Protein FDR Confidence: Combined | Accession | Description | Exp. q-value: Combined | Sum PEP Score | Coverage [%] | # Peptides | # PSMs | # Unique Peptides | # AAs | MW [kDa] | calc. pI | # Peptides (by Search Engine): A2 Sequest HT (293 IgG) | # Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO) | # Peptides (by Search Engine): C2 Sequest HT (293 WT) | # Peptides (by Search Engine): D2 Sequest HT (293 H KO) | # PSMs (by Search Engine): A2 Sequest HT (293 IgG) | # PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO) | # PSMs (by Search Engine): C2 Sequest HT (293 WT) | # PSMs (by Search Engine): D2 Sequest HT (293 H KO) | Abundance: F1: Sample, 293 IgG | Abundance: F2: Sample, 293 Sel1L KO | Abundance: F3: Sample, 293 WT | Abundance: F4: Sample, 293 H KO | Abundances Count: F1: Sample, 293 IgG | Abundances Count: F2: Sample, 293 Sel1L KO | Abundances Count: F3: Sample, 293 WT | Abundances Count: F4: Sample, 293 H KO | Modifications | Biological Process | Cellular Component | Molecular Function | Pfam IDs | Entrez Gene ID | Ensembl Gene ID | Gene Symbol | Chromosome | Reactome Pathways | KEGG Pathways | # Razor Peptides |
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High | O14965 | Aurora kinase A OS=Homo sapiens OX=9606 GN=AURKA PE=1 SV=2 | 0 | 17.973 | 19 | 6 | 6 | 6 | 403 | 45.8 | 9.39 | 6 | 6 | 456637.4375 | 17837992.88 | 9020750 | 263754.9375 | 2 | 6 | 1 | 1 | cell division;cell growth;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus | cytoplasm;cytoskeleton;cytosol;nucleus | catalytic activity;nucleotide binding;protein binding | "Pf00069, Pf01636, Pf07714, Pf14531" | 6790 | AURKA | 20 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Interaction between PHLDA1 and AURKA; Regulation of PLK1 Activity at G2/M Transition; AURKA Activation by TPX2; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; SUMOylation of DNA replication proteins; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of TP53 Activity through Phosphorylation | Oocyte meiosis | 0 |