Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (293 IgG)# Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO)# Peptides (by Search Engine): C2 Sequest HT (293 WT)# Peptides (by Search Engine): D2 Sequest HT (293 H KO)# PSMs (by Search Engine): A2 Sequest HT (293 IgG)# PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO)# PSMs (by Search Engine): C2 Sequest HT (293 WT)# PSMs (by Search Engine): D2 Sequest HT (293 H KO)Abundance: F1: Sample, 293 IgGAbundance: F2: Sample, 293 Sel1L KOAbundance: F3: Sample, 293 WTAbundance: F4: Sample, 293 H KOAbundances Count: F1: Sample, 293 IgGAbundances Count: F2: Sample, 293 Sel1L KOAbundances Count: F3: Sample, 293 WTAbundances Count: F4: Sample, 293 H KOModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighO14965Aurora kinase A OS=Homo sapiens OX=9606 GN=AURKA PE=1 SV=2017.9731966640345.89.3966456637.437517837992.889020750263754.93752611cell division;cell growth;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimuluscytoplasm;cytoskeleton;cytosol;nucleuscatalytic activity;nucleotide binding;protein binding"Pf00069, Pf01636, Pf07714, Pf14531"6790AURKA20FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Interaction between PHLDA1 and AURKA; Regulation of PLK1 Activity at G2/M Transition; AURKA Activation by TPX2; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; SUMOylation of DNA replication proteins; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of TP53 Activity through PhosphorylationOocyte meiosis0

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