5v56/1/1:A/1:B

Sequences
>5v56-a1-m1-cA (length=632) [Search sequence]
PPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRC
WAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGC
TNEVQNIKFNSSGQCMVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFG
AVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRAD
GTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTS
YFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYF
LIRGVMTLFSIKSNHAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGL
FEGFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSWEYFCGAVD
AIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIKINETMLRLGIFGFLAFG
FVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKIN
LFAMFGTGIAMSTWVWTKATLLIWRRTWCRLT
>5v56-a1-m1-cB (length=634) [Search sequence]
PPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRC
WAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGC
TNEVQNIKFNSSGQCMVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFG
AVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRAD
GTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTS
YFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYF
LIRGVMTLFSIKSNHAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGL
FEGFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSWEYFCGAVD
AIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIKINETMLRLGIFGFLAFG
FVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPDCEIKNRPSLLVEKINLFAMFG
TGIAMSTWVWTKATLLIWRRTWCRLTGQSDDHHH
Structure information
PDB ID 5v56 (database links: RCSB PDB PDBe PDBj PDBsum)
Title 2.9A XFEL structure of the multi-domain human smoothened receptor (with E194M mutation) in complex with TC114
Assembly ID 1
Resolution 2.9Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 18
Sequence identity between the two chains 0.991
PubMed citation 28513578
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID A B
UniProt accession Q99835 Q99835
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:5v56A BioLiP:5v56B
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 5v56-a1-m1-cA_5v56-a1-m1-cB.pdb.gz
Full biological assembly
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Download: 5v56-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 1wsw/1/1:A/2:A 1xyy/1/1:A/2:A
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