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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL459542
Molecular formula	C28H40N2
IUPAC name	4-methyl-1-[2-[4-[4-[2-(4-methylpiperidin-1-yl)ethyl]phenyl]phenyl]ethyl]piperidine
Molecular weight	404.642
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	6.7
Synonyms	BDBM50412476
Inchi Key	CYSDCSLGWAVYPG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H40N2/c1-23-11-17-29(18-12-23)21-15-25-3-7-27(8-4-25)28-9-5-26(6-10-28)16-22-30-19-13-24(2)14-20-30/h3-10,23-24H,11-22H2,1-2H3
PubChem CID	44588278
ChEMBL	CHEMBL459542
IUPHAR	N/A
BindingDB	50412476
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
53913	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
53912	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
53914	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445
53915	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445

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