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Ligand

NameCHEMBL256492
Molecular formulaC21H27FN2O3
IUPAC name1-[[4-(2-fluoroethoxy)-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Molecular weight374.456
Hydrogen bond acceptor6
Hydrogen bond donor0
XlogP3.6
SynonymsBDBM50373708
Inchi KeyFKHJOYFNYFVDRF-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H27FN2O3/c1-25-19-6-4-3-5-18(19)24-12-10-23(11-13-24)16-17-7-8-20(27-14-9-22)21(15-17)26-2/h3-8,15H,9-14,16H2,1-2H3
PubChem CID44454735
ChEMBLCHEMBL256492
IUPHARN/A
BindingDB50373708
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
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GLASS IDNameUniProtGeneSpeciesLength
804575-hydroxytryptamine receptor 2AP50129HTR2ASus scrofa (Pig)470
80456D(1A) dopamine receptorP50130DRD1Sus scrofa (Pig)446
80458D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
80459D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
523870D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467

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