4mpc/1/1:A/2:A

Sequences
>4mpc-a1-m1-cA (length=363) [Search sequence]
SLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLL
PDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMA
QGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDPAHPKHIGSIDPNC
NVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKN
AMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTGYGLP
ISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDW
CVP
>4mpc-a1-m2-cA (length=363) [Search sequence]
SLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLL
PDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMA
QGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDPAHPKHIGSIDPNC
NVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKN
AMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTGYGLP
ISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDW
CVP
Structure information
PDB ID 4mpc (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS2
Assembly ID 1
Resolution 1.699Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 158
Sequence identity between the two chains 1.0
PubMed citation 24356970
Chain information
Chain 1 Chain 2
Model ID 1 2
Chain ID A A
UniProt accession Q15119 Q15119
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:4mpcA BioLiP:4mpcA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 4mpc-a1-m1-cA_4mpc-a1-m2-cA.pdb.gz
Full biological assembly
Download: 4mpc-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 2bu2/1/1:A/2:A 2bu8/1/1:A/2:A 3crl/1/1:A/1:B 4mp2/1/1:A/2:A 4mp7/1/1:A/2:A 4mpe/1/1:A/2:A 4mpn/1/1:A/2:A 4v25/1/1:A/2:A 4v26/1/1:A/2:A 5j6a/1/1:A/2:A 6lil/1/1:B/1:A 6lin/1/1:B/1:A 6lin/2/1:D/1:C 6lio/1/1:A/1:B 7eas/1/1:A/2:A 7ebh/1/1:A/2:A 7vbx/1/1:A/2:A

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