.....(.....).....).....((....))....(......)..........)))))))))))))..((.(...((((((.....(((((((((..((((....(((((......)))))....)[)))...((...(.(((......))).)..))....)))))))))..(((.....)))......))))))......).))..((((((....(((((....)))))(((((((((..(.(((.(((((....(((...(((.((((......)))).)))..)).)....))))).).))..)))))))).))..(((((((.((......)).)))))))....(((......)))...((((.(((...((([[[...(.(((((((....(.....((..((.(((((.(.......(((((.(((..(.(.........).)..))).....(...((......)).).)))).)..).))))).)).))..........]]].)..).))))))))))...)))))))....(((.(((...))).)))........))))))(.(((((((.((.......((((.((....)).))))....)).)))))))..).....))))))(......((.....((((((.......))))))((((....((((..((...((((((...((.....)).))))))....[[((((.((.(.(((...(((....)))...)))..)))...(((((........)))))]](.(((((((...((....(((....(((((.(((..(((((..(((.((...{{....)))))....(.(......((..((((((....(.....)..)))))).....))......).)......(.(((....))).)....)))))...)))..)))))(..).....)))....))......))))))).)))))..)).....((......)).)))).((((......))))..))))..((((....((((((((.((..(....(.......(((((....(....).....)))))((((((((...))))))))(...).......(((((((((.].(...........)...(((((((.....(((.....))).......)))))))..((((.(((..(((((((..(((....(...((.((....)).))...)....))))))))..)))))(.((((.......)))).)........((..........(((((.......)))))..)..)....))))...)).))))))).)..))).)))))))).)))))).....)..{..(((((.....]}.)))))..((((((((.(((..(......((((.((((((..(((((.(.(.(((((.(.(((.(..(..((((.(....((((......((...(())...))...))))).))))..)..).))).)...((.((((......)))).))....))))).).)..)))))..(((......[)))((((((..........]))))))([((...(((((((.(.(((((.........)))))...).((][.[[[))....)))))))...((((..(((...{..)))..)))).(((....))).))]]].].....((((((..((..]]]]..)).)))))).....)}......))))..))))))......(((((.(.((((((...((.......))...))))))...)))).).)......((((.((((((..(((((((((......))))))..))).(((((.....))))).....)))))..)...))).).....(((((((....))).))))....)...)))))))))))[...(((((((...((((..(((((((...............))))))).(((((...(((....(((((((((((.}}.))))))...)))))....))).)))))....((....((((.............))))....))..))))..]....)))))))..(.(..).)....(((((((((.......)))))....((((((((.(((....(((((....)))))...)))..))))).)))...))))....)))))))).	The structure of the complex of the large ribosomal subunit from D. Radiodurans with the antibiotic lankacidin; 23S ribosomal RNA
3pip	X	2644	3.45	RF02540,RF02541	URS000080DEF1_243230	21282615		0003735		0005840	243230	ggucaagauaguaaggguccacgguggaugcccuggcgcuggagccgaugaaggacgcgauuaccugcgaaaagccccgacgagcuggagauacgcuuugacucggggauguccgaauggggaaacccaccucguaagagguauccgcaaggaugggaacucagggaacugaaacaucucaguaccugaaggagaagaaagagaauucgauuccguuaguagcggcgagcgaacccggaucagcccaaucaagccgaaguggcuggaaagcuacaccucagaaggugagaguccuguaggcgaacgagaggucguuguucgugaaacgaugacugaauccgcgcggaccaccgcgcaaggcuaaauacucccagugaccgauagcgcauaguaccgugagggaaaggugaaaagaaccccgggaggggagugaaagagaaccugaaaccguggacuuacaagcagucauggcaccuuaugcguguuauggcgugccuauugaagcaugagccggcgacuuagaccugacgugcgagcuuaaguugaaaaacggaggcggagcgaaagcgaguccgaauagggcggcauuaguacgucgggcuagacucgaaaccaggugagcuaagcaugaccagguugaaacccccgggggcggaggaccgaaccggugccugcugaaacagucucggaugaguuguguuuaggagugaaaagcuaaccgaaccuggagauagcuaguucuccccgaaauguauugagguacagccucggauguugaccauguccuguagagcacucacaaggcuaaaccuuaugaaacuccgaaggggcacgcguuuaguccgggagugaggcugcgagagcuaacuuccguagccgagagggaaacaacccagaccaucagcuaaggucccuaaaugaucgcucagugguuaaggaugugucgucgcgacagccaggagguuggcuuagagcagccacccuucaaagagugcguaauagcucacuggucgagugacgaugcgccgaaaaugaucggggcucaagugaucuaccgaagcuauggauucaacucguugucugguaggggagcguucaguccgcggagaagccauaccggaaggagugguggagccgacugaagugcggaugccggcaugaguaacgauaaaagaagugagaaucuucuucgccguaaggacaaggguuccuggggaagggucguccgcccagggaaagucgggaccuaaggugaggccgaacggcgcagccgauggacagcaggucaagauuccugcaccgaucaugugagugauggagggacgcauuacgcuauccaaugccaagcuauggcuaugcugguugguacgcucaagggcgaucgggucagaaaaucuaccgguugccucagacguaucgggagcuuccucggaagcgaaguuggaaacgcgacggugccaagaaaagcuucuaaacguugaaacaugauugcccguaccgcaaaccgacacagguguccgagugucaaugcacuaaggcgcgcgagagaacccucguuaaggaacuuugcaaucucaccccguaacuucggaagaagggguccccacgcuucgcguggggcgcagugaauaggcccaggcgacuguuuaccaaaaucacagcacucugccaacacgaacaguggacuauagggugugacgccugcccggugccggaaggucaaguggagcggugcaagcugcgaaaugaagccccggugaacggcuaagguagcgaaauuccuugucggguaaguuccgaccugcacgaaaggcguaacgaucugggcgcugucucaacgagggacucggugaaauugaauuggcuguaaagaugcggccuacccguagcaggacgaaaagaccccguggagcuuuacuauagucuggcauugggauucgggucuuggauuucuaaccugaaaaaucacuuucggggaccgugcuuggcggguaguuugacuggggcggucgccucccaaaauguaacggaggcgcccaaaggucaccucaagacgguuggaaaucgucuguagagcgcaaagguagaagguggcuugacugcgagacugacacgucgagcagggaggaaacucgggcuuagugaaccggugguaccguguggaagggccaucgaucaacggauaaaaguuaccccggggauaacaggcugaucucccccgagaguccauaucggcggggagguuuggcaccucgaugucggcucgucgcauccuggggcugaagaaggucccaaggguugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgugagacaguucggucucuauccgcuacgggcgcaggagaauugaggggaguugcuccuaguacgagaggaccggagugaacggaccgcuggucucccugcugucguaccaacggcacaugcaggguagcuauguccggaacggauaaccgcugaaagcaucuaagcgggaagccagccccaagaugaguucucccacugagguaagacucccggaagaccaccggguuaagaggccaggcgugcacgcauagcaauguguucagcggacuggugcucaucagucgaggucuugacc	<<<<<<<<......<<<<<<<<<<<.....<<..<<.<<<<<<<<<......<<<<<<.[...((.>>>.....<<<<<<...<<.))...]..>>......>>>>>>...>>>....<<<....>>><<<<<....>>>>><<<<....>>>>>>...<<<<<<.....<<....>>......>>>>>.>.........<<....>>...<<<<......<<.....>>.....>>>>...<<<...<<..<<<...<<<<<......>>>>>((......<<<.....))>>>...>>>....>>..<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..>>>......>>.>>>>>..>>..............<<....>>....>>.........<<<<....>>>>..................>>>>>>>>>>>.......<<<<<<<<<<.......>>>>>>>>>>...<............>.<<<<<<....<<<.<<<<<<<<<<..<<<...<<<....>>>...>>>...<<....>>...<........>.........>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<.....<<<<..>>>>......>>>...<<<..<.<<........>>.>.>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<.<<<<<<...<<<...<<<.<<<<.....>>>>.>>>..>>.>...>>>>>>.>.>>>..>>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<<<<<<.....<<<<<.<<...<<<<......>>>>...>>.......<.<<......>>.>.>>>>>....>>>>>>>>>.>>..........)))......>>>>>>.>>>...>>>>>>><..<<<<..>>>>..>....>>>>>><<<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>.>>.....>>>>>><......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<<..>>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<<<..<<...<<<<....<<<<..<<<..<<<<<.<<<<.<<...[[....>>>>>><<<<<<<.<<..<<<<.<<<<<...<<.....>>.>>>>>.>>>>..>>>>>>>>>...<<<<<....>>>>>....>>>>>...>>>...>>>>.........>>>>...>>......>>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<<....>>>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<.....<..>......>>>>><<<<<<<<...>>>>>>>>............<<<<<<<<<..<<...........>>..<<<<<<<.....<<<.....>>>......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<...<<...<<<<<....>>>>>...>>...>>>>>>>>..>>>>>.......