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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3896466
Molecular formula	C26H27F3N2O3
IUPAC name	4-[1-[[6-[[3-(trifluoromethyl)phenyl]methyl]-6-azaspiro[2.5]octane-7-carbonyl]amino]cyclopropyl]benzoic acid
Molecular weight	472.508
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	2.6
Synonyms	SCHEMBL14486697 4-(1-(6-(3-(trifluoromethyl)benzyl)-6-azaspiro[2.5]octane-5-carboxamido)cyclopropyl)benzoic acid US9181279, E9 AUYTYEPFKREYLH-UHFFFAOYSA-N BDBM191549
Inchi Key	AUYTYEPFKREYLH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27F3N2O3/c27-26(28,29)20-3-1-2-17(14-20)16-31-13-12-24(8-9-24)15-21(31)22(32)30-25(10-11-25)19-6-4-18(5-7-19)23(33)34/h1-7,14,21H,8-13,15-16H2,(H,30,32)(H,33,34)
PubChem CID	71186491
ChEMBL	CHEMBL3896466
IUPHAR	N/A
BindingDB	191549
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536377	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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