Protein FDR Confidence: Combined	Accession	Description	Exp. q-value: Combined	Sum PEP Score	Coverage [%]	# Peptides	# PSMs	# Unique Peptides	# AAs	MW [kDa]	calc. pI	# Peptides (by Search Engine): A2 Sequest HT (293 IgG)	# Peptides (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# Peptides (by Search Engine): C2 Sequest HT (293 WT)	# Peptides (by Search Engine): D2 Sequest HT (293 H KO)	# PSMs (by Search Engine): A2 Sequest HT (293 IgG)	# PSMs (by Search Engine): B2 Sequest HT (293 Sel1L KO)	# PSMs (by Search Engine): C2 Sequest HT (293 WT)	# PSMs (by Search Engine): D2 Sequest HT (293 H KO)	Abundance: F1: Sample, 293 IgG	Abundance: F2: Sample, 293 Sel1L KO	Abundance: F3: Sample, 293 WT	Abundance: F4: Sample, 293 H KO	Abundances Count: F1: Sample, 293 IgG	Abundances Count: F2: Sample, 293 Sel1L KO	Abundances Count: F3: Sample, 293 WT	Abundances Count: F4: Sample, 293 H KO	Modifications	Biological Process	Cellular Component	Molecular Function	Pfam IDs	Entrez Gene ID	Ensembl Gene ID	Gene Symbol	Chromosome	Reactome Pathways	KEGG Pathways	# Razor Peptides
High	Q8N257	Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=HIST3H2BB PE=1 SV=3	0	43.893	53	8	59	3	126	13.9	10.32	5	7	7	5	8	32	12	7	2014972.625	270209511	11847679.61	4159766.908	1	3	2	3		cell organization and biogenesis	chromosome;cytosol;nucleus	DNA binding;protein binding	"Pf00125, Pf00808"	128312	ENSG00000196890.4	HIST3H2BB	1	SIRT1 negatively regulates rRNA expression; Nonhomologous End-Joining (NHEJ); Activation of anterior HOX genes in hindbrain development during early embryogenesis; NoRC negatively regulates rRNA expression; Meiotic synapsis; Transcriptional regulation by small RNAs; Meiotic recombination; PRC2 methylates histones and DNA; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; HDACs deacetylate histones; Formation of the beta-catenin:TCF transactivating complex; DNA methylation; G2/M DNA damage checkpoint; Packaging Of Telomere Ends; Ub-specific processing proteases; Amyloid fiber formation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; RUNX1 regulates transcription of genes involved in differentiation of HSCs; RNA Polymerase I Chain Elongation; HATs acetylate histones; Deposition of new CENPA-containing nucleosomes at the centromere; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Condensation of Prophase Chromosomes; Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); B-WICH complex positively regulates rRNA expression; RNA Polymerase I Promoter Opening; Oxidative Stress Induced Senescence	Viral carcinogenesis; Systemic lupus erythematosus; Alcoholism	0

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