7laf/1/1:B/1:A

Sequences
>7laf-a1-m1-cB (length=655) [Search sequence]
HMAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLTAGAEEDFQVTLPEDVGRVLL
LRVHKAAWFCRWFQLTPPGHLLFPCYQWLEGAGTLVLQEGTAKVSWADHHPVLQQQRQEE
LQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLL
DRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNF
PVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSP
GCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLP
EVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSEL
IQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDES
VQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQF
DSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLG
TYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI
>7laf-a1-m1-cA (length=663) [Search sequence]
SHMAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDFTAGAEEDFQVTLPEDVGR
VLLLRVHKAGPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQEGTAKVSWADHHPV
LQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFA
EMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRR
CHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAP
MTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTH
LLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGI
GIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIG
IYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKH
AAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKE
PGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENS
VSI
Structure information
PDB ID 7laf (database links: RCSB PDB PDBe PDBj PDBsum)
Title 15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor
Assembly ID 1
Resolution 2.44Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 58
Sequence identity between the two chains 1.0
PubMed citation 34500187
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession O15296 O15296
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:7lafB BioLiP:7lafA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 7laf-a1-m1-cB_7laf-a1-m1-cA.pdb.gz
Full biological assembly
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Download: 7laf-assembly1.cif.gz

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