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Ligand

NameCHEMBL2205816
Molecular formulaC18H20N2O
IUPAC name5-(2-pyridin-2-ylethyl)-5-azahexacyclo[5.4.1.02,6.03,10.04,8.09,12]dodecan-4-ol
Molecular weight280.371
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP1.8
SynonymsBDBM50401359
Inchi KeyABONQAUMSMWLEK-UHFFFAOYSA-N
Inchi IDInChI=1S/C18H20N2O/c21-18-15-10-7-9-11-12(10)16(18)14(11)17(13(9)15)20(18)6-4-8-3-1-2-5-19-8/h1-3,5,9-17,21H,4,6-7H2
PubChem CID71452384
ChEMBLCHEMBL2205816
IUPHARN/A
BindingDB50401359
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 29
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
10085-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
10325-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
10155-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
10105-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
10275-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
10315-hydroxytryptamine receptor 5AP47898HTR5AHomo sapiens (Human)357
10075-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
10305-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
1005Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
1012Beta-1 adrenergic receptorP08588ADRB1Homo sapiens (Human)477
1013Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413
1021Beta-3 adrenergic receptorP13945ADRB3Homo sapiens (Human)408
1025D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
1016D(1B) dopamine receptorP21918DRD5Homo sapiens (Human)477
1018D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
1022D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
1019D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467
1006Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
1024Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
1028Histamine H2 receptorP25021HRH2Homo sapiens (Human)359

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