<...........<<<<<.......>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.<<<.........<<<<.<<<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<...>>>>>>>>>...<<<<<<........>>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<....(((.>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.<<..>>>>..>>>>>>>>>.............>>>>..>>>>>>.......<<<<.<.<<<<<<.<.<<.......>>..>>>>>>>...>>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>........>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<....<<<...<<<<<<<<<<<.]].>>>>>>...>>>>>...>>>..>>>>>....<<.<..<<<<<...........>>>>>...>>>..>>>>.......>>>>>>>..<<.>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>>>>>>	(..(((((......((((((((((.....(((..((((((((((((.......(((((.....[[.))).....((((((...((.]]......))......))))))...)).....(((....)))(((((....)))))((((....))))))...((((((.........[.........))))).).........((....))...((((.........]..........))))...(((...((..(((...(((((......)))))[[(...).((......]].))...)))....))..(((((((((.[.....))))))))).......(.((].[[[[)).)...)))......)).)))))).))..............((....))....)).........((((....))))..(......)...).....)))))))))).....(.(((((((((.........))))))))).[.(.(........).).((((((....(((.((((((((((...((...(((....)))...))....((....))....(.......).........)))))))))))))..((.(...((((((.....(((((((((..((((....((((()))))....)[)))...((...(.((........)).)..))....))))))))).(.(((.....)))...)..))))))......).))..((((((....(((((....)))))(((((((((...((((.((((((...(((...(((.(((.......))).)))..)).)...)))))).).)))..))))))).))..(((((((.((......)).)))))))....(((......)))...((((.(((...((([[[...(.((((((.....(.....((..(.((((((.(..{..(((..(((..((..........))..))).....(..............)..)))....).)))))).).))..........]]].)....))))))))))...)))))))(..((......))..)....))))))(.(((((((.........(((((.((....)).)))))......)))))))..).....))))))(......((.....(.((((.......)))).)((((....((((..((..((((((....((.....))..)))))....[.((((..(...(((...(((....)))...)))...)....(((((........))))).]((((((.((..((...((((.....((((.(((..((((...(((.((...{{....))))).(((((((.((..((.(.(((((...((.....)).))))).).))..)))))))))...(((((....))))).....))))...)))..)))).(..).....))))...))......)).)))))))))).))).....((......)).)))).(((((....)))))..))))..((((....(((((((...........(........((((....(....).....)))).((((((((...))))))))(...).......(((((((((.].(...........)....((((((.....(.(.....).)......))))))...((((.(((..((.((((..(.....((...((((......))))...)).....)))))...))))).......(...........((((.........)))).....)....))))...)).))))))).).......))))))).)))))).....)).{..(((((.....]}.)))))..((((((((.(((..(......((((.((((((..(((((.(((.(((((.(((((((((...)))))))))...((((((........))))))....))))).)))..)))))..(((......[)))((((((..........]))))))(..(...(((((((.(.(((((.........)))))...).((.[.[[[))....)))))))...((....(((...{..)))....)).(((....))).).]]].].....(((((((.((..]]]]..))))))))).....)}......))))..))))))......((.((.(.((((((...((.......))...))))))...)))..).).......(((.((((((..(.(.(((((......)))))...).).(((((.....))))).....)))))..)...))).......((.((((....))).).))....)...)))))))))))[...(((((((...((((..(((((((.....(....)....))))))).(((..(.....(...(((((((((((.}}.))))))...)))))...)....).)))....((....((((.....}.......))))....))..))))..]....)))))))..((.))....(..((((((.......)))))....((((((((.(((.....((((....))))....)))..))))).)))...)..)....)))))..)	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit; RIBOSOMAL 23S RNA