Protein FDR Confidence: Combined | Accession | Description | Exp. q-value: Combined | Sum PEP Score | Coverage [%] | # Peptides | # PSMs | # Unique Peptides | # AAs | MW [kDa] | calc. pI | # Peptides (by Search Engine): A2 Sequest HT (293 IgG) | # Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO) | # Peptides (by Search Engine): C2 Sequest HT (293 WT) | # Peptides (by Search Engine): D2 Sequest HT (293 H KO) | # PSMs (by Search Engine): A2 Sequest HT (293 IgG) | # PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO) | # PSMs (by Search Engine): C2 Sequest HT (293 WT) | # PSMs (by Search Engine): D2 Sequest HT (293 H KO) | Abundance: F1: Sample, 293 IgG | Abundance: F2: Sample, 293 Sel1L KO | Abundance: F3: Sample, 293 WT | Abundance: F4: Sample, 293 H KO | Abundances Count: F1: Sample, 293 IgG | Abundances Count: F2: Sample, 293 Sel1L KO | Abundances Count: F3: Sample, 293 WT | Abundances Count: F4: Sample, 293 H KO | Modifications | Biological Process | Cellular Component | Molecular Function | Pfam IDs | Entrez Gene ID | Ensembl Gene ID | Gene Symbol | Chromosome | Reactome Pathways | KEGG Pathways | # Razor Peptides |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High | P19474 | E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 | 0 | 190.675 | 60 | 32 | 217 | 32 | 475 | 54.1 | 6.38 | 23 | 13 | 29 | 32 | 53 | 19 | 69 | 76 | 125396118 | 360514084.4 | 521717103.1 | 473507226.6 | 26 | 24 | 35 | 35 | cell organization and biogenesis;defense response;metabolic process;regulation of biological process;response to stimulus | cytoplasm;cytosol;nucleus;vacuole | catalytic activity;DNA binding;metal ion binding;protein binding;RNA binding | "Pf00097, Pf00622, Pf00643, Pf11789, Pf12128, Pf12678, Pf13445, Pf13639, Pf13765, Pf13920, Pf13923, Pf14570, Pf14634, Pf14835, Pf15227" | 6737 | ENSG00000132109.9 | TRIM21 | 11 | STING mediated induction of host immune responses; Antigen processing: Ubiquitination & Proteasome degradation; Interferon gamma signaling; Regulation of innate immune responses to cytosolic DNA | Systemic lupus erythematosus | 0 |