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Ligand

Nameindomethacin
Molecular formulaC19H16ClNO4
IUPAC name2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
Molecular weight357.79
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP4.3
SynonymsTox21_201791
AB00052022-21
NCGC00015562-25
HMS1568H06
XXE1CET956
[ Show all ]
Inchi KeyCGIGDMFJXJATDK-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
PubChem CID3715
ChEMBLCHEMBL6
IUPHAR1909
BindingDB17638
DrugBankDB00328

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 13
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
41355Cannabinoid receptor 1P21554CNR1Homo sapiens (Human)472
41350Cannabinoid receptor 2P34972CNR2Homo sapiens (Human)360
41356Neuropeptide S receptorQ6W5P4NPSR1Homo sapiens (Human)371
41348Prostaglandin D2 receptorP70263PtgdrMus musculus (Mouse)357
41349Prostaglandin D2 receptor 2Q9Y5Y4PTGDR2Homo sapiens (Human)395
553448Prostaglandin D2 receptor 2Q9Z2J6Ptgdr2Mus musculus (Mouse)382
41351Prostaglandin E2 receptor EP1 subtypeP35375Ptger1Mus musculus (Mouse)405
41347Prostaglandin E2 receptor EP2 subtypeP43116PTGER2Homo sapiens (Human)358
41352Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
41354Prostaglandin E2 receptor EP2 subtypeQ9XT82PTGER2Canis lupus familiaris (Dog)361
41358Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
555634Prostaglandin E2 receptor EP3 subtypeP34980Ptger3Rattus norvegicus (Rat)365
41357Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513

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