Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (293 IgG)	# Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# Peptides (by Search Engine): C2 Sequest HT (293 WT)	# Peptides (by Search Engine): D2 Sequest HT (293 H KO)	# PSMs (by Search Engine): A2 Sequest HT (293 IgG)	# PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# PSMs (by Search Engine): C2 Sequest HT (293 WT)	# PSMs (by Search Engine): D2 Sequest HT (293 H KO)	Abundance: F1: Sample, 293 IgG	Abundance: F2: Sample, 293 Sel1L KO	Abundance: F3: Sample, 293 WT	Abundance: F4: Sample, 293 H KO	Abundances Count: F1: Sample, 293 IgG	Abundances Count: F2: Sample, 293 Sel1L KO	Abundances Count: F3: Sample, 293 WT	Abundances Count: F4: Sample, 293 H KO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P53350	Serine/threonine-protein kinase PLK1 OS=Homo sapiens OX=9606 GN=PLK1 PE=1 SV=1	0	26.204	15	7	12	7	603	68.2	8.91		6	1	3		7	1	4	2101.209229	14722261.63	2616495.688	3269901.531	1	6	3	5		cell division;cell organization and biogenesis;cell proliferation;metabolic process;regulation of biological process;response to stimulus	chromosome;cytoplasm;cytoskeleton;cytosol;nucleus	catalytic activity;metal ion binding;nucleotide binding;protein binding	"Pf00069, Pf00659, Pf07714, Pf14531"	5347	ENSG00000166851.14	PLK1	16	"Regulation of PLK1 Activity at G2/M Transition; AURKA Activation by TPX2; Anchoring of the basal body to the plasma membrane; Polo-like kinase mediated events; Phosphorylation of Emi1; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Phosphorylation of the APC/C; Cyclin A/B1/B2 associated events during G2/M transition; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Condensation of Prophase Chromosomes; RHO GTPases Activate Formins; Activation of NIMA Kinases NEK9, NEK6, NEK7; Golgi Cisternae Pericentriolar Stack Reorganization; The role of GTSE1 in G2/M progression after G2 checkpoint; Mitotic Metaphase/Anaphase Transition; Mitotic Telophase/Cytokinesis"	FoxO signaling pathway; Progesterone-mediated oocyte maturation; Oocyte meiosis; Cell cycle	0

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