3pio	X	2657	3.2473	RF02540,RF02541	URS000080DEF1_243230	21282615		0003735		0005840	243230	ggucaagauaguaaggguccacgguggaugcccuggcgcuggagccgaugaaggacgcgauuaccugcgaaaagccccgacgagcuggagauacgcuuugacucggggauguccgaauggggaaacccaccucguaagagguauccgcaaggaugggaacucagggaacugaaacaucucaguaccugaaggagaagaaagagaauucgauuccguuaguagcggcgagcgaacccggaucagcccaaucaagccgaaguggcuggaaagcuacaccucagaaggugagaguccuguaggcgaacgagaggucguuguucgugaaacgaugacugaauccgcgcggaccaccgcgcaaggcuaaauacucccagugaccgauagcgcauaguaccgugagggaaaggugaaaagaaccccgggaggggagugaaagagaaccugaaaccguggacuuacaagcagucauggcaccuuaugcguguuauggcgugccuauugaagcaugagccggcgacuuagaccugacgugcgagcuuaaguugaaaaacggaggcggagcgaaagcgaguccgaauagggcggcauuaguacgucgggcuagacucgaaaccaggugagcuaagcaugaccagguugaaacccccggggggcggaggaccgaaccggugccugcugaaacagucucggaugaguuguguuuaggagugaaaagcuaaccgaaccuggagauagcuaguucuccccgaaauguauugagguacagccucggauguugaccauguccuguagagcacucacaaggcuaaaccuuaugaaacuccgaaggggcacgcguuuaguccgggagugaggcugcgagagcuaacuuccguagccgagagggaaacaacccagaccaucagcuaaggucccuaaaugaucgcucagugguuaaggaugugucgucgcauagacagccaggagguuggcuuagaagcagccacccuucaaagagugcguaauagcucacuggucgagugacgaugcgccgaaaaugaucggggcucaagugaucuaccgaagcuauggauucaacucggaguugucugguaggggagcguucaguccgcggagaagccauaccggaaggagugguggagccgacugaagugcggaugccggcaugaguaacgauaaaagaagugagaaucuucuucgccguaaggacaaggguuccuggggaagggucguccgcccagggaaagucgggaccuaaggugaggccgaacggcgcagccgauggacagcaggucaagauuccugcaccgaucauguggagugauggagggacgcauuacgcuauccaaugccaagcuauggcuaugcugguugguacgcucaagggcgaucgggucagaaaaucuaccggucugccucagacguaucgggagcuuccucggaagcgaaguuggaaacgcgacggugccaagaaaagcuucuaaacguugaaacaugauugcccguaccgcaaaccgacacagguguccgagugucaaugcacuaaggcgcgcgagagaacccucguuaaggaacuuugcaaucucaccccguaacuucggaagaagggguccccacgcuucgcguggggcgcagugaauaggcccaggcgacuguuuaccaaaaucacagcacucugccaacacgaacaguggacguauagggugugacgccugcccggugccggaaggucaaguggagcggugcaagcugcgaaaugaagccccggugaacggcuaagguagcgaaauuccuugucggguaaguuccgaccugcacgaaaggcguaacgaucugggcgcugucucaacgagggacucggugaaauugaauuggcuguaaagaugcggccuacccguagcaggacgaaaagaccccguggagcuuuacuauagucuggcauugggauucggguuacuuggauuucuaaccugaaaaaucacuuucggggaccgugcuuggcggguaguuugacuggggcggucgccucccaaaauguaacggaggcgcccaaaggucaccucaagacgguuggaaaucgucuguagagcgcaaagguagaagguggcuugacugcgagacugacacgucgagcagggaggaaacucgggcuuagugaaccggugguaccguguggaagggccaucgaucaacggauaaaaguuaccccggggauaacaggcugaucucccccgagaguccauaucggcggggagguuuggcaccucgaugucggcucgucgcauccuggggcugaagaaggucccaaggguugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgugagacaguucggucucuauccgcuacgggcgcaggagaauugaggggaguugcuccuaguacgagaggaccggagugaacggaccgcuggucucccugcugucguaccaacggcacaugcaggguagcuauguccggaacggauaaccgcugaaagcaucuaagcgggaagccagccccaagaugaguucucccacugagguaagacucccggaagaccaccggguuaagaggccaggcgugcacgcauagcaauguguucagcggacuggugcucaucagucgaggucuugacc	.<<<<<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<<<<<.((..((.>>>.....<<<<<<...<<.))..))..>>......>>>>>>...>>>....<<<....>>><<<<<....>>>>><<<<....>>>>>>...<<<<<<.....<<....>>......>>>>>.>.........<<....>>...<<<<......<<.....>>.....>>>>...<<<...<<..<<<...<<<<<......>>>>>((......<<<.....))>>>...>>>....>>..<<<<<<<<.........>>>>>>>>......<<<<<..((((>>>>>..