Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (293 IgG)	# Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# Peptides (by Search Engine): C2 Sequest HT (293 WT)	# Peptides (by Search Engine): D2 Sequest HT (293 H KO)	# PSMs (by Search Engine): A2 Sequest HT (293 IgG)	# PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# PSMs (by Search Engine): C2 Sequest HT (293 WT)	# PSMs (by Search Engine): D2 Sequest HT (293 H KO)	Abundance: F1: Sample, 293 IgG	Abundance: F2: Sample, 293 Sel1L KO	Abundance: F3: Sample, 293 WT	Abundance: F4: Sample, 293 H KO	Abundances Count: F1: Sample, 293 IgG	Abundances Count: F2: Sample, 293 Sel1L KO	Abundances Count: F3: Sample, 293 WT	Abundances Count: F4: Sample, 293 H KO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	P84022	Mothers against decapentaplegic homolog 3 OS=Homo sapiens OX=9606 GN=SMAD3 PE=1 SV=1	0	6.866	6	2	2	2	425	48.1	7.15		2				2				1512011.375	716477.375	16116.79688		1	1	1	Met-loss+Acetyl [N-Term]	cell differentiation;cell organization and biogenesis;cellular homeostasis;metabolic process;regulation of biological process;response to stimulus;transport	cytoplasm;cytosol;membrane;nucleus	DNA binding;metal ion binding;protein binding;RNA binding;signal transducer activity	"Pf03165, Pf03166"	4088	ENSG00000166949.15	SMAD3	15	Signaling by NODAL; SMAD2/3 Phosphorylation Motif Mutants in Cancer; RUNX3 regulates BCL2L11 (BIM) transcription; Ub-specific processing proteases; Downregulation of TGF-beta receptor signaling; SMAD4 MH2 Domain Mutants in Cancer; Signaling by Activin; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Downregulation of SMAD2/3:SMAD4 transcriptional activity; SMAD2/3 MH2 Domain Mutants in Cancer; TGFBR1 KD Mutants in Cancer; RUNX3 regulates CDKN1A transcription	Chagas disease (American trypanosomiasis); Endocytosis; TGF-beta signaling pathway; Inflammatory bowel disease (IBD); Hepatitis B; Pancreatic cancer; FoxO signaling pathway; Chronic myeloid leukemia; Hippo signaling pathway; Colorectal cancer; Pathways in cancer; AGE-RAGE signaling pathway in diabetic complications; HTLV-I infection; Wnt signaling pathway; Adherens junction; Cell cycle; Signaling pathways regulating pluripotency of stem cells	0

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