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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL2774146
Molecular formula	C32H24F2N4O6S
IUPAC name	1-[[2,6-difluoro-4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]-6-ethyl-3-[2-(4-methoxyphenyl)-2-oxoethyl]thieno[2,3-d]pyrimidine-2,4-dione
Molecular weight	630.623
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	5.9
Synonyms	AMDWDZCCHMYHJH-UHFFFAOYSA-N CHEMBL3640162 1-{[3,5-difluoro-2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-6-ethyl-3-[2-(4-methoxyphenyl)-2-oxoethyl]thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione US8501750, 197 BDBM99984 SCHEMBL13311615 [ Show all ]
Inchi Key	AMDWDZCCHMYHJH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H24F2N4O6S/c1-3-20-14-23-29(40)37(16-27(39)17-8-10-19(43-2)11-9-17)32(42)38(30(23)45-20)15-24-25(33)12-18(13-26(24)34)21-6-4-5-7-22(21)28-35-31(41)44-36-28/h4-14H,3,15-16H2,1-2H3,(H,35,36,41)
PubChem CID	136052332
ChEMBL	CHEMBL3640162
IUPHAR	N/A
BindingDB	99984
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8787	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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