>>>......>>.>>>>>>.>>..............<<....>>....>>.........<<<<....>>>>..................>>>>>>>>>>>.......<<<<<<<<<<.......>>>>>>>>>>...<............>.<<<<<<....<<<.<<<<<<<<<<..<<<...<<<....>>>...>>>...<<....>>...<........>.........>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<.....<<<<<.>>>>>......>>>...<<<..<.<<........>>.>.>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<.<<<<<<...<<<...<<<.<<<<.....>>>>.>>>..>>.>...>>>>>>.>.>>>..>>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<<<<<<........<<<<<.<<...<<<<.......>>>>...>>.........<<......>>...>>>>>....>>>>>>>>>.>>..........)))......>>>>>>.>>>...>>>>>>><..<<<<.....>>>>..>....>>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<<..>>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<<<...<<...<<<<....<<<<..<<<..<<<<<.<<<<.<<...[[....>>>>>><<<<<<<.<<..<<<.<<<<<<...<<.....>>.>>>>>>..>>>..>>>>>>>>>...<<<<<....>>>>>....>>>>>...>>>...>>>>.........>>>>...>>......>>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<<....>>>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<....<<..>>.....>>>>><<<<<<<<...>>>>>>>>............<<<<<<<<<..<<...........>>..<<<<<<<.....<<<.....>>>.......>>>>>>>.<<<<<..<<..<<<<<<<..<<<...<<...<<<<<....>>>>>...>>...>>>>>>>>..>>>>........<...........<<<<<.......>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.<<<.........<<<<.<<<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<<<.>>>>>>>>>>>...<<<<<<........>>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<....(((.>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.<<..))))..>>>>>>>>>.............>>>>..>>>>>>.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>........>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<....<<<...<<<<<<<<<<<.]].>>>>>>...>>>>>...>>>..>>>>>....<<....<<<<<...........>>>>>....>>..>>>>.......>>>>>>>..<<.>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>>>>>.	(..(((((......((((((((((.....(((..(...((((.(((......((((((.[......)))......(((((...((......]..))......)))))....)))....(((....)))(((((....)))))(.((....)).)))...((((((.....(...[..)......))))).).........((....))...((((......((.]...)).....))))...(((.......(((...(((((......))))).[(...).((......]..))...)))........((((((((..[......)))))))).......(.((].[[[[)).)...)))......)..))))....)..............((....))....)).........((((....)))).............).....)))))))))).....(.((((((((((.......)))))))))).[.(.(........).).((((((....(((.((((((((((..(.(...(((....)))...).)...((....))...((......)).........)))))))))))))..((.(...((((((.....((((((.(((.((((....(((((.)))))....).)))...(((..(.((........)).).)))..).)).)))))).(.(((.....)))...)..))))))......).))..((((((....(((((....)))))(((((((((....(.(.(((((....(((...(((.(((.......))).)))..)).)....))))).)..)...))))))).))..(((((((.((......)).)))))))....(((......)))...((((.(((...((([[[...(.((((((.....(.....((..(((((..(.(........(((...((..((...........))..))........................)))....).)..))))).))..........]]].)....))))))))))...)))))))(..((...(.)...))..)....))))))(.(((((((.........(((((.((....)).)))))......)))))))..).....))))))(......((.....((((((.......))))))((((....((((..