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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL518988
Molecular formula	C22H22Cl2N2O2S
IUPAC name	2-[10-(3,4-dichlorophenyl)sulfanyl-1-propan-2-yl-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl]acetic acid
Molecular weight	449.39
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.4
Synonyms	2-(10-(3,4-dichlorophenylthio)-1-isopropyl-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl)acetic acid BDBM50277576
Inchi Key	BDEJQAFLKBWLRG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22Cl2N2O2S/c1-12(2)20-19-17(7-8-25-20)26-9-3-4-13(10-18(27)28)21(26)22(19)29-14-5-6-15(23)16(24)11-14/h5-8,11-13H,3-4,9-10H2,1-2H3,(H,27,28)
PubChem CID	44591537
ChEMBL	CHEMBL518988
IUPHAR	N/A
BindingDB	50277576
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20841	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
20842	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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