Protein FDR Confidence: CombinedAccessionDescriptionExp. q-value: CombinedSum PEP ScoreCoverage [%]# Peptides# PSMs# Unique Peptides# AAsMW [kDa]calc. pI# Peptides (by Search Engine): A2 Sequest HT (293 IgG)# Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO)# Peptides (by Search Engine): C2 Sequest HT (293 WT)# Peptides (by Search Engine): D2 Sequest HT (293 H KO)# PSMs (by Search Engine): A2 Sequest HT (293 IgG)# PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO)# PSMs (by Search Engine): C2 Sequest HT (293 WT)# PSMs (by Search Engine): D2 Sequest HT (293 H KO)Abundance: F1: Sample, 293 IgGAbundance: F2: Sample, 293 Sel1L KOAbundance: F3: Sample, 293 WTAbundance: F4: Sample, 293 H KOAbundances Count: F1: Sample, 293 IgGAbundances Count: F2: Sample, 293 Sel1L KOAbundances Count: F3: Sample, 293 WTAbundances Count: F4: Sample, 293 H KOModificationsBiological ProcessCellular ComponentMolecular FunctionPfam IDsEntrez Gene IDEnsembl Gene IDGene SymbolChromosomeReactome PathwaysKEGG Pathways# Razor Peptides
HighQ14643"Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens OX=9606 GN=ITPR1 PE=1 SV=3"015.11226722758313.76.0461611387913321712.562511cell death;cellular homeostasis;regulation of biological process;response to stimulus;transportcytoplasm;endoplasmic reticulum;membranemetal ion binding;protein binding;receptor activity;signal transducer activity;transporter activity"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"3708ENSG00000150995.18ITPR13Ion homeostasis; FCERI mediated Ca+2 mobilization; PLC beta mediated events; Ca2+ pathway; cGMP effects; DAG and IP3 signaling; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Elevation of cytosolic Ca2+ levels; Effects of PIP2 hydrolysis; Gastrin-CREB signalling pathway via PKC and MAPK; VEGFR2 mediated cell proliferation; CLEC7A (Dectin-1) induces NFAT activation; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Role of phospholipids in phagocytosisDopaminergic synapse; Serotonergic synapse; NOD-like receptor signaling pathway; Vascular smooth muscle contraction; Glutamatergic synapse; cGMP-PKG signaling pathway; Renin secretion; Huntington's disease; Oxytocin signaling pathway; Circadian entrainment; Long-term potentiation; Gap junction; Phosphatidylinositol signaling system; Glucagon signaling pathway; Thyroid hormone synthesis; Pancreatic secretion; Apoptosis; Proteoglycans in cancer; Alzheimer's disease; Long-term depression; Aldosterone synthesis and secretion; Retrograde endocannabinoid signaling; Oocyte meiosis; Gastric acid secretion; Salivary secretion; Inflammatory mediator regulation of TRP channels; GnRH signaling pathway; Estrogen signaling pathway; Cholinergic synapse; Calcium signaling pathway; Platelet activation0

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