5v56/1/1:A/1:B

Sequences

>5v56-a1-m1-cA (length=632) [Search sequence]

PPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRC WAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGC TNEVQNIKFNSSGQCMVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFG AVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRAD GTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTS YFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYF LIRGVMTLFSIKSNHAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGL FEGFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSWEYFCGAVD AIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIKINETMLRLGIFGFLAFG FVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKIN LFAMFGTGIAMSTWVWTKATLLIWRRTWCRLT

>5v56-a1-m1-cB (length=634) [Search sequence]

PPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRC WAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGC TNEVQNIKFNSSGQCMVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFG AVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRAD GTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTS YFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYF LIRGVMTLFSIKSNHAKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGL FEGFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSWEYFCGAVD AIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIKINETMLRLGIFGFLAFG FVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPDCEIKNRPSLLVEKINLFAMFG TGIAMSTWVWTKATLLIWRRTWCRLTGQSDDHHH

Structure information

PDB ID	5v56 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	2.9A XFEL structure of the multi-domain human smoothened receptor (with E194M mutation) in complex with TC114
Assembly ID	1
Resolution	2.9Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	18
Sequence identity between the two chains	0.991
PubMed citation	28513578

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	Q99835	Q99835
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:5v56A	BioLiP:5v56B

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 5v56-a1-m1-cA_5v56-a1-m1-cB.pdb.gz

Full biological assembly Download: 5v56-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences but different poses

1wsw/1/1:A/2:A 1xyy/1/1:A/2:A