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Ligand

NameDpt-prostaglandin E1
Molecular formulaC22H30O5
IUPAC name7-[(1R,2R)-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]heptanoic acid
Molecular weight374.477
Hydrogen bond acceptor5
Hydrogen bond donor2
XlogP3.5
Synonyms80558-61-8
M&B 28767
UNII-70K4BF31QF
11-Deoxy-16-phenoxy-17,18,19,20-tetranorprostaglandin E1
D0BN1U
[ Show all ]
Inchi KeyNZGFSDWJUZOAAX-KAVAACISSA-N
Inchi IDInChI=1S/C22H30O5/c23-18(16-27-19-8-4-3-5-9-19)14-12-17-13-15-21(24)20(17)10-6-1-2-7-11-22(25)26/h3-5,8-9,12,14,17-18,20,23H,1-2,6-7,10-11,13,15-16H2,(H,25,26)/b14-12+/t17-,18+,20+/m0/s1
PubChem CID5311223
ChEMBLN/A
IUPHAR1913
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 14
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
554439Prostaglandin E2 receptor EP1 subtypeP34995PTGER1Homo sapiens (Human)402
554441Prostaglandin E2 receptor EP1 subtypeP35375Ptger1Mus musculus (Mouse)405
554442Prostaglandin E2 receptor EP1 subtypeP70597Ptger1Rattus norvegicus (Rat)405
554437Prostaglandin E2 receptor EP2 subtypeP43116PTGER2Homo sapiens (Human)358
554446Prostaglandin E2 receptor EP2 subtypeQ62928Ptger2Rattus norvegicus (Rat)357
554438Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
554443Prostaglandin E2 receptor EP3 subtypeP34980Ptger3Rattus norvegicus (Rat)365
554445Prostaglandin E2 receptor EP3 subtypeP43115PTGER3Homo sapiens (Human)390
554435Prostaglandin E2 receptor EP4 subtypeP35408PTGER4Homo sapiens (Human)488
554436Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513
554440Prostaglandin E2 receptor EP4 subtypeP43114Ptger4Rattus norvegicus (Rat)488
554444Prostaglandin F2-alpha receptorP43117PtgfrMus musculus (Mouse)366
554448Prostaglandin F2-alpha receptorP43088PTGFRHomo sapiens (Human)359
554447Thromboxane A2 receptorP21731TBXA2RHomo sapiens (Human)343

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