Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (293 IgG)	# Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# Peptides (by Search Engine): C2 Sequest HT (293 WT)	# Peptides (by Search Engine): D2 Sequest HT (293 H KO)	# PSMs (by Search Engine): A2 Sequest HT (293 IgG)	# PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# PSMs (by Search Engine): C2 Sequest HT (293 WT)	# PSMs (by Search Engine): D2 Sequest HT (293 H KO)	Abundance: F1: Sample, 293 IgG	Abundance: F2: Sample, 293 Sel1L KO	Abundance: F3: Sample, 293 WT	Abundance: F4: Sample, 293 H KO	Abundances Count: F1: Sample, 293 IgG	Abundances Count: F2: Sample, 293 Sel1L KO	Abundances Count: F3: Sample, 293 WT	Abundances Count: F4: Sample, 293 H KO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
Low	Q13315	Serine-protein kinase ATM OS=Homo sapiens OX=9606 GN=ATM PE=1 SV=4	0.065	0.974	0	1	1	1	3056	350.5	6.81		1				1				5223887.5				1				cell death;cell organization and biogenesis;metabolic process;regulation of biological process;response to stimulus;transport	cytoplasm;nucleus	catalytic activity;DNA binding;nucleotide binding;protein binding;transporter activity	"Pf00454, Pf02259, Pf02260, Pf11640"	472	ENSG00000149311.18	ATM	11	TP53 Regulates Transcription of Caspase Activators and Caspases; Nonhomologous End-Joining (NHEJ); TP53 Regulates Transcription of DNA Repair Genes; Meiotic recombination; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Resolution of D-loop Structures through Holliday Junction Intermediates; G2/M DNA damage checkpoint; Regulation of HSF1-mediated heat shock response; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Regulation of TP53 Degradation; Presynaptic phase of homologous DNA pairing and strand exchange; Regulation of TP53 Activity through Methylation; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Autodegradation of the E3 ubiquitin ligase COP1; Sensing of DNA Double Strand Breaks; Processing of DNA double-strand break ends; HDR through Single Strand Annealing (SSA); DNA Damage/Telomere Stress Induced Senescence; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	FoxO signaling pathway; Homologous recombination; MicroRNAs in cancer; NF-kappa B signaling pathway; HTLV-I infection; Apoptosis; Transcriptional misregulation in cancer; p53 signaling pathway; Cell cycle; Platinum drug resistance	0

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