High | P48729 | Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2 | 0 | 39.013 | 33 | 9 | 14 | 9 | 337 | 38.9 | 9.57 | 1 | 8 | | | 1 | 13 | | | 1422204.584 | 41276416 | 1972405.125 | 1561067.063 | 2 | 8 | 1 | 3 | | cell division;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport | chromosome;cytoplasm;cytoskeleton;cytosol;membrane;nucleus | catalytic activity;nucleotide binding;protein binding | "Pf00069, Pf07714" | 1452 | ENSG00000113712.17 | CSNK1A1 | 5 | S37 mutants of beta-catenin aren't phosphorylated; Beta-catenin phosphorylation cascade; AXIN missense mutants destabilize the destruction complex; S33 mutants of beta-catenin aren't phosphorylated; Disassembly of the destruction complex and recruitment of AXIN to the membrane; APC truncation mutants have impaired AXIN binding; S45 mutants of beta-catenin aren't phosphorylated; GLI3 is processed to GLI3R by the proteasome; Misspliced GSK3beta mutants stabilize beta-catenin; Activation of SMO; Degradation of GLI2 by the proteasome; T41 mutants of beta-catenin aren't phosphorylated; Truncations of AMER1 destabilize the destruction complex | Breast cancer; Wnt signaling pathway; Hedgehog signaling pathway | 0 |