6aak/2/1:D/1:C

Sequences
>6aak-a2-m1-cD (length=266) [Search sequence]
PTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQ
ILKALHSDFIVKYRGVSYSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGME
YLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDVVSPIFWYAPESLSDNIFS
RQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMPALSRLLELLEEGQRLPAPPACPAEVHE
LMKLCWAPSPQDRPSFSALGPQLDML
>6aak-a2-m1-cC (length=274) [Search sequence]
PTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQ
ILKALHSDFIVKYRGVSYSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGME
YLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDVVREPGQSPIFWYAPESLS
DNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGPALSRLLELLEEGQRLPAPPA
CPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLW
Structure information
PDB ID 6aak (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of JAK3 in complex with peficitinib
Assembly ID 2
Resolution 2.67Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 39
Sequence identity between the two chains 1.0
PubMed citation 30145050
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID D C
UniProt accession P52333 P52333
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:6aakD BioLiP:6aakC
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 6aak-a2-m1-cD_6aak-a2-m1-cC.pdb.gz
Full biological assembly
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Download: 6aak-assembly2.cif.gz
Similar dimers

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