High | Q12834 | Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 | 0 | 11.786 | 12 | 4 | 4 | 4 | 499 | 54.7 | 9.23 | | 4 | | | | 4 | | | 578690.8125 | 3760432 | 311762.6563 | | 1 | 2 | 1 | | | cell differentiation;cell division;cell organization and biogenesis;metabolic process;regulation of biological process | cytoplasm;cytoskeleton;cytosol | enzyme regulator activity;protein binding | Pf00400 | 991 | ENSG00000117399.13 | CDC20 | 1 | Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Ub-specific processing proteases; Phosphorylation of Emi1; APC-Cdc20 mediated degradation of Nek2A; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; SCF-beta-TrCP mediated degradation of Emi1; Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; RHO GTPases Activate Formins; Cdc20:Phospho-APC/C mediated degradation of Cyclin A | Viral carcinogenesis; Ubiquitin mediated proteolysis; HTLV-I infection; Oocyte meiosis; Cell cycle | 0 |