Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (293 IgG)# Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO)# Peptides (by Search Engine): C2 Sequest HT (293 WT)# Peptides (by Search Engine): D2 Sequest HT (293 H KO)# PSMs (by Search Engine): A2 Sequest HT (293 IgG)# PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO)# PSMs (by Search Engine): C2 Sequest HT (293 WT)# PSMs (by Search Engine): D2 Sequest HT (293 H KO)Abundance: F1: Sample, 293 IgGAbundance: F2: Sample, 293 Sel1L KOAbundance: F3: Sample, 293 WTAbundance: F4: Sample, 293 H KOAbundances Count: F1: Sample, 293 IgGAbundances Count: F2: Sample, 293 Sel1L KOAbundances Count: F3: Sample, 293 WTAbundances Count: F4: Sample, 293 H KOModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighQ13114TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=20.0032.751422256864.47.9122576798.9688468843.3438169657.5469211cell death;defense response;metabolic process;regulation of biological process;response to stimuluscytoplasm;cytosol;endosome;mitochondrioncatalytic activity;metal ion binding;protein binding;signal transducer activity"Pf00097, Pf00917, Pf02176, Pf05557, Pf10174"7187ENSG00000131323.14TRAF314TRAF3 deficiency - HSE; TICAM1-dependent activation of IRF3/IRF7; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon; Negative regulators of DDX58/IFIH1 signaling; TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; Activated TLR4 signallingViral carcinogenesis; TNF signaling pathway; NOD-like receptor signaling pathway; Epstein-Barr virus infection; Pathways in cancer; NF-kappa B signaling pathway; Small cell lung cancer; Toll-like receptor signaling pathway; Herpes simplex infection; Hepatitis C; RIG-I-like receptor signaling pathway0

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