((..(((((((...((.....)).))))))....[.((((.((...(((...(((....)))...)))...))....(((..........)))..]((((((.((...((...((((....(((((.(((..(((((.((((......{{......))))(((((((.((..((.(.(.((....(.......)..)).)..).))..)))))))))...(((((....)))))....)))))...)))..)))))(..).....))))...))......)).)))))))))).))).....((......)).)))).(((((....)))))..))))..((((....((((((((.((..(....(.......(((((....(.[..).....)))))((((((((...))))))))(...).......(((((((((...(...........)...(((((((.....(((.....))).......))))))).]((((.(((.....((((..((.............(....).............)))))).....))).......((..........(((((.......)))))..)..)....))))...)).))))))).)..))).)))))))).)))))).....)).{..(((((.....]}.)))))..((((((((.(((.........((((.((((((..(((((.(.(.(((((.((((.((((.....))).)))))...((((((........))))))....))))).).)..)))))..(((......[)))((((((..........]))))))(.((...((((((..(.(((((.........)))))...).((.[.[[[)).....))))))...((.....((...{..)).....)).(((....))).))]]].].....(((((((.((..]]]]..))))))))).....)}......))))..))))))......(((((.(.((((((...((.......))...))))))...)))).).)......((((.((((((..(((((((((......))))))..))).(((((.....))))).....)))))..)...))).).....(((((((....))).))))........)))))))))))[...(((((((...((((..(((((((.....(....)....))))))).((((.(...(((...(((((((((((.}}.))))))...)))))...)))..)))))....((....((((.............))))....))..))))..]....)))))))..((.))....(((((((((.......)))))....((((((((.(((....(((((....)))))...)))..))))).)))...))))....)))))..)	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit; RIBOSOMAL 23S RNA
3pip	X	2644	3.45	RF02540,RF02541	URS000080DEF1_243230	21282615		0003735		0005840	243230	ggucaagauaguaaggguccacgguggaugcccuggcgcuggagccgaugaaggacgcgauuaccugcgaaaagccccgacgagcuggagauacgcuuugacucggggauguccgaauggggaaacccaccucguaagagguauccgcaaggaugggaacucagggaacugaaacaucucaguaccugaaggagaagaaagagaauucgauuccguuaguagcggcgagcgaacccggaucagcccaaucaagccgaaguggcuggaaagcuacaccucagaaggugagaguccuguaggcgaacgagaggucguuguucgugaaacgaugacugaauccgcgcggaccaccgcgcaaggcuaaauacucccagugaccgauagcgcauaguaccgugagggaaaggugaaaagaaccccgggaggggagugaaagagaaccugaaaccguggacuuacaagcagucauggcaccuuaugcguguuauggcgugccuauugaagcaugagccggcgacuuagaccugacgugcgagcuuaaguugaaaaacggaggcggagcgaaagcgaguccgaauagggcggcauuaguacgucgggcuagacucgaaaccaggugagcuaagcaugaccagguugaaacccccgggggcggaggaccgaaccggugccugcugaaacagucucggaugaguuguguuuaggagugaaaagcuaaccgaaccuggagauagcuaguucuccccgaaauguauugagguacagccucggauguugaccauguccuguagagcacucacaaggcuaaaccuuaugaaacuccgaaggggcacgcguuuaguccgggagugaggcugcgagagcuaacuuccguagccgagagggaaacaacccagaccaucagcuaaggucccuaaaugaucgcucagugguuaaggaugugucgucgcgacagccaggagguuggcuuagagcagccacccuucaaagagugcguaauagcucacuggucgagugacgaugcgccgaaaaugaucggggcucaagugaucuaccgaagcuauggauucaacucguugucugguaggggagcguucaguccgcggagaagccauaccggaaggagugguggagccgacugaagugcggaugccggcaugaguaacgauaaaagaagugagaaucuucuucgccguaaggacaaggguuccuggggaagggucguccgcccagggaaagucgggaccuaaggugaggccgaacggcgcagccgauggacagcaggucaagauuccugcaccgaucaugugagugauggagggacgcauuacgcuauccaaugccaagcuauggcuaugcugguugguacgcucaagggcgaucgggucagaaaaucuaccgguugccucagacguaucgggagcuuccucggaagcgaaguuggaaacgcgacggugccaagaaaagcuucuaaacguugaaacaugauugcccguaccgcaaaccgacacagguguccgagugucaaugcacuaaggcgcgcgagagaacccucguuaaggaacuuugcaaucucaccccguaacuucggaagaagggguccccacgcuucgcguggggcgcagugaauaggcccaggcgacuguuuaccaaaaucacagcacucugccaacacgaacaguggacuauagggugugacgccugcccggugccggaaggucaaguggagcggugcaagcugcgaaaugaagccccggugaacggcuaagguagcgaaauuccuugucggguaaguuccgaccugcacgaaaggcguaacgaucugggcgcugucucaacgagggacucggugaaauugaauuggcuguaaagaugcggccuacccguagcaggacgaaaagaccccguggagcuuuacuauagucuggcauugggauucgggucuuggauuucuaaccugaaaaaucacuuucggggaccgugcuuggcggguaguuugacuggggcggucgccucccaaaauguaacggaggcgcccaaaggucaccucaagacgguuggaaaucgucuguagagcgcaaagguagaagguggcuugacugcgagacugacacgucgagcagggaggaaacucgggcuuagugaaccggugguaccguguggaagggccaucgaucaacggauaaaaguuaccccggggauaacaggcugaucucccccgagaguccauaucggcggggagguuuggcaccucgaugucggcucgucgcauccuggggcugaagaaggucccaaggguugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgugagacaguucggucucuauccgcuacgggcgcaggagaauugaggggaguugcuccuaguacgagaggaccggagugaacggaccgcuggucucccugcugucguaccaacggcacaugcaggguagcuauguccggaacggauaaccgcugaaagcaucuaagcgggaagccagccccaagaugaguucucccacugagguaagacucccggaagaccaccggguuaagaggccaggcgugcacgcauagcaauguguucagcggacuggugcucaucagucgaggucuugacc	<<<<<<<<......<<<<<<<<<<<.....<<..<<.<<<<<<<<<......<<<<<<.[...((.>>>.....<<<<<<...<<.))...]..>>......>>>>>>...>>>....<<<....>>><<<<<....>>>>><<<<....>>>>>>...<<<<<<.....<<....>>......>>>>>.>.........<<....>>...<<<<......<<.....>>.....>>>>...<<<...<<..<<<...<<<<<......>>>>>((......<<<.....))>>>...>>>....>>..<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..>>>......>>.>>>>>..>>..............<<....>>....>>.........<<<<....>>>>..................>>>>>>>>>>>.......<<<<<<<<<<.......>>>>>>>>>>...<............>.<<<<<<....<<<.<<<<<<<<<<..<<<...<<<....>>>...>>>...<<....>>...<........>.........>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<.....<<<<..>>>>......>>>...<<<..<.<<........>>.>.>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<.<<<<<<...<<<...<<<.<<<<.....>>>>.>>>..>>.>...>>>>>>.>.>>>..>>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<<<<<<.....<<<<<.<<...<<<<......>>>>...>>.......<.<<......>>.>.>>>>>....>>>>>>>>>.>>..........)))......>>>>>>.>>>...>>>>>>><..<<<<..>>>>..>....>>>>>><<<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>.>>.....>>>>>><......<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<<..>>>>...>>>...>>...<<<<<........>>>>>))<<<<<<<<<..<<...<<<<....<<<<..<<<..<<<<<.<<<<.<<...[[....>>>>>><<<<<<<.<<..<<<<.<<<<<...<<.....>>.>>>>>.>>>>..>>>>>>>>>...<<<<<....>>>>>....>>>>>...>>>...>>>>.........>>>>...>>......>>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<<....>>>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<.....<..>......>>>>><<<<<<<<...>>>>>>>>............<<<<<<<<<..<<...........>>..<<<<<<<.....<<<.....>>>......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<...<<...<<<<<....>>>>>...>>...>>>>>>>>..>>>>>.......<...........<<<<<.......>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.<<<.........<<<<.<<<<<<..<<<<<.<<<.<<<<<.<<<<<<<<<...>>>>>>>>>...<<<<<<........>>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<....(((.>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.