4rlo/3/1:B/1:A

Sequences
>4rlo-a3-m1-cB (length=254) [Search sequence]
KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKKHPFIVDLIYAFQTGGK
LYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLN
HQGHVKLTDFGLCKESITIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENR
KKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWE
ELLARKVEPPFKPL
>4rlo-a3-m1-cA (length=259) [Search sequence]
KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAERNILEEVKHPFIVDL
IYAFQTKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLK
PENIMLNHQGHVKLTDFGLCKEGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPP
FTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF
RHINWEELLARKVEPPFKP
Structure information
PDB ID 4rlo (database links: RCSB PDB PDBe PDBj PDBsum)
Title Human p70s6k1 with ruthenium-based inhibitor EM5
Assembly ID 3
Resolution 2.527Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 128
Sequence identity between the two chains 0.98
PubMed citation 25356520
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession P23443 P23443
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:4rloB BioLiP:4rloA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black]   [White]  
Download: 4rlo-a3-m1-cB_4rlo-a3-m1-cA.pdb.gz
Full biological assembly
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black quality]   [White quality]  
Download: 4rlo-assembly3.cif.gz
Similar dimers
Other dimers with similar sequences and structures 3a60/1/1:B/1:A 4rlp/2/1:A/2:A
Other dimers with similar sequences but different poses
  • 3wf8/2/1:A/2:A 3wf9/2/1:A/2:A
    		•

    [Back to Home]