Protein FDR Confidence: Combined | Accession | Description | Exp. q-value: Combined | Sum PEP Score | Coverage [%] | # Peptides | # PSMs | # Unique Peptides | # AAs | MW [kDa] | calc. pI | # Peptides (by Search Engine): A2 Sequest HT (293 IgG) | # Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO) | # Peptides (by Search Engine): C2 Sequest HT (293 WT) | # Peptides (by Search Engine): D2 Sequest HT (293 H KO) | # PSMs (by Search Engine): A2 Sequest HT (293 IgG) | # PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO) | # PSMs (by Search Engine): C2 Sequest HT (293 WT) | # PSMs (by Search Engine): D2 Sequest HT (293 H KO) | Abundance: F1: Sample, 293 IgG | Abundance: F2: Sample, 293 Sel1L KO | Abundance: F3: Sample, 293 WT | Abundance: F4: Sample, 293 H KO | Abundances Count: F1: Sample, 293 IgG | Abundances Count: F2: Sample, 293 Sel1L KO | Abundances Count: F3: Sample, 293 WT | Abundances Count: F4: Sample, 293 H KO | Modifications | Biological Process | Cellular Component | Molecular Function | Pfam IDs | Entrez Gene ID | Ensembl Gene ID | Gene Symbol | Chromosome | Reactome Pathways | KEGG Pathways | # Razor Peptides |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High | O95714 | E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2 | 0 | 52.769 | 5 | 20 | 32 | 20 | 4834 | 526.9 | 6.28 | 5 | 4 | 7 | 12 | 6 | 4 | 8 | 14 | 1886315.229 | 23508033.3 | 13978057.78 | 18516150.28 | 6 | 10 | 12 | 14 | metabolic process;response to stimulus;transport | cytoplasm;cytoskeleton;membrane;nucleus | catalytic activity;metal ion binding;protein binding | "Pf00173, Pf00415, Pf00569, Pf00632, Pf03256, Pf06701, Pf11515, Pf13540" | 8924 | ENSG00000128731.15 | HERC2 | 15 | G2/M DNA damage checkpoint; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; Nonhomologous End-Joining (NHEJ); Antigen processing: Ubiquitination & Proteasome degradation; SUMOylation of DNA damage response and repair proteins | Ubiquitin mediated proteolysis | 0 |