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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL313424
Molecular formula	C27H29FN6O2
IUPAC name	3-[2-[4-[1-(4-fluorophenyl)-5-(1-methyl-1,2,4-triazol-3-yl)indol-3-yl]piperidin-1-yl]ethyl]-1,3-oxazolidin-2-one
Molecular weight	488.567
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50122824 3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one
Inchi Key	KNLXBMUXNMBWBW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H29FN6O2/c1-31-18-29-26(30-31)20-2-7-25-23(16-20)24(17-34(25)22-5-3-21(28)4-6-22)19-8-10-32(11-9-19)12-13-33-14-15-36-27(33)35/h2-7,16-19H,8-15H2,1H3
PubChem CID	11016418
ChEMBL	CHEMBL313424
IUPHAR	N/A
BindingDB	50122824
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
173486	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
173483	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
173487	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
173480	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
173477	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
173479	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
173485	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
173478	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
173482	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
173484	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
173481	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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