High | Q14643 | "Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens OX=9606 GN=ITPR1 PE=1 SV=3" | 0 | 15.112 | 2 | 6 | 7 | 2 | 2758 | 313.7 | 6.04 | | | 6 | 1 | | | 6 | 1 | | 1387913 | 321712.5625 | | | 1 | 1 | | | cell death;cellular homeostasis;regulation of biological process;response to stimulus;transport | cytoplasm;endoplasmic reticulum;membrane | metal ion binding;protein binding;receptor activity;signal transducer activity;transporter activity | "Pf00520, Pf01365, Pf02815, Pf08454, Pf08709" | 3708 | ENSG00000150995.18 | ITPR1 | 3 | Ion homeostasis; FCERI mediated Ca+2 mobilization; PLC beta mediated events; Ca2+ pathway; cGMP effects; DAG and IP3 signaling; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Elevation of cytosolic Ca2+ levels; Effects of PIP2 hydrolysis; Gastrin-CREB signalling pathway via PKC and MAPK; VEGFR2 mediated cell proliferation; CLEC7A (Dectin-1) induces NFAT activation; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Role of phospholipids in phagocytosis | Dopaminergic synapse; Serotonergic synapse; NOD-like receptor signaling pathway; Vascular smooth muscle contraction; Glutamatergic synapse; cGMP-PKG signaling pathway; Renin secretion; Huntington's disease; Oxytocin signaling pathway; Circadian entrainment; Long-term potentiation; Gap junction; Phosphatidylinositol signaling system; Glucagon signaling pathway; Thyroid hormone synthesis; Pancreatic secretion; Apoptosis; Proteoglycans in cancer; Alzheimer's disease; Long-term depression; Aldosterone synthesis and secretion; Retrograde endocannabinoid signaling; Oocyte meiosis; Gastric acid secretion; Salivary secretion; Inflammatory mediator regulation of TRP channels; GnRH signaling pathway; Estrogen signaling pathway; Cholinergic synapse; Calcium signaling pathway; Platelet activation | 0 |