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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	chloroquine
Molecular formula	C18H26ClN3
IUPAC name	4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine
Molecular weight	319.877
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.6
Synonyms	AC1L1EB8 Delagil Aralen HCl Epitope ID:131785 Avlochlor HMS2090O03 Bemasulph KBio2_000592 BSPBio_002001 Klorokin Chemochin Chloroquina (R)-(-)-Chloroquine Chloroquine [USP:INN:BAN] 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, (R)- Chlorquin 56598-66-4 CQ Quinoline, 7-chloro-4-(4-diethylamino-1-methyl-butylamino)- Resoquine (Salt/Mix) RP-3377 SMP2_000034 Mesylith Spectrum2_000127 N(sup 4)-(7-Chloro-4-quinolinyl)-N(sup 1),N(sup 1)-diethyl-1,4-pentanediamine ST45028748 NCGC00015256-04 W 7618 NCGC00015256-17 NSC 187208 Prestwick3_000548 AK116457 DivK1c_000404 Arechine Gontochin BC208405 Imagon BPBio1_000655 KBio3_001221 Capquin Lopac0_000296 Chlorochin (+)-Chloroquine Chloroquine (VAN) 1,4-Pentanediamine, N(sup 4)-(7-chloro-4-quinolinyl)-N(sup 1),N(sup 1)-diethyl- Chloroquine, 17 34P96M7C4K Clorochina [DCIT] 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline CU-01000012392-2 Resochen Rivoquine SBI-0050284.P004 Malaquin SN-7618 MolMap_000009 Spectrum5_000707 N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine Tanakene NCGC00015256-07 WIN 244 Neochin NSC187208 Quinagamine Dawaquin (TN) Amokin Elestol Arthrochin HCH0027872 Bemaphate KB-258556 BRN 0482809 KH-0005 CHEBI:3638 Chloroin (-)-Chloroquine Chloroquine FNA (TN) 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, (-)- Chloroquinum 54-05-7 Cloroquine AB00053436_06 Quinilon Resoquina Roquine Silbesan Malarex SPBio_000174 N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine ST 21 (pharmaceutical) NCGC00015256-02 UNII-34P96M7C4K NCGC00015256-10 {4-[(7-chloro(4-quinolyl))amino]pentyl}diethylamine Nivaquine Prestwick1_000548 AC1Q2ZA7 Delagil (Salt/Mix) Arechin FT-0623612 Avloclor HSDB 3029 Benaquin KBio2_003160 C07625 KS-00000F97 Chingamin 1, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl- Chloroquine, (R)- 1,4-pentanediamine, N~4~-(7-chloro-4-quinolinyl)-N~1~,N~1~-diethyl-, phosphate (1:2) Cidanchin 58175-86-3 CS-W004760 Quinoline, 7-chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]- Reumachlor Sanoquin SN 6718 Miniquine Spectrum3_000341 n(sup4)-(7-chloro-4-quinolinyl)-n(sup1),4-pentanediamine Tanakan NCGC00015256-05 WE58C2WV1T NCGC00162120-01 NSC-187208 Quinachlor D02366 AKOS015935106 DTXSID2040446 Arequin Gontochin phosphate BDBM22985 Ipsen 225 BRD-A91699651-065-01-1 KBioGR_000778 CCG-204391 LS-141726 Chlorochine (+)-N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine Chloroquine + Proveblue 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl- Chloroquine, D- 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine Cloroquina AB00053436 Resochin Ro 01-6014/N2 SC-48578 Malaquin (Diphosphate) Solprina MolPort-001-783-623 Spectrum_000132 N4-(7-chloro-4-quinolyl)-N1,N1-diethyl-pentane-1,4-diamine Tresochin NCGC00015256-08 WLN: T66 BNJ EMY1&3N2&2 IG NINDS_000404 Pfizerquine Quinercyl DB00608 Aralen EN300-120683 Artrichin Heliopar Bemaphate (Salt/Mix) KBio1_000404 BSPBio_000595 Khingamin CHEMBL76 Chloroquin (.+/-.)-Chloroquine Chloroquine [USAN:INN:BAN] 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, (4R)- Chloroquinum [INN-Latin] Cocartrit AB00053436_07 Quinoline, 7-chloro-4-((4-(diethylamino)-1-methylbutyl)amino)- Resoquine RP 3377 Siragan MCULE-3610827164 SPBio_002516 N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine ST2401962 NCGC00015256-03 UNII-WE58C2WV1T NCGC00015256-13 {4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine Nivaquine B Prestwick2_000548 AC1Q2ZA8 Dichinalex Arechin (Salt/Mix) GNF-Pf-4216 AX8105532 IDI1_000404 Bipiquin KBio2_005728 C18H26ClN3 Lapaquin Chloraquine ( -)-Chloroquine Chloroquine (USP/INN) 1,4-Pentanediamine, N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl- Chloroquine, (S)- 3377 RP opalate Clorochina 7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline CTK1H1520 Quinoscan Reumaquin SBB072644 SN 7618 MLS-0466768.0001 Spectrum4_000279 N(sup4)-(7-chloro-4-quinolinyl)-N(sup1),N(sup1)-diethyl-1,4-pentanediamine Tanakan (Salt/Mix) NCGC00015256-06 WHTVZRBIWZFKQO-UHFFFAOYSA-N NCI60_000894 NSC14050 Quinagamin D09EGZ ALBB-025694 EINECS 200-191-2 Arolen GTPL5535 Bemaco Iroquine BRD-A91699651-316-06-7 KBioSS_000592 CCRIS 3439 Chlorochinum (+-)-Chloroquine Chloroquine Bis-Phosphoric Acid 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, (+)- Chloroquinium 4CH-019706 Cloroquina [INN-Spanish] AB00053436-05 Resochin (TN) Ronaquine SCHEMBL8933 Malaren Sopaquin N'-(7-chloroquinolin-4-yl)-N,N-diethylpentane-1,4-diamine ST 21 N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine Trochin NCGC00015256-09 ZX-AN024208 Nivachine Prestwick0_000548 Quingamine [ Show all ]
Inchi Key	WHTVZRBIWZFKQO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)
PubChem CID	2719
ChEMBL	N/A
IUPHAR	5535
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555154	Mas-related G-protein coupled receptor member X1	Q96LB2	MRGPRX1	Homo sapiens (Human)	322

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