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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000879430
Molecular formula	C32H35NO5
IUPAC name	5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-piperidin-1-ylpropyl]-4-phenylchromen-2-one
Molecular weight	513.634
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	6.0
Synonyms	REGID_for_CID_16746296 5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-piperidin-1-yl-propyl]-4-phenyl-chromen-2-one HMS2220I09 4-Phenyl-5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-piperidinopropyl]-2H-1-benzopyran-2-one CHEMBL1405092 SMR000465565 5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-piperidin-1-ylpropyl]-4-phenylchromen-2-one HMS3334C07 BDBM79580 NCGC00166474-01 5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-(1-piperidinyl)propyl]-4-phenyl-1-benzopyran-2-one cid_16746296 5,7-dimethoxy-8-[1-(4-methoxyphenyl)-3-piperidino-propyl]-4-phenyl-coumarin KUC101448N [ Show all ]
Inchi Key	BYWUJRKZXJZLPA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H35NO5/c1-35-24-14-12-23(13-15-24)25(16-19-33-17-8-5-9-18-33)30-27(36-2)21-28(37-3)31-26(20-29(34)38-32(30)31)22-10-6-4-7-11-22/h4,6-7,10-15,20-21,25H,5,8-9,16-19H2,1-3H3
PubChem CID	16746296
ChEMBL	CHEMBL1405092
IUPHAR	N/A
BindingDB	79580
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
36158	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418

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