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Ligand

NameCicaprost
Molecular formulaC22H30O5
IUPAC name2-[(2E)-2-[(3aS,4S,5R,6aS)-5-hydroxy-4-[(3S,4S)-3-hydroxy-4-methylnona-1,6-diynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]ethoxy]acetic acid
Molecular weight374.477
Hydrogen bond acceptor5
Hydrogen bond donor3
XlogP2.1
Synonyms(2-((2E,3aS,4S,5R,6aS)-Hexahydro-5-hydroxy-4-((3S,4S)-3-hydroxy-4-methyl-1,6-nonadiynyl)-2(1H)-pentalenylidene)ethoxy)acetic acid
95722-07-9
Cicaprostum
SCHEMBL61349
2-[(2E)-2-[(3aS,4S,5R,6aS)-5-hydroxy-4-[(3S,4S)-3-hydroxy-4-methylnona-1,6-diynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]ethoxy]acetic acid
[ Show all ]
Inchi KeyARUGKOZUKWAXDS-SEWALLKFSA-N
Inchi IDInChI=1S/C22H30O5/c1-3-4-5-6-15(2)20(23)8-7-18-19-12-16(9-10-27-14-22(25)26)11-17(19)13-21(18)24/h9,15,17-21,23-24H,3,6,10-14H2,1-2H3,(H,25,26)/b16-9+/t15-,17-,18+,19-,20+,21+/m0/s1
PubChem CID5311044
ChEMBLN/A
IUPHAR1917
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 7
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
553317Prostacyclin receptorP43252PtgirMus musculus (Mouse)415
553318Prostacyclin receptorP43119PTGIRHomo sapiens (Human)386
553315Prostaglandin E2 receptor EP1 subtypeP34995PTGER1Homo sapiens (Human)402
553316Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
553320Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
553321Prostaglandin E2 receptor EP3 subtypeP43115PTGER3Homo sapiens (Human)390
553319Prostaglandin E2 receptor EP4 subtypeP35408PTGER4Homo sapiens (Human)488

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