8ig0/2/1:C/1:D |
| >8ig0-a2-m1-cC (length=483) [Search sequence] |
GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPEL
TFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKV
SDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDH
AWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVC
AINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTL
YHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIY
KEFFEVANDVIPNLLKEAASLSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFL
VQSLGRFEGQVRQKVRIVSGTVAGTARGPVLTFQSEKMKGMKELLVATKINSSAIKLQLT
AQS |
| >8ig0-a2-m1-cD (length=485) [Search sequence] |
GLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPEL
TFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKV
SDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDH
AWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVC
AINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTL
YHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIY
KEFFEVANDVIPNLLKEAASLLEASALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWA
TFLVQSLGRFEGQVRQKVRIVSGTVAGTARGGPVLTFQSEKMKGMKELLVATKINSSAIK
LQLTA |
|
| PDB ID |
8ig0 (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Crystal structure of menin in complex with DS-1594b |
| Assembly ID |
2 |
| Resolution |
2.6Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
47 |
| Sequence identity between the two chains |
0.996 |
| PubMed citation |
36841758 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
C |
D |
| UniProt accession |
O00255 |
O00255 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:8ig0C |
BioLiP:8ig0D |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
|
Full biological assembly
|
|
| Other dimers with similar sequences and structures |
3u84/3/2:B/1:A 8ig0/1/1:A/1:B |
| Other dimers with similar sequences but different poses |
3u85/2/1:A/2:A 4i80/1/1:A/2:A |
|