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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL360134
Molecular formula	C28H39Cl2N3O2
IUPAC name	(5S)-1-(1-cyclopropylcyclopentyl)-5-(3,4-dichlorophenyl)-5-[2-(3-morpholin-4-ylazetidin-1-yl)ethyl]piperidin-2-one
Molecular weight	520.539
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.5
Synonyms	(S)-1-(1-Cyclopropyl-cyclopentyl)-5-(3,4-dichloro-phenyl)-5-[2-(3-morpholin-4-yl-azetidin-1-yl)-ethyl]-piperidin-2-one BDBM50170969
Inchi Key	GCOOJVFHVKWCPG-HHHXNRCGSA-N
Inchi ID	InChI=1S/C28H39Cl2N3O2/c29-24-6-5-22(17-25(24)30)27(11-12-31-18-23(19-31)32-13-15-35-16-14-32)10-7-26(34)33(20-27)28(21-3-4-21)8-1-2-9-28/h5-6,17,21,23H,1-4,7-16,18-20H2/t27-/m1/s1
PubChem CID	44392318
ChEMBL	CHEMBL360134
IUPHAR	N/A
BindingDB	50170969
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
93121	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
93122	Substance-K receptor	P79218	TACR2	Oryctolagus cuniculus (Rabbit)	384

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