| Protein FDR Confidence: Combined | Accession | Description | Exp. q-value: Combined | Sum PEP Score | Coverage [%] | # Peptides | # PSMs | # Unique Peptides | # AAs | MW [kDa] | calc. pI | # Peptides (by Search Engine): A2 Sequest HT (293 IgG) | # Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO) | # Peptides (by Search Engine): C2 Sequest HT (293 WT) | # Peptides (by Search Engine): D2 Sequest HT (293 H KO) | # PSMs (by Search Engine): A2 Sequest HT (293 IgG) | # PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO) | # PSMs (by Search Engine): C2 Sequest HT (293 WT) | # PSMs (by Search Engine): D2 Sequest HT (293 H KO) | Abundance: F1: Sample, 293 IgG | Abundance: F2: Sample, 293 Sel1L KO | Abundance: F3: Sample, 293 WT | Abundance: F4: Sample, 293 H KO | Abundances Count: F1: Sample, 293 IgG | Abundances Count: F2: Sample, 293 Sel1L KO | Abundances Count: F3: Sample, 293 WT | Abundances Count: F4: Sample, 293 H KO | Modifications | Biological Process | Cellular Component | Molecular Function | Pfam IDs | Entrez Gene ID | Ensembl Gene ID | Gene Symbol | Chromosome | Reactome Pathways | KEGG Pathways | # Razor Peptides |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| High | P09429 | High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 | 0 | 28.848 | 35 | 5 | 6 | 4 | 215 | 24.9 | 5.74 | 5 | 6 | 263271.8438 | 17500537 | 353789.2188 | 506621.1875 | 1 | 4 | 1 | 1 | cell differentiation;cell organization and biogenesis;cell proliferation;cellular component movement;cellular homeostasis;defense response;metabolic process;regulation of biological process;response to stimulus;transport | cell surface;chromosome;cytoplasm;endosome;extracellular;membrane;nucleus;organelle lumen | catalytic activity;DNA binding;enzyme regulator activity;protein binding;RNA binding | "Pf00505, Pf09011" | 3146 | ENSG00000189403.14 | HMGB1 | 13 | TRAF6 mediated NF-kB activation; Advanced glycosylation endproduct receptor signaling; TAK1 activates NFkB by phosphorylation and activation of IKKs complex; RIP-mediated NFkB activation via ZBP1; Activated TLR4 signalling; Interleukin-1 family signaling; Neutrophil degranulation; Regulation of TLR by endogenous ligand; DEx/H-box helicases activate type I IFN and inflammatory cytokines production ; Activation of DNA fragmentation factor | Base excision repair | 1 |