<<..>>>>..>>>>>>>>>.............>>>>..>>>>>>.......<<<<.<.<<<<<<.<.<<.......>>..>>>>>>>...>>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>........>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<....<<<...<<<<<<<<<<<.]].>>>>>>...>>>>>...>>>..>>>>>....<<.<..<<<<<...........>>>>>...>>>..>>>>.......>>>>>>>..<<.>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>>>>>>	(..(((((......((((((((((.....(((..((((((((((((.......(((((.....[[.))).....((((((...((.]]......))......))))))...)).....(((....)))(((((....)))))((((....))))))...((((((.........[.........))))).).........((....))...((((.........]..........))))...(((...((..(((...(((((......)))))[[(...).((......]].))...)))....))..(((((((((.[.....))))))))).......(.((].[[[[)).)...)))......)).)))))).))..............((....))....)).........((((....))))..(......)...).....)))))))))).....(.(((((((((.........))))))))).[.(.(........).).((((((....(((.((((((((((...((...(((....)))...))....((....))....(.......).........)))))))))))))..((.(...((((((.....(((((((((..((((....((((()))))....)[)))...((...(.((........)).)..))....))))))))).(.(((.....)))...)..))))))......).))..((((((....(((((....)))))(((((((((...((((.((((((...(((...(((.(((.......))).)))..)).)...)))))).).)))..))))))).))..(((((((.((......)).)))))))....(((......)))...((((.(((...((([[[...(.((((((.....(.....((..(.((((((.(..{..(((..(((..((..........))..))).....(..............)..)))....).)))))).).))..........]]].)....))))))))))...)))))))(..((......))..)....))))))(.(((((((.........(((((.((....)).)))))......)))))))..).....))))))(......((.....(.((((.......)))).)((((....((((..((..((((((....((.....))..)))))....[.((((..(...(((...(((....)))...)))...)....(((((........))))).]((((((.((..((...((((.....((((.(((..((((...(((.((...{{....))))).(((((((.((..((.(.(((((...((.....)).))))).).))..)))))))))...(((((....))))).....))))...)))..)))).(..).....))))...))......)).)))))))))).))).....((......)).)))).(((((....)))))..))))..((((....(((((((...........(........((((....(....).....)))).((((((((...))))))))(...).......(((((((((.].(...........)....((((((.....(.(.....).)......))))))...((((.(((..((.((((..(.....((...((((......))))...)).....)))))...))))).......(...........((((.........)))).....)....))))...)).))))))).).......))))))).)))))).....)).{..(((((.....]}.)))))..((((((((.(((..(......((((.((((((..(((((.(((.(((((.(((((((((...)))))))))...((((((........))))))....))))).)))..)))))..(((......[)))((((((..........]))))))(..(...(((((((.(.(((((.........)))))...).((.[.[[[))....)))))))...((....(((...{..)))....)).(((....))).).]]].].....(((((((.((..]]]]..))))))))).....)}......))))..))))))......((.((.(.((((((...((.......))...))))))...)))..).).......(((.((((((..(.(.(((((......)))))...).).(((((.....))))).....)))))..)...))).......((.((((....))).).))....)...)))))))))))[...(((((((...((((..(((((((.....(....)....))))))).(((..(.....(...(((((((((((.}}.))))))...)))))...)....).)))....((....((((.....}.......))))....))..))))..]....)))))))..((.))....(..((((((.......)))))....((((((((.(((.....((((....))))....)))..))))).)))...)..)....)))))..)	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit; RIBOSOMAL 23S RNA