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Ligand

Name15(R)-Prostaglandin E1
Molecular formulaC20H34O5
IUPAC name7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
Molecular weight354.487
Hydrogen bond acceptor5
Hydrogen bond donor3
XlogP3.2
Synonyms7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid
HMS3648D07
V2N896SN9V
15-epi-PGE1
AC1NR1FD
[ Show all ]
Inchi KeyGMVPRGQOIOIIMI-CHCORRSHSA-N
Inchi IDInChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16-,17-,19-/m1/s1
PubChem CID5283056
ChEMBLCHEMBL62570
IUPHARN/A
BindingDB50101828
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 10
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
100247Prostacyclin receptorP43119PTGIRHomo sapiens (Human)386
100246Prostaglandin D2 receptorQ9R261PtgdrRattus norvegicus (Rat)357
100248Prostaglandin E2 receptor EP1 subtypeP35375Ptger1Mus musculus (Mouse)405
100249Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
517848Prostaglandin E2 receptor EP2 subtypeP43116PTGER2Homo sapiens (Human)358
555846Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
100243Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513
517849Prostaglandin E2 receptor EP4 subtypeP35408PTGER4Homo sapiens (Human)488
100244Prostaglandin F2-alpha receptorP37289PTGFRBos taurus (Bovine)362
100245Thromboxane A2 receptorP30987Tbxa2rMus musculus (Mouse)341

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