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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1922015
Molecular formula	C22H24FN5O2
IUPAC name	4-N-(3-fluoro-4-methoxyphenyl)-2-N-(4-methoxyphenyl)-6-pyrrolidin-1-ylpyrimidine-2,4-diamine
Molecular weight	409.465
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.9
Synonyms	SCHEMBL10144179
Inchi Key	IYBJEGSSKQTJDP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24FN5O2/c1-29-17-8-5-15(6-9-17)25-22-26-20(14-21(27-22)28-11-3-4-12-28)24-16-7-10-19(30-2)18(23)13-16/h5-10,13-14H,3-4,11-12H2,1-2H3,(H2,24,25,26,27)
PubChem CID	56643637
ChEMBL	CHEMBL1922015
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
144503	Galanin receptor type 1	P47211	GALR1	Homo sapiens (Human)	349
144504	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387

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