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Ligand

NameCHEMBL217575
Molecular formulaC24H24F3N3O
IUPAC name(E)-N-[4-(dimethylamino)-2-propylquinolin-6-yl]-3-[4-(trifluoromethyl)phenyl]prop-2-enamide
Molecular weight427.471
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP5.6
SynonymsBDBM50193611
SCHEMBL6203989
(E)-N-(4-(dimethylamino)-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
SCHEMBL6203995
Inchi KeyGNDQGVNJNAVFDD-MDWZMJQESA-N
Inchi IDInChI=1S/C24H24F3N3O/c1-4-5-18-15-22(30(2)3)20-14-19(11-12-21(20)28-18)29-23(31)13-8-16-6-9-17(10-7-16)24(25,26)27/h6-15H,4-5H2,1-3H3,(H,29,31)/b13-8+
PubChem CID44417992
ChEMBLCHEMBL217575
IUPHARN/A
BindingDB50193611
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
100469Melanin-concentrating hormone receptor 1Q99705MCHR1Homo sapiens (Human)422
100470Melanin-concentrating hormone receptor 2Q969V1MCHR2Homo sapiens (Human)340

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