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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Toliprolol
Molecular formula	C13H21NO2
IUPAC name	1-(3-methylphenoxy)-3-(propan-2-ylamino)propan-2-ol
Molecular weight	223.316
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	1.9
Synonyms	2-Propanol, 1-[(1-methylethyl)amino]-3-(3-methylphenoxy)- EINECS 220-905-6 KO-592 [As Hydrochloride] 1-(3'-methyl-phenoxy)-3-(iso-propylamino)-2-propanol 1-(Isopropylamino)-3-(3-methylphenoxy)-2-propanol # AKOS008962502 ICI-45763 [As Hydrochloride] MHIP Toliprololum [INN-Latin] 2-Propanol, 1-((1-methylethyl)amino)-3-(3-methylphenoxy)- (9CI) KO 592 (Salt/Mix) SR-01000945167 1-(3'-methylphenoxy)-3-(iso-propylamino)-2-propanol 2933-94-0 ICI 45763 [AS HYDROCHLORIDE] LS-122425 Toliprolol [INN] 1-(Isopropylamino)-3-(m-tolyloxy)-2-propanol BRN 1874722 Isopropylamino-1-m-tolyloxy-3-propan-2-ol NXQMNKUGGYNLBY-UHFFFAOYSA-N 2-Propanol, 1-(isopropylamino)-3-(m-tolyloxy)- CHEMBL67096 KO 592 [AS HYDROCHLORIDE] SR-01000945167-2 1-(3-methylphenoxy)-3-(propan-2-ylamino)propan-2-ol AC1L2B8T ICI-45763 (Salt/Mix) MCULE-3181316548 Toliprololum 2-Propanol, 1-((1-methylethyl)amino)-3-(3-methylphenoxy)- CHEBI:134918 Isopropylamino-1-m-tolyloxy-3-propan-2-ol [German] SCHEMBL79267 [ Show all ]
Inchi Key	NXQMNKUGGYNLBY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H21NO2/c1-10(2)14-8-12(15)9-16-13-6-4-5-11(3)7-13/h4-7,10,12,14-15H,8-9H2,1-3H3
PubChem CID	18047
ChEMBL	CHEMBL67096
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
234591	Beta-2 adrenergic receptor	Q28044	ADRB2	Bos taurus (Bovine)	418
234592	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
234593	Beta-2 adrenergic receptor	Q8K4Z4	Adrb2	Cavia porcellus (Guinea pig)	418

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