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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL454919
Molecular formula	C32H36Cl2N2
IUPAC name	(1S,5S)-3-benzyl-8-[bis(2-chlorophenyl)methyl]-3-(pyrrolidin-1-ylmethyl)-8-azabicyclo[3.2.1]octane
Molecular weight	519.554
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	8.4
Synonyms	(rel)-3-benzyl-8-(bis(2-chlorophenyl)methyl)-3-(pyrrolidin-1-ylmethyl)-8-aza-bicyclo[3.2.1]octane BDBM50245825
Inchi Key	AFWWICDZLXWMDM-UIOOFZCWSA-N
Inchi ID	InChI=1S/C32H36Cl2N2/c33-29-14-6-4-12-27(29)31(28-13-5-7-15-30(28)34)36-25-16-17-26(36)22-32(21-25,23-35-18-8-9-19-35)20-24-10-2-1-3-11-24/h1-7,10-15,25-26,31H,8-9,16-23H2/t25-,26-/m0/s1
PubChem CID	44562636
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50245825
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4574	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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