Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (293 IgG)	# Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# Peptides (by Search Engine): C2 Sequest HT (293 WT)	# Peptides (by Search Engine): D2 Sequest HT (293 H KO)	# PSMs (by Search Engine): A2 Sequest HT (293 IgG)	# PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# PSMs (by Search Engine): C2 Sequest HT (293 WT)	# PSMs (by Search Engine): D2 Sequest HT (293 H KO)	Abundance: F1: Sample, 293 IgG	Abundance: F2: Sample, 293 Sel1L KO	Abundance: F3: Sample, 293 WT	Abundance: F4: Sample, 293 H KO	Abundances Count: F1: Sample, 293 IgG	Abundances Count: F2: Sample, 293 Sel1L KO	Abundances Count: F3: Sample, 293 WT	Abundances Count: F4: Sample, 293 H KO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P62258	14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1	0	103.128	67	21	104	18	255	29.2	4.74	2	8	19	18	2	13	47	42	1745496.891	81583600.84	269477931.7	236896418.6	4	8	22	23	Acetyl [N-Term]	cell organization and biogenesis;cellular component movement;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport	cytoplasm;cytosol;membrane;mitochondrion;nucleus	protein binding;RNA binding	Pf00244	7531	ENSG00000108953.16; ENSG00000274474.3	YWHAE	17; CHR_HSCHR17_2_CTG2	Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; NADE modulates death signalling; Translocation of GLUT4 to the plasma membrane; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Signaling by Hippo; AURKA Activation by TPX2; Anchoring of the basal body to the plasma membrane; Regulation of HSF1-mediated heat shock response; Activation of BAD and translocation to mitochondria ; Recruitment of mitotic centrosome proteins and complexes; RAB GEFs exchange GTP for GDP on RABs; HSF1 activation; TP53 Regulates Metabolic Genes; Signalling by NGF; RHO GTPases activate PKNs	Viral carcinogenesis; Epstein-Barr virus infection; Neurotrophin signaling pathway; Hippo signaling pathway; Oocyte meiosis; Cell cycle; PI3K-Akt signaling pathway